NASA Spaceline Current Awareness List #899 15 May 2020 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Schmidt MA, Meydan C, Schmidt CM, Afshinnekoo E, Mason CE.
The NASA Twins Study: The effect of one year in space on long-chain fatty acid desaturases and elongases.
Lifestyle Genom. 2020 May 6. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
PI: C.E. Mason
Note: ISS results. This article may be obtained online without charge.
Journal Impact Factor: 1.943
Funding: “We would like to thank the Epigenomics Core Facility at Weill Cornell Medicine, the Scientific Computing Unit (SCU), XSEDE Supercomputing Resources, and funding from the Irma T. Hirschl and Monique Weill-Caulier Charitable Trusts, The Bert L & N Kuggie Vallee Foundation, the WorldQuant Foundation, The Pershing Square Sohn Cancer Research Alliance, NASA (NNX14AH50G and NNX17AB26G), the National Institutes of Health (R01AI125416, R01MH117406, R01CA249054, R01AI151059, P01HD067244, and P01CA214274), TRISH (NNX16AO69A: 0107 and NNX16AO69A: 0061), the Bill & Melinda Gates Foundation (OPP1151054), and the Leukemia and Lymphoma Society (LLS) grants (LLS 9238-16, Mak, LLSMCL-982, Chen-Kiang).”
2
Hall MK, Samson PC, Kessler R, Lehnhardt K, Easter BD, Thiel J, Wessells H, Bailey MR, Harper JD.
Pearl-unjammed: The Seattle stone maneuver for ureteropelvic junction urolithiasis.
JACEP Open. 2020 Mar 25. [Article in Press]
https://onlinelibrary.wiley.
PI: M.K. Hall
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “The clinical trial where this work took place is supported by a contract from ZIN Technologies, Inc. and NASA. The technology being tested in this study is the result of funding from NASA and NIH NIDDK (P01 DK043881).”
3
Swanson CM, Shea SA, Kohrt WM, Wright KP, Cain SW, Munch M, Vujovic N, Czeisler CA, Orwoll ES, Buxton OM.
Sleep restriction with circadian disruption negatively alter bone turnover markers in women.
J Clin Endocrinol Metab. 2020 May 4. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
PI: C.A. Czeisler
Journal Impact Factor: 5.605
Funding: “This work was supported by NIH awards K23 AR070275 (Swanson), UL1 TR000128, UL1 TR002535, and a grant from the Center for Women’s Health Research located at the University of Colorado Anschutz Medical Campus. Data Collection Supported by P01 AG009975, K24 HL76446, and NSBRI through NASA NCC 9-58 (HFP01601), and was conducted in the BWH’s General Clinical Research Center supported by the M01 RR02635, and the CCI of the Harvard Clinical and Translational Science Center UL1 RR025758-01. SAS received support from NIH grants R01 HL142064, R01 HL125893, HL125893-03A1 and R01 HL140577, DoD grant PT150133 (to L Hammer) and CDC grant U19 OH010154 (To WK Anger) and The Oregon Institute of Occupational Health Sciences at Oregon Health & Science University via funds from the Division of Consumer and Business Services of the State of Oregon. NV was supported by the following NIH grants: F32AG051325, R01DK099512, R01HL118601, and R01DK105072. OMB was supported in part by NIA (P01 AG009975). ESO as overall PI for the Osteoporotic Fractures in Men (MrOS) Study is supported by NIH funding via the following institutes: the National Institute on Aging, the National Institute of Arthritis and Musculoskeletal and Skin Diseases, the National Center for Advancing Translational Sciences, and NIH Roadmap for Medical Research, under the following grant numbers: U01AG027810, U01AG042124, U01AG042139, U01AG042140, U01 AG042143, U01 AG042145, U01 AG042168, and U01 AR066160. KPW received support from NIH grants R01HL132150, R01HL131458, U01HL111478, R01DK115502, R01DK114272; R01HD087707, R01HL135598, and from a Pac-12 Grant Application and N00014-15-1-2809, Office of Naval Research during the time of this research.”
4
Mousseau TA, Møller AP.
Plants in the light of ionizing radiation: What have we learned from Chernobyl, Fukushima, and other “hot” places?
Front Plant Sci. 2020 May 8;11:552. Review.
https://www.frontiersin.org/
Note: This article may be obtained online without charge.
Journal Impact Factor: 4.106
Funding: “This work was supported in part by the Samuel Freeman Charitable Trust, the CNRS (France) and a grant to TM from the SURA/LASSO Visiting Scientist Program at NASA’s Kennedy Space Center.”
5
Stewart JJ, Adams WW, Escobar CM, López-Pozo M, Demmig-Adams B.
Growth and essential carotenoid micronutrients in Lemna gibba as a function of growth light intensity.
Front Plant Sci. 2020 May 7;11:480.
https://www.frontiersin.org/
PI: B. Demmig-Adams
Note: This article may be obtained online without charge.
Journal Impact Factor: 4.106
Funding: “This work was supported by the Translational Research Institute for Space Health through Cooperative Agreement NNX16AO69A and by the University of Colorado.”
6
Wang H, Wang X, Chen G, Zhang X, Tang X, Park D, Cucinotta FA, Yu DS, Deng X, Dynan WS, Doetsch PW, Wang Y.
Withdrawal: Distinct roles of Ape1 protein, an enzyme involved in DNA repair, in high or low linear energy transfer ionizing radiation-induced cell killing.
J Biol Chem. 2020 May 1;295(18):6249.
https://pubmed.ncbi.nlm.nih.
PI: Y. Wang/NSCOR
Note: The authors retracted the article: Distinct roles of Ape1 protein, an enzyme involved in DNA repair, in high or low linear energy transfer ionizing radiation-induced cell killing. J Biol Chem. 2014;289:30635–30644. The article was cited in SPACELINE Current Awareness List #616, 19 September 2014.
Journal Impact Factor: 4.106
Funding: From the original citation: “This work was supported by grants from the National Aeronautics and Space Administration (NNX11AC30G) and the National Institutes of Health (P30CA138292).”
______________________________
Other papers of interest:
1
van Loon JJWA, Cras P, Bouwens WHACM, Roozendaal W, Vernikos J.
Gravity deprivation: Is it ethical for optimal physiology?
Front Physiol. 2020 May 8;11:470.
https://www.frontiersin.org/
Note: J. Vernikos was affiliated with NASA Headquarters. This article may be obtained online without charge.
2
de la Torre Noetzel R, Ortega Garcia MV, Miller AZ, Bassy O, Granja C, Cubero B, Jordão L, Martinez Frías J, Rabbow E, Backhaus T, Ott S, García Sancho L, de Vera JP.
Lichen vitality after a space flight on board the EXPOSE-R2 facility outside the International Space Station: Results of the Biology and Mars Experiment.
Astrobiology. 2020 May;20(5):583-600.
https://pubmed.ncbi.nlm.nih.
Note: ISS results.
3
O’Sullivan JM.
European Missions to the International Space Station: 2013 to 2019.
Cham, Switzerland: Springer, 2020. 334 p.
https://link.springer.com/
Note: From the abstract: “This book tells the story of the ESA astronauts who have visited the International Space Station and their contributions to its development and success.” Missions described include Volare, Blue Dot, Futura, Iriss, Principia, Proxima, Vita, and Horizons.
4
Fournier R, Harrison RE.
Methods for studying MLO-Y4 osteocytes in collagen-hydroxyapatite scaffolds in the Rotary Cell Culture System.
Connect Tissue Res. 2020 May 6. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: A Rotary Cell Culture System was used.
5
Ponomarev SA, Rykova MP, Antropova EN, Kutko OV, Kalinin SA, Shulgina SM, Sadova AA, Orlova KD, Schmarov VA, Kiseleva DD.
Cytokine profile in volunteers during a 21-day dry immersion without countermeasures.
Hum Physiol. 2020 Mar 1;46(2):175-81.
https://link.springer.com/
Note: Dry immersion was used.
6
Jaki Mekjavic P, Tipton MJ, Mekjavic IB.
The eye in extreme environments.
Exp Physiol. 2020 May 9. [Epub ahead of print] Review.
https://pubmed.ncbi.nlm.nih.
7
Luo D, Edwards S, Smeuninx B, McKendry J, Nishimura Y, Perkins M, Philp A, Joanisse S, Breen L.
Immobilization leads to alterations in intracellular phosphagen and creatine transporter content in human skeletal muscle.
Am J Physiol Cell Physiol. 2020 May 6. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: Immobilization was accomplished via knee brace.
8
Lin CC, Chang YT, Lin RW, Chang CW, Wang GJ, Lai KA.
Single pulsed electromagnetic field restores bone mass and microarchitecture in denervation/disuse osteopenic mice.
Med Eng Phys. 2020 May 4. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: The disuse model was not identified in the available abstract.
9
Liu S, Bi J, Zhang Y, Song Q, Yu M, Sun X, Qu D, Liu S.
Preliminary study on the electromagnetic field treatment of osteoporosis in rats.
Technol Health Care. 2020 Apr 24. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: Right hind limbs were immobilized. This article may be obtained online without charge.
10
Abramowicz A, Labaj W, Mika J, Szoltysek K, Slezak-Prochazka I, Mielanczyk L, Story MD, Pietrowska M, Polanski A, Widlak P.
MicroRNA profile of exosomes and parental cells is differently affected by ionizing radiation.
Radiat Res. 2020 May 8. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
11
Laiakis EC, McCart EA, Deziel A, Rittase WB, Bouten RM, Jha J, Wilkins WL, Day RM, Fornace AJ Jr.
Effect of 3,3′-diindolylmethane on pulmonary injury following thoracic irradiation in CBA mice.
Health Phys. 2020 May 5. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
12
Zhu H, McNamara AL, McMahon SJ, Ramos-Mendez J, Henthorn NT, Faddegon B, Held KD, Perl J, Li J, Paganetti H, Schuemann J.
Cellular response to proton irradiation: A simulation study with TOPAS-nBio.
Radiat Res. 2020 May 13. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
13
Hattori T, Otomi Y, Nakajima Y, Soga K, Wakabayashi K, Iida H, Hoson T.
MCA1 and MCA2 are involved in the response to hypergravity in Arabidopsis hypocotyls.
Plants (Basel). 2020 May 5;9(5):E590.
https://pubmed.ncbi.nlm.nih.
Note: Centrifugation was used. This article may be obtained online without charge.
14
Peiro E, Pannico A, Colleoni SG, Bucchieri L, Rouphael Y, De Pascale S, Paradiso R, Gòdia F.
Air distribution in a fully-closed higher plant growth chamber impacts crop performance of hydroponically-grown lettuce.
Front Plant Sci. 2020 May 13;11:537.
https://www.frontiersin.org/
Note: This article may be obtained online without charge.
15
Vermeulen ACJ, Hubers C, de Vries L, Brazier F.
What horticulture and space exploration can learn from each other: The Mission to Mars initiative in The Netherlands.
Acta Astronaut. 2020 May 11. [Article in Press]
http://www.sciencedirect.com/
Note: From the abstract: “LDE Greenport Hub is an entity of the strategic alliance of the Universities of Leiden, Delft and Erasmus and is focused on horticulture scientific research and education in collaboration with major horticulture industry partners (such as sector association Glastuinbouw Nederland). It has initiated ‘Mission to Mars,’ a program to boost innovation and development of the circular greenhouse by adopting concepts and technologies from space. Space is inherently focused on circularity because of scarce resources.”
16
Liu C, Wanyan X, Xiao X, Zhao J, Duan Y.
Pilots’ mental workload prediction based on timeline analysis.
Technol Health Care. 2020 Apr 24. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: The NASA Task Load Index was used. This article may be obtained online without charge.
