NASA Spaceline Current Awareness List #834 1 February 2019 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
1
Vogel J, Thiel CS, Tauber S, Stockmann C, Gassmann M, Ullrich O.
Expression of hypoxia-inducible factor 1α (HIF-1α) and genes of related pathways in altered gravity.
Int J Mol Sci. 2019 Jan 20;20(2):E436.
https://www.ncbi.nlm.nih.gov/
Note: Parabolic flight and TEXUS results. This article may be obtained online without charge.
Journal Impact Factor: 3.687
Funding: “The experiments during the 19th and 23rd DLR parabolic flight campaigns and during the TEXUS-49 and TEXUS-51 suborbital ballistic rocket missions were funded by the Federal Ministry for Economic Affairs and Energy, German Aerospace Center, Federal Republic of Germany, grant no. 50WB1219 and 50WB1519. The experiments during the Swiss Parabolic Flight Campaign were funded by the University of Zurich.” O. Ullrich is affiliated with NASA Kennedy Space Center.
2
Lee JK, Koppelmans V, Riascos RF, Hasan KM, Pasternak O, Mulavara AP, Bloomberg JJ, Seidler RD.
Spaceflight-associated brain white matter microstructural changes and intracranial fluid redistribution.
JAMA Neurol. 2019 Jan 23. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: R.D. Seidler
Note: ISS results. From the Acknowledgements: “This paper was presented at the 2019 NASA Human Research Program Investigators’ Workshop; January 23, 2019; Galveston, Texas.” This article is accompanied by an Editorial: Roberts DR, Petersen LG. Studies of hydrocephalus associated with long-term spaceflight may provide new insights into cerebrospinal fluid flow dynamics here on Earth. JAMA Neurol. 2019 Jan 23. https://www.ncbi.nlm.nih.gov/
Journal Impact Factor: 11.46
Funding: “Supported by National Aeronautics and Space Administration grants NNX11AR02G and NCC 9-58, a grant from the National Space Biomedical Research Institute, and National Institutes of Health grant P41EB015902.”
3
Roberts DR, Petersen LG.
Studies of hydrocephalus associated with long-term spaceflight may provide new insights into cerebrospinal fluid flow dynamics here on Earth.
JAMA Neurol. 2019 Jan 23. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: This editorial comments on the preceding article by Lee JK, Koppelmans V, Riascos RF, Hasan KM, Pasternak O, Mulavara AP, Bloomberg JJ, Seidler RD. Spaceflight-associated brain white matter microstructural changes and intracranial fluid redistribution. JAMA Neurol. 2019 Jan 23. https://www.ncbi.nlm.nih.gov/
Journal Impact Factor: 11.46
Funding: No funding cited. Both authors disclose current NASA funding.
4
Zupanska AK, LeFrois C, Ferl RJ, Paul A-L.
HSFA2 functions in the physiological adaptation of undifferentiated plant cells to spaceflight.
Int J Mol Sci. 2019 Jan 17;20(2):E390.
https://www.ncbi.nlm.nih.gov/
PIs: A-L. Paul, R.J. Ferl
Note: ISS results. This article may be obtained online without charge.
Journal Impact Factor: 3.687
Funding: “This was funded by National Aeronautics and Space Administration, Division of Space Life and Physical Sciences Research and Applications, grants NNX12AK80G and NNX12AN69G to A.-L.P., and R.J.F.”
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Other papers of interest:
1
Li L, Fu Y, Liu H.
Development of effective and safe compound disinfectant for space cabins.
Acta Astronaut. 2019 Jan 30. [Article in Press]
http://www.sciencedirect.com/
2
Sun H, Ling S, Zhao D, Li Y, Zhong G, Guo M, Li Y, Yang L, Du J, Zhou Y, Li J, Liang S, Wang Y, Gao X, Zhang Y, Cao D, Liu C, Jin X, Liu Z, Sun W, Wu X, Song J, Li Y, Shi D.
Panax quinquefolium saponin attenuates cardiac remodeling induced by simulated microgravity.
Phytomedicine. 2018 Aug 11;56:83-93.
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study.
3
Šimunič B, Koren K, Rittweger J, Lazzer S, Reggiani C, Rejc E, Pišot R, Narici M, Degens H.
Tensiomyography detects early hallmarks of bed-rest-induced atrophy before changes in muscle architecture.
J Appl Physiol (1985). 2019 Jan 24. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Bed rest study.
4
Zaidell LN, Pollock RD, James DC, Bowtell JL, Newham DJ, Sumners DP, Mileva KN.
Lower body acceleration and muscular responses to rotational and vertical whole-body vibration at different frequencies and amplitudes.
Dose Response. 2019 Jan-Mar;17(1):
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
5
Benedetti MG, Furlini G, Zati A, Letizia Mauro G.
The effectiveness of physical exercise on bone density in osteoporotic patients.
Biomed Res Int. 2018 Dec 23;2018:4840531. Review.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
6
Bouxsein ML, Eastell R, Lui LY, Wu LA, de Papp AE, Grauer A, Marin F, Cauley JA, Bauer DC, Black DM.
Change in bone density and reduction in fracture risk: A meta-regression of published trials.
J Bone Miner Res. 2019 Jan 23. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
7
Li Y, Gao X, Ling S, Zhong G, Sun W, Liu C, Li J, Song J, Zhao D, Jin X, Li Y, Sun X.
Knockdown of CD44 inhibits the alteration of osteoclast function induced by simulated microgravity.
Acta Astronaut. 2019 Jan 25. [Article in Press]
http://www.sciencedirect.com/
Note: A Rotating Wall Vessel bioreactor was used.
8
Guo X, Zhang M, Gao Y, Cao G, Yang Y, Lu D, Li W.
A genome-wide view of mutations in respiration-deficient mutants of Saccharomyces cerevisiae selected following carbon ion beam irradiation.
Appl Microbiol Biotechnol. 2019 Jan 19. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
9
Kokhan VS, Shakhbazian EV, Markova NA.
Psycho-emotional status but not cognition is changed under the combined effect of ionizing radiations at doses related to deep space missions.
Behav Brain Res. 2019 Jan 15;362:311-8.
https://www.ncbi.nlm.nih.gov/
10
Kowalska A, Nasonova E, Czerski K, Kutsalo P, Pereira W, Krasavin E.
Production and distribution of chromosome aberrations in human lymphocytes by particle beams with different LET.
Radiat Environ Biophys. 2019 Jan 17. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
11
Paganetti H, Blakely E, Carabe-Fernandez A, Carlson DJ, Das IJ, Dong L, Grosshans D, Held KD, Mohan R, Moiseenko V, Niemierko A, Stewart RD, Willers H.
Report of the AAPM TG-256 on the relative biological effectiveness of proton beams in radiation therapy.
Med Phys. 2019 Jan 19. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
12
Tinganelli W, Hitrec T, Romani F, Simoniello P, Squarcio F, Stanzani A, Piscitiello E, Marchesano V, Luppi M, Sioli M, Helm A, Compagnone G, Morganti AG, Amici R, Negrini M, Zoccoli A, Durante M, Cerri M.
Hibernation and radioprotection: Gene expression in the liver and testicle of rats irradiated under synthetic torpor.
Int J Mol Sci. 2019 Jan 16;20(2):E352.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
13
Soleimani M, Ghanati F, Hajebrahimi Z, Hajnorouzi A, Abdolmaleki P, Zarinkamar F.
Energy saving and improvement of metabolism of cultured tobacco cells upon exposure to 2-D clinorotation.
J Plant Physiol. 2019 Mar-Apr;234-235:36-43. Epub 2019 Jan 4.
https://www.ncbi.nlm.nih.gov/
Note: A 2-D clinostat was used.
14
Swarbreck SM, Guerringue Y, Matthus E, Jamieson FJC, Davies JM.
Impairment in karrikin but not strigolactone sensing enhances root skewing in Arabidopsis thaliana.
Plant J. 2019 Jan 19. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
15
Chen S, Epps J.
Atomic head movement analysis for wearable four-dimensional task load recognition.
IEEE J Biomed Health Inform. 2019 Jan 18. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: The NASA Task Load Index was used.
16
Napa S, Moore M, Bardyn T.
Advancing cardiac surgery case planning and case review conferences using virtual reality in medical libraries: Evaluation of the usability of two virtual reality apps.
JMIR Hum Factors. 2019 Jan 16;6(1):e12008.
https://www.ncbi.nlm.nih.gov/
Note: The NASA Task Load Index was used. This article may be obtained online without charge.
