NASA Spaceline Current Awareness List #891 20 March 2020 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
Please note: The latest research on COVID-19 is available from NIH at: https://www.nih.gov/
Papers deriving from NASA support:
1
Xie M, Park D, Sica GL, Deng X.
Bcl2-induced DNA replication stress promotes lung carcinogenesis in response to space radiation.
Carcinogenesis. 2020 Mar 11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: X. Deng
Journal Impact Factor: 4.004
Funding: “This work was supported by NASA grant NNX12AC30G (to X. Deng), by NIH/NCI grants R01CA193828 and R01CA200905 (to X. Deng), by the Winship Research Pathology and Integrated Cellular Imaging shared resource supported by the Winship Cancer Institute of Emory University (P30CAJ 38292), by the Winship Fashion a Cure Research Scholar Award (to X. Deng), a philanthropic award provided by the Winship Cancer Institute of Emory University, and by Winship Endowment Fund (to X. Deng).”
2
DeLong A, Friedman MA, Tucker SM, Krause AR, Kunselman A, Donahue HJ, Lewis GS.
Protective effects of controlled mechanical loading of bone in C57BL6/J mice subject to disuse.
JBMR Plus. 2020 Mar;4(3):e10322.
https://www.ncbi.nlm.nih.gov/
PI: H.J. Donahue
Note: Hindlimb unloading study. This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: PI reports support from NASA.
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Other papers of interest:
1
Rubinfien J, Atabay KD, Nichols NM, Tanner NA, Pezza JA, Gray MM, Wagner BM, Poppin JN, Aken JT, Gleason EJ, Foley KD, Copeland DS, Kraves S, Alvarez Saavedra E.
Nucleic acid detection aboard the International Space Station by colorimetric loop-mediated isothermal amplification (LAMP).
FASEB Bioadv. 2020 Mar;2(3):160-5.
https://www.ncbi.nlm.nih.gov/
Note: ISS results. This article may be obtained online without charge.
2
Bradbury P, Wu H, Choi JU, Rowan AE, Zhang H, Poole K, Lauko J, Chou J.
Modeling the impact of microgravity at the cellular level: Implications for human disease.
Front Cell Dev Biol. 2020 Feb 21;8:96. Review.
https://www.ncbi.nlm.nih.gov/
Note: Simulation methods reviewed include magnetic field levitation, clinostats, Rotating Wall Vessels, and random positioning machines. This article may be obtained online without charge.
3
Huangfu J, Kim HS, Xu K, Ning X, Qin L, Li J, Li C.
Omics analysis reveals the mechanism of enhanced recombinant protein production under simulated microgravity.
Front Bioeng Biotechnol. 2020 Feb 20;8:30.
https://www.ncbi.nlm.nih.gov/
Note: A Rotating Wall Vessel was used. This article may be obtained online without charge.
4
Gao B, Sabnis R, Costantini T, Jinkerson R, Sun Q.
A peek in the micro-sized world: A review of design principles, engineering tools, and applications of engineered microbial community.
Biochem Soc Trans. 2020 Mar 11. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
5
Noh W, Lee M, Kim HJ, Kim KS, Yang S.
Hypergravity induced disruption of cerebellar motor coordination.
Sci Rep. 2020 Mar 10;10(1):4452.
https://www.ncbi.nlm.nih.gov/
Note: Rotation was used. This article may be obtained online without charge.
6
De Martino E, Salomoni SE, Winnard A, McCarty K, Lindsay K, Riazati S, Weber T, Scott J, Green DA, Hides J, Debuse D, Hodges PW, van Dieën JH, Caplan N.
Hypogravity reduces trunk admittance and lumbar muscle activation in response to external perturbations.
J Appl Physiol (1985). 2020 Mar 12. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Parabolic flight results.
7
Herrmann M, Engelke K, Ebert R, Müller-Deubert S, Rudert M, Ziouti F, Jundt F, Felsenberg D, Jakob F.
Interactions between muscle and bone—Where physics meets biology.
Biomolecules. 2020 Mar 10;10(3):E432. Review.
https://www.ncbi.nlm.nih.gov/
Note: Bed rest and spaceflight studies are discussed. This article may be obtained online without charge.
8
Howard EE, Pasiakos SM, Fussell MA, Rodriguez NR.
Skeletal muscle disuse atrophy and the rehabilitative role of protein in recovery from musculoskeletal injury.
Adv Nutr. 2020 Mar 13. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
9
Nguyen TTN, Choi H, Jun HS.
Preventive effects of dulaglutide on disuse muscle atrophy through inhibition of inflammation and apoptosis by induction of Hsp72 expression.
Front Pharmacol. 2020 Feb 21;11:90.
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb immobilization study. This article may be obtained online without charge.
10
Vitadello M, Sorge M, Percivalle E, Germinario E, Danieli-Betto D, Turco E, Tarone G, Brancaccio M, Gorza L.
Loss of melusin is a novel, neuronal NO synthase/FoxO3-independent master switch of unloading-induced muscle atrophy.
J Cachexia Sarcopenia Muscle. 2020 Mar 10. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study. This article may be obtained online without charge.
11
Hosseini Tafreshi SA, Aghaie P, Toghyani MA, Ramazani-Moghaddam-Arani A.
Improvement of ionizing gamma irradiation tolerance of Chlorella vulgaris by pretreatment with polyethylene glycol.
Int J Radiat Biol. 2020 Mar 11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
12
Markina EA, Shtemberg AS, Buravkova LB.
Combined effects of irradiation and hindlimb suspension on erythroid lineage precursors from rat bone marrow.
Bull Exp Biol Med. 2020 Mar 9. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study.
13
Marov MY.
Radiation and space flights safety: An insight.
Acta Astronaut. 2020 Mar 16. [Article in Press]
http://www.sciencedirect.com/
Note: From the abstract: “Different properties of solar electromagnetic and corpuscular radiation with emphasis on its dangerous influence on astronauts and spacecraft equipment and systems are discussed.”
14
Sun JL, Li S, Lu X, Feng JB, Cai TJ, Tian M, Liu QJ.
Identification of the differentially expressed protein biomarkers in rat blood plasma in response to gamma irradiation.
Int J Radiat Biol. 2020 Mar 9. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
15
Leung AK, Hon KL.
Motion sickness: An overview.
Drugs Context. 2019 Dec 13;8:2019-9-4.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
16
Morita H, Kaji H, Ueta Y, Abe C.
Understanding vestibular-related physiological functions could provide clues on adapting to a new gravitational environment.
J Physiol Sci. 2020 Mar 14;70(1):17. Review.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
17
Fadeev KA, Smirnov AS, Zhigalova OP, Bazhina PS, Tumialis AV, Golokhvast KS.
Too real to be virtual: Autonomic and EEG responses to extreme stress scenarios in virtual reality.
Behav Neurol. 2020 Mar 12;2020:5758038.
https://www.hindawi.com/
Note: One of the virtual scenarios is an interactive VR spacewalk on the International Space Station produced by the BBC and available for free at https://store.steampowered.
18
Liu F, Hu W, Vierstra RD.
Corrigendum: The vacuolar protein sorting-38 subunit of the Arabidopsis phosphatidylinositol-3-kinase complex plays critical roles in autophagy, endosome sorting, and gravitropism.
Front Plant Sci. 2020 Mar 18;11:261.
https://www.ncbi.nlm.nih.gov/
Note: Corrigendum: “In the original article, there was a mistake in Panel C of Figure 2. Arabidopsis VPS38 Interacts with Other Subunits of Class-III PtdIns-3 Kinase Complex as published. BiFC fluorescence images for several control plasmids were inadvertently switched with others.” The original article has been updated. The original article was cited in SPACELINE Current Awareness #807, 2018 July 13: Liu F, Hu W, Vierstra RD. The vacuolar protein sorting-38 subunit of the Arabidopsis phosphatidylinositol-3-kinase complex plays critical roles in autophagy, endosome sorting, and gravitropism. Front Plant Sci. 2018 Jun 18;9:781. https://www.ncbi.nlm.nih.gov/
19
Poughon L, Laroche C, Creuly C, Dussap C-G, Paille C, Lasseur C, Monsieurs P, Heylen W, Coninx I, Mastroleo F, Leys N.
Limnospira indica PCC8005 growth in photobioreactor: Model and simulation of the ISS and ground experiments.
Life Sci Space Res. 2020 Mar 13. [Article in Press]
http://www.sciencedirect.com/
20
Bates RE, Kesselring GM, Breunig MJ, Rieck KM.
Overnight cross-coverage on hospital medicine services: Perceived workload based on patient census, pager volumes, and patient acuity.
Hosp Pract (1995). 2020 Mar 15. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: The NASA Task Load Index was used.
21
Hachard B, Noé F, Ceyte H, Trajin B, Paillard T.
Balance control is impaired by mental fatigue due to the fulfilment of a continuous cognitive task or by the watching of a documentary.
Exp Brain Res. 2020 Mar 7. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: The NASA Task Load Index was used.
22
Katz D, Shah R, Kim E, Park C, Shah A, Levine A, Burnett G.
Utilization of a voice-based virtual reality advanced cardiac life support team leader refresher: Prospective observational study.
J Med Internet Res. 2020 Mar 12;22(3):e17425.
https://www.ncbi.nlm.nih.gov/
Note: The NASA Task Load Index was used. This article may be obtained online without charge.
