NASA Spaceline Current Awareness List #884 31 January 2020 (Space Life Science Research Results)
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SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website athttps://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Scott RA, Tarver WJ, Brunstetter TJ, Urquieta E.
Optic nerve tortuosity on Earth and in space.
Aerosp Med Hum Perform. 2020 Feb 1;91(2):91-7. Review.
https://www.ncbi.nlm.nih.gov/
Journal Impact Factor: 0.889
Funding: “Emmanuel Urquieta was supported by the Translational Research Institute for Space Health through NASA NNX-16AO69A.”
2
Axpe E, Chan D, Abegaz MF, Schreurs AS, Alwood JS, Globus RK, Appel EA.
A human mission to Mars: Predicting the bone mineral density loss of astronauts.
PLoS One. 2020 Jan 23;15(1):e0226434.
https://www.ncbi.nlm.nih.gov/
Note: The authors introduce “a predictive mathematical model for the BMD loss defined by an exponential decrease in load bearing bones of the astronauts. By using this model, we predict BMD loss in the femoral neck for two potential missions to Mars.” This article may be obtained online without charge.
Journal Impact Factor: 11.048
Funding: “EAA is thankful for funding from the Center for Human Systems Immunology with Bill and Melinda Gates Foundation OPP1113682. E.A. is thankful for funding support from a Stanford Bio-X Interdisciplinary Initiatives Program Round 8 (2016) Seed Grant, a postdoctoral fellowship of the Basque Government and the Basque Government Grant No. IT-1005-16. D.C. is grateful for an award by the Department of Defense, Air Force Office of Scientific Research, National Defense Science and Engineering Graduate (ND-SEG) Fellowship, 32 CFR168a with government support under FA9550-11-C-0028.” E. Axpe, M.F. Abegaz, A-S. Schreurs, J.S. Alwood, and R.K. Globus are affiliated with NASA Ames Research Center.
3
Cornforth MN.
Occam’s broom* and the dirty DSB: Cytogenetic perspectives on cellular response to changes in track structure and ionization density.
Int J Radiat Biol. 2020 Jan 23. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
PI: M.N. Cornforth
Note: From the Footnote: “*As opposed to Occam’s Razor, ‘Occam’s Broom’ was introduced by the late Sydney Brenner (1927-2019) to describe a situation in which inconvenient facts are ‘swept under the rug’ for the convenience of preserving a popular scientific narrative. (S. Brenner, Curr. Biol (3) p 202 1997).”
Journal Impact Factor: 6.203
Funding: “This work was funded by grant NNX15AG74G from the National Aeronautics and Space Administration (NASA).”
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Other papers of interest:
1
Kuzichkin DS, Markin AA, Juravlyova OA, Krivitsyna ZA, Vostrikova LV, Zabolotskaya IV, Loginov VI.
Effect of total duration and amount of performed space flights on the human plasma hemostasis system.
Hum Physiol. 2019 Nov;45(6):701-4.
https://link.springer.com/
Note: ISS results. Originally published in Russian in Fiziologiya Cheloveka, 2019;45(6):133-6.
2
Lee PJ, Cho N, Yoo HM, Kim HP.
Active turnover of heme in hibernation period in mammals.
Front Physiol. 2020 Jan 15;10:1586.
https://www.frontiersin.org/
Note: This article may be obtained online without charge.
3
Dufrêne YF, Persat A.
Mechanomicrobiology: How bacteria sense and respond to forces.
Nat Rev Microbiol. 2020 Jan 20. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
4
Senatore G, Mastroleo F, Leys N, Mauriello G.
Growth of Lactobacillus reuteri DSM17938 under two simulated microgravity systems: Changes in reuterin production, gastrointestinal passage resistance, and stress genes expression response.
Astrobiology. 2020 Jan;20(1):1-14.
https://www.ncbi.nlm.nih.gov/
Note: A rotating wall vessel and random positioning machine were used.
5
Fagoni N, Bruseghini P, Adami A, Capelli C, Lador F, Moia C, Tam E, Bringard A, Ferretti G.
Effect of lower body negative pressure on phase I cardiovascular responses at exercise onset.
Int J Sports Med. 2020 Jan 20. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
6
Kiznys D, Vencloviene J, Milvidaitė I.
The associations of geomagnetic storms, fast solar wind, and stream interaction regions with cardiovascular characteristic in patients with acute coronary syndrome.
Life Sci Space Res. 2020 Jan 25. [Article in Press]
http://www.sciencedirect.com/
7
Gingery A, Subramaniam M, Pitel KS, Li X, Ke HZ, Turner RT, Iwaniec UT, Hawse JR.
Sclerostin antibody treatment rescues the osteopenic bone phenotype of TGFβ inducible early gene-1 knockout female mice.
J Cell Physiol. 2020 Jan 24. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
8
Lambert CP.
Whole body fat free mass and V̇O2peak in recreationally active men and women.
Aerosp Med Hum Perform. 2020 Feb 1;91(2):102-5.
https://www.ncbi.nlm.nih.gov/
9
MacLennan RJ, Sahebi M, Becker N, Davis E, Garcia JM, Stock MS.
Declines in skeletal muscle quality vs. size following two weeks of knee joint immobilization.
PeerJ. 2020 Jan 13;8:e8224.
https://www.ncbi.nlm.nih.gov/
Note: Immobilization was accomplished via use of crutches and a knee brace. This article may be obtained online without charge.
10
Pillon NJ, Gabriel BM, Dollet L, Smith JAB, Sardón Puig L, Botella J, Bishop DJ, Krook A, Zierath JR.
Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity.
Nat Commun. 2020 Jan 24;11(1):470.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
11
Rezus E, Burlui A, Cardoneanu A, Rezus C, Codreanu C, Pârvu M, Rusu Zota G, Tamba BI.
Inactivity and skeletal muscle metabolism: A vicious cycle in old age.
Int J Mol Sci. 2020 Jan 16;21(2):E592. Review.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
12
Ribeiro Santos V, Dias Correa B, De Souza Pereira CG, Alberto Gobbo L.
Physical activity decreases the risk of sarcopenia and sarcopenic obesity in older adults with the incidence of clinical factors: 24-month prospective study.
Exp Aging Res. 2020 Jan 23. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
13
Czub J, Braziewicz J, Kubala-Kukuś A, Wójcik A.
Analysis of elements secreted by CHO-K1 cells exposed to gamma radiation under different treatments.
Int J Radiat Biol. 2020 Jan 24. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
14
Gramatyka M, Sokół M.
Radiation metabolomics in the quest of cardiotoxicity biomarkers: The review.
Int J Radiat Biol. 2020 Jan 24. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
15
Racine Miousse I, Ewing LE, Skinner CM, Pathak R, Garg S, Kutanzi KR, Melnyk S, Hauer-Jensen M, Koturbash I.
Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome.
Am J Physiol Gastrointest Liver Physiol. 2020 Jan 21. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
16
Sisakht M, Darabian M, Mahmoodzadeh A, Bazi A, Shafiee SM, Mokarram P, Khoshdel Z.
The role of radiation induced oxidative stress as a regulator of radio-adaptive responses.
Int J Radiat Biol. 2020 Jan 24. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
17
Hildreth SB, Foley EE, Muday GK, Helm RF, Winkel BSJ.
The dynamic response of the Arabidopsis root metabolome to auxin and ethylene is not predicted by changes in the transcriptome.
Sci Rep. 2020 Jan 20;10(1):679.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
