NASA Spaceline Current Awareness List #915 11 September 2020 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Lee SJ, Lehar A, Meir JU, Koch C, Morgan A, Warren LE, Rydzik R, Youngstrom DW, Chandok H, George J, Gogain J, Michaud M, Stoklasek TA, Liu Y, Germain-Lee EL.
Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight.
Proc Natl Acad Sci U S A. 2020 Sep 8. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: ISS results. This article may be obtained online without charge.
Journal Impact Factor: 9.412
Funding: “Research reported in this publication was supported by the International Space Station U.S. National Laboratory under agreement number UA-2019-031, by a Director’s Innovation Fund grant from The Jackson Laboratory (to S.-J.L.), by NIH grants R01AR060636 and R01AG052962 (to S.-J.L.), and by funds from UConn Health (E.L.G.-L. and S.-J.L.) and Connecticut Children’s (E.L.G.-L.).” J.U. Meir, C. Koch, and A. Morgan are affiliated with NASA Johnson Space Center.
2
Ren J, Stankovic AS, Knaus DA, Phillips SD, Kynor DB, Buckey JC.
Urinary calcium for tracking bone loss and kidney stone risk in space.
Aerosp Med Hum Perform. 2020 Sep 1;91(9):689-96.
https://pubmed.ncbi.nlm.nih.
Journal Impact Factor: 0.889
Funding: “This study was funded by NASA Contract NNJ04JA16C and NASA Grant 80NSSC19K1632.”
3
Wu MD, Hodovan J, Kumar K, Moulton B, Olson S, Gilbert A, Wood MD, Lindner JR.
Ponatinib coronary microangiopathy: Novel bedside diagnostic approach and management with N-acetylcysteine.
Blood Adv. 2020 Sep 8;4(17):4083-5.
https://pubmed.ncbi.nlm.nih.
PI: B.D. Levine
Note: This article may be obtained online without charge.
Journal Impact Factor: 4.584
Funding: “J.R.L. is supported by National Institutes of Health, National Heart, Lung, and Blood Institute grants R01-HL078610, R01-HL130046, and P51-OD011092; and National Aeronautics and Space Administration grant 18-18HCFBP_2-0009 [80NSSC20K0987]. M. D. Wu is supported by National Institutes of Health, National Heart, Lung, and Blood Institute grant K08-HL133493.”
4
Larson L, DeChurch L.
Leading teams in the digital age: Four perspectives on technology and what they mean for leading teams.
Leadersh Q. 2020 Feb;31(1):101377. Review.
https://pubmed.ncbi.nlm.nih.
PI: L. DeChurch
Journal Impact Factor: 6.642
Funding: “This paper is based upon work supported by the National Institutes of Health (1R01GM112938-01). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. This paper is also based on work supported by the National Aeronautics and Space Administration (80NSSC18K0276).”
5
Chang DD, Storch EA, Black L, Berk M, Pellis N, Lavretsky H, Sutton J, Ternes K, Shepanek M, Smith E, Abbott R, Eyre HA.
Promoting tech transfer between space and global mental health.
Aerosp Med Hum Perform. 2020 Sep 1;91(9):737-45. Review.
https://pubmed.ncbi.nlm.nih.
Journal Impact Factor: 0.889
Funding: “Michael Berk is supported by a NHMRC Senior Principal Research Fellowship (1059660 and APP1156072).” M. Shepanek is affiliated with NASA Headquarters.
6
Krogman W, Sparks JA, Blancaflor EB.
Cell type-specific imaging of calcium signaling in Arabidopsis thaliana seedling roots using GCaMP3.
Int J Mol Sci. 2020 Sep 2;21(17):E6385.
https://pubmed.ncbi.nlm.nih.
PI: E. Blancaflor
Note: This article may be obtained online without charge.
Journal Impact Factor: 4.556
Funding: “This work was supported by the National Aeronautics and Space Administration (NASA grants 80NSSC18K1462 and 80NSSC19KO129) and the Noble Research Institute LLC.”
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Other papers of interest:
1
Belisheva NK, Tsetlin VV, Martynova АА, Solovievskaya NL, Zavadskaya TS, Pryanichnikov SS, Megorsky VV.
[Water as an indicator of cosmic physical effects on the human organism in the conditions of the Svalbard archipelago].
Aviakosm Ekolog Med. 2020;54(2):96-104. Russian.
https://www.elibrary.ru/item.
Note: From the abstract: “Since water redox potential fluctuations are synchronous with fluctuations in bio-systems functioning we may assume that this detector can be used as a model imitating the liquid medium in organism for studies of the integral effects of spaceflight factors.”
2
de Sousa N, Caporicci M, Vandersteen J, Rojo-Laguna JI, Saló E, Adell T, Auletta G, van Loon JJWA.
Molecular impact of launch related dynamic vibrations and static hypergravity in planarians.
npj Microgravity. 2020 Sep 8;6(1):25.
https://www.nature.com/
Note: The Large Diameter Centrifuge was used. This article may be obtained online without charge.
3
Fan Z, Wu B, Qu J, Du S, Xin B, Xu D, Li Y, Chen Y, Chen Y, Zhang C.
[Research progress of TCM etiology, pathogenesis and protective measures for post spaceflight orthostatic intolerance].
Space Med Med Eng. 2020;2020(4):356-64. Chinese.
http://caod.oriprobe.com/
4
Liu Z, Yuan H, Zhou Y, Chen X.
[Advances in research of hemojuvelin and its role in space medicine].
Space Med Med Eng. 2020;2020(4):370-6. Chinese.
http://caod.oriprobe.com/
5
Tomczak A, Jówko E, Różański P.
Survival training effects on oxidative stress and muscle damage biomarkers of Naval cadets.
Aerosp Med Hum Perform. 2020 Sep 1;91(9):720-4.
https://pubmed.ncbi.nlm.nih.
6
Cao Z, Yang Z, Wei S, Zhang X, Guo Y, Han B.
Comprehensive circRNA expression profile and function network in osteoblast-like cells under simulated microgravity.
Gene. 2021 Jan;764:145106. Epub 2020 Sep 6.
https://pubmed.ncbi.nlm.nih.
Note: A Rotary Cell Culture System was used. This article may be obtained online without charge.
7
Golikova ЕА, Andrianova IV, Buravkova LB.
[Methodical approaches to studying the effects of simulated microgravity on co-cultured hemopoietic progenitors and mesenchymal stromal cells].
Aviakosm Ekolog Med. 2020;54(2):38-44. Russian.
https://www.elibrary.ru/item.
Note: The method used to simulate microgravity is not identified in the available abstract.
8
Turroni S, Magnani M, KC P, Lesnik P, Vidal H, Heer M.
Gut microbiome and space travelers’ health: State of the art and possible pro/prebiotic strategies for long-term space missions.
Front Physiol. 2020 Sep 8;11:1135. Review.
https://www.frontiersin.org/
Note: This article may be obtained online without charge.
9
Arbeille P, Greaves D, Guillon L, Besnard S.
Thigh cuff effects on venous flow redistribution during 4 days in dry immersion.
Aerosp Med Hum Perform. 2020 Sep 1;91(9):697-702.
https://pubmed.ncbi.nlm.nih.
Note: Dry immersion was used.
10
Gao R, Chilibeck PD.
Nutritional interventions during bed rest and spaceflight: Prevention of muscle mass and strength loss, bone resorption, glucose intolerance, and cardiovascular problems.
Nutr Res. 2020 Oct;82:11-24. Review. Epub 2020 Jul 8.
https://pubmed.ncbi.nlm.nih.
11
Weidauer L, Zwart MB, Clapper J, Albert J, Vukovich M, Specker B.
Neuromuscular performance changes throughout the menstrual cycle in physically active females.
J Musculoskelet Neuronal Interact. 2020 Sep 1;20(3):314-24.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
12
Ulanova AD, Gritsyna YV, Bobylev AG, Yakupova EI, Zhalimov VK, Belova SP, Mochalova EP, Nemirovskaya TL, Shenkman BS, Vikhlyantsev IM.
Inhibition of histone deacetylase 1 prevents the decrease in titin (connectin) content and development of atrophy in rat m. soleus after 3-day hindlimb unloading.
Bull Exp Biol Med. 2020 Sep 5. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: Hindlimb unloading study.
13
Donaubauer AJ, Deloch L, Becker I, Fietkau R, Frey B, Gaipl US.
The influence of radiation on bone and bone cells—Differential effects on osteoclasts and osteoblasts.
Int J Mol Sci. 2020 Sep 2;21(17):E6377. Review.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
14
Hart NH, Newton RU, Tan J, Rantalainen T, Chivers P, Siafarikas A, Nimphius S.
Biological basis of bone strength: Anatomy, physiology and measurement.
J Musculoskelet Neuronal Interact. 2020 Sep 1;20(3):347-71. Review.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
15
Moiseev YB.
[Some features of the human spinal column reaction to applied impact].
Aviakosm Ekolog Med. 2020;54(2):72-6. Russian.
https://www.elibrary.ru/item.
16
Fukunaga H.
The effect of low temperatures on environmental radiation damage in living systems: Does hypothermia show promise for space travel?
Int J Mol Sci. 2020 Sep 1;21(17):E6349. Review.
https://pubmed.ncbi.nlm.nih.
Note: From the abstract: “To promote scientific discussions on the application of hibernation in space travel, this literature review provides an overview of the progress to date in the interdisciplinary research field of radiation biology and hypothermia and addresses possible issues related to hypothermic treatments as countermeasures against GCRs.” This article may be obtained online without charge.
17
He S, Zou P, An M, Liu Y, Wang H, Cai Y, Yang H, Wang L.
[Research of motion sickness protection and training effect with virtual swell system].
Space Med Med Eng. 2020;2020(4):327-30. Chinese.
http://caod.oriprobe.com/
18
Pettijohn KA, Pistone DV, Warner AL, Roush GJ, Biggs AT.
Postural instability and seasickness in a motion-based shooting simulation.
Aerosp Med Hum Perform. 2020 Sep 1;91(9):703-9.
https://pubmed.ncbi.nlm.nih.
19
Lebedeva SA, Shved DM, Fedyai SO.
[Investigation of human psychophysiological state in the conditions simulating the microgravity effects using the acoustic method of speech analysis].
Aviakosm Ekolog Med. 2020;54(2):45-51. Russian.
https://www.elibrary.ru/item.
Note: Dry immersion was used.
20
Bubeev YA, Usov VM, Sergeev SF, Kryuchkov BI, Mikhailyuk MV.
[Human interaction with virtual model of a lunar mobile robot in isolation experiments].
Aviakosm Ekolog Med. 2020;54(2):52-9. Russian.
https://www.elibrary.ru/item.
21
Chang EY-W.
Fashion styling and design aesthetics in spacesuit: An evolution review in 60 years from 1960 to 2020.
Acta Astronaut. 2020 Sep 6. [Article in Press]
https://www.sciencedirect.com/
Note: From the abstract: “This paper reviews and discusses those evolutions and revolutions [in spacesuit design] systematically focusing on the styling and design aesthetics in spacesuits for the Demo-2 crew members and the future Starliner flights.”
22
Kudryavtseva NS, Sorokin АЕ.
[Comparative reliability assessment and costing of life support systems for extended interplanetary missions].
Aviakosm Ekolog Med. 2020;54(2):30-7. Russian.
https://www.elibrary.ru/item.
23
Shindo M, Makigawa S, Kodama K, Sugiyama H, Matsumoto K, Iwata T, Wasano N, Kano A, Morita MT, Fujii Y.
Design and chemical synthesis of root gravitropism inhibitors: Bridged analogues of ku-76 have more potent activity.
Phytochemistry. 2020 Nov;179:112508. Epub 2020 Sep 6.
https://pubmed.ncbi.nlm.nih.
