NASA Spaceline Current Awareness List #827 7 December 2018 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Spielmann G, Agha NH, Kunz HE, Simpson RJ, Crucian BE, Mehta SK, Laughlin M, Campbell J.
B-cell homeostasis is maintained during long duration spaceflight.
J Appl Physiol (1985). 2018 Nov 29. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PIs: G. Spielmann, R.J. Simpson, B.E. Crucian
Note: ISS results.
Journal Impact Factor: 3.256
Funding: “This study was funded by a NASA Omnibus Grant NNX17AB16G to GS, a NASA Grant SMO 015 to BC and a NASA Grant NNX12AB48G to RS.”
2
Strollo F, Gentile S, Strollo G, Mambro A, Vernikos J.
Recent progress in space physiology and aging.
Front Physiol. 2018 Nov 29;9:1551. Review.
https://www.ncbi.nlm.nih.gov/
Note: ISS results are discussed. This article may be obtained online without charge.
Journal Impact Factor: 3.394
Funding: No funding cited. J. Vernikos was affiliated with NASA Headquarters.
3
Diaz-Artiles A, Heldt T, Young LR.
Short-term cardiovascular response to short-radius centrifugation with and without ergometer exercise.
Front Physiol. 2018 Nov 13;9:1492.
https://www.ncbi.nlm.nih.gov/
PI: L.R. Young
Note: Short radius centrifugation was used. This article may be obtained online without charge.
Journal Impact Factor: 3.394
Funding: “This project was supported by the MIT/Skolkovo development project (Seed Grant 6925991), and the National Space Biomedical Research Institute through NASA Cooperative Agreement NCC 9-58. In addition, the Fulbright Commission has provided additional support.”
4
Goemaere S, Brenning K, Beyers W, Vermeulen ACJ, Binsted K, Vansteenkiste M.
Do astronauts benefit from autonomy? Investigating perceived autonomy-supportive communication by Mission Support, crew motivation and collaboration during HI-SEAS 1.
Acta Astronaut. 2018 Nov 28. [Article in Press]
http://www.sciencedirect.com/
Journal Impact Factor: 2.227
Funding: No funding cited in the preprint. K. Binsted is PI for the HI-SEAS (Hawai’i Space Exploration Analog and Simulation) project.
5
Schneider J, Saenz-Otero A, Klerman E, Stirling L.
Strategy development pilot study of sleep-restricted operators using small satellites with displays.
Aerosp Med Hum Perform. 2018 Dec 1;89(12):1036-44.
https://www.ncbi.nlm.nih.gov/
PI: E.B. Klerman
Journal Impact Factor: 0.899
Funding: “This work was funded by the MIT School of Engineering (LAS, AS, JJS), NIH K24-HL105664 (EBK), NSBRI HFP04201 (EBK), and a USAF Space Command Fellowship (JJS).”
6
Hall SA, Stirling L.
Human-machine interface degree of freedom effects on performance in space telerobotics.
Aerosp Med Hum Perform. 2018 Dec 1;89(12):1022-30.
https://www.ncbi.nlm.nih.gov/
Journal Impact Factor: 0.899
Funding: “This work was supported by Jet Propulsion Lab Award 1516097. The SSRMS simulator was developed with support from NASA Contract NCC9-58, NSBRI SA1301, NSBRI SA001, and NSBRI NBPF02001.” (PI for the SSRMS simulator: C.M. Oman.)
7
Silverman JD, Durand HK, Bloom RJ, Mukherjee S, David LA.
Correction to: Dynamic linear models guide design and analysis of microbiota studies within artificial human guts.
Microbiome. 2018 Nov 27;6(1):212.
https://www.ncbi.nlm.nih.gov/
PI: L.A. David
Note: From the authors: “Following publication of the original article, the authors noticed an error in the presentation of equations in the PDF version…” The original article was published on 12 Nov 2018 and appeared in SPACELINE Current Awareness List #825, 23 Nov 2018. https://www.ncbi.nlm.nih.gov/
Journal Impact Factor: 9.133
Funding: From the original paper: “JDS and LAD acknowledge support from the Duke University Medical Scientist Training Program (GM007171), the Global Probiotics Council, a Searle Scholars Award, the Hartwell Foundation, an Alfred P. Sloan Research Fellowship, the Translational Research Institute through Cooperative Agreement NNX16AO69A, the Damon Runyon Cancer Research Foundation, the Hartwell Foundation, and NIH 1R01DK116187-01. SM would like to acknowledge the support of grants NSF IIS-1546331, NSF DMS-1418261, NSF IIS-1320357, NSF DMS-1045153, and NSF DMS1613261.”
______________________________
Other papers of interest:
1
Braun N, Binder S, Grosch H, Theek C, Ulker J, Tronnier H, Heinrich U.
Current data on effects of long-term missions on the International Space Station on skin physiological parameters.
Skin Pharmacol Physiol. 2019;32(1):43-51. Epub 2018 Nov 28.
https://www.ncbi.nlm.nih.gov/
Note: ISS results.
2
Braun N, Thomas S, Tronnier H, Heinrich U.
Self-reported skin changes by a selected number of astronauts after long-duration mission on ISS as part of the Skin B project.
Skin Pharmacol Physiol. 2019;32(1):52-7. Epub 2018 Nov 28.
https://www.ncbi.nlm.nih.gov/
Note: ISS results.
3
Yang C, Deng Y, Ren H, Wang R, Li X.
A multi-channel polymerase chain reaction lab-on-a-chip and its application in spaceflight experiment for the study of gene mutation.
Acta Astronaut. 2018 Nov 29. [Article in Press]
http://www.sciencedirect.com/
Note: ISS results.
4
Swaffield TP, Neviaser AS, Lehnhardt K.
Fracture risk in spaceflight and potential treatment options.
Aerosp Med Hum Perform. 2018 Dec 1;89(12):1060-7. Review.
https://www.ncbi.nlm.nih.gov/
Note: ISS results are discussed.
5
Navalta JW, Tanner EA, Bodell NG.
Acute normobaric hypoxia exposure and excess post-exercise oxygen consumption.
Aerosp Med Hum Perform. 2018 Dec 1;89(12):1031-5.
https://www.ncbi.nlm.nih.gov/
6
Ottestad W, Kåsin JI, Hoiseth LØ.
Arterial oxygen saturation, pulse oximetry, and cerebral and tissue oximetry in hypobaric hypoxia.
Aerosp Med Hum Perform. 2018 Dec 1;89(12):1045-9.
https://www.ncbi.nlm.nih.gov/
7
Zhu H, Wang H, Li D, Xiao Z, Su H, Kuang X.
Evaluation of the human thermal comfort under simulated weightlessness: An experimental study based on the power spectrum analysis of the heart rate variability.
Microgravity Sci Technol. 2018 Dec 1. [Article in Press]
https://link.springer.com/
Note: Head-down tilt bed rest study.
8
Feng M, Dang N, Bai Y, Wei H, Meng L, Wang K, Zhao Z, Chen Y, Gao F, Chen Z, Li L, Zhang S.
Differential expression profiles of long noncoding RNAs during the mouse pronuclear stage under normal gravity and simulated microgravity.
Mol Med Rep. 2018 Nov 20. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: A rotary cell culture system was used. This article may be obtained online without charge.
9
Smith JK.
IL-6 and the dysregulation of immune, bone, muscle, and metabolic homeostasis during spaceflight.
npj Microgravity. 2018 Dec 4;4(1):24. Review.
https://www.nature.com/
Note: This article may be obtained online without charge.
10
Khanna K, Mishra KP, Chanda S, Eslavath MR, Ganju L, Kumar B, Singh SB.
Effects of acute exposure to hypobaric hypoxia on mucosal barrier injury and the gastrointestinal immune axis in rats.
High Alt Med Biol. 2018 Nov 28. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
11
Mirzoev TM, Shenkman BS.
Regulation of protein synthesis in inactivated skeletal muscle: Signal inputs, protein kinase cascades, and ribosome biogenesis.
Biochemistry (Mosc). 2018 Nov;83(11):1299-317. Review.
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading studies are reviewed.
12
Wostyn P, De Winne F, Stern C, De Deyn PP.
Dilated prelaminar paravascular spaces as a possible mechanism for optic disc edema in astronauts.
Aerosp Med Hum Perform. 2018 Dec 1;89(12):1089-91.
https://www.ncbi.nlm.nih.gov/
13
Cohen J, Vo NTK, Seymour CB, Mothersill CE.
Parallel comparison of pre-conditioning and post-conditioning effects in human cancers and keratinocytes upon acute gamma irradiation.
Int J Radiat Biol. 2018 Nov 29:1-31. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
14
Deana Y, Burgara-Estrella AJ, Montalvo-Corral M, Angulo-Molina A, Acosta-Elías MA, Silva-Campa E, Sarabia-Sainz JA, Rodríguez-Hernández IC, Pedroza-Montero MR.
Effect of gamma irradiation doses in the structural and functional properties of mice splenic cells.
Int J Radiat Biol. 2018 Nov 29. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
15
Hagiwara Y, Oike T, Niimi A, Yamauchi M, Sato H, Limsirichaikul S, Held KD, Nakano T, Shibata A.
Clustered DNA double-strand break formation and the repair pathway following heavy-ion irradiation.
J Radiat Res. 2018 Nov 22. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
16
Kaur A, Ten Have GAM, Hritzo B, Deutz NEP, Olsen C, Moroni M.
Morphological and functional impairment in the gut in a partial body irradiation minipig model of GI-ARS.
Int J Radiat Biol. 2018 Nov 26. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
17
Li Y, Wang W, Wang T, Wouters MA, Yin Y, Jiao Z, Ma L, Zhang F.
Regulation through microRNAs in response to low-energy N+ ion irradiation in Oryza sativa.
Radiat Res. 2018 Nov 30. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
18
Schuy C, La Tessa C, Horst F, Rovituso M, Durante M, Giraudo M, Bocchini L, Baricco M, Castellero A, Fiore G, Weber U.
Experimental assessment of lithium hydride’s space radiation shielding performance and Monte Carlo benchmarking.
Radiat Res. 2018 Nov 30. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
19
Kokhan VS, Lebedeva-Georgievskaya KB, Kudrin VS, Bazyan AS, Maltsev AV, Shtemberg AS.
An investigation of the single and combined effects of hypogravity and ionizing radiation on brain monoamine metabolism and rats’ behavior.
Life Sci Space Res. 2019 Feb 20;20:12-9. Epub 2018 Nov 29.
http://www.sciencedirect.com/
Note: Hindlimb unloading study.
20
Dakin CJ, Rosenberg A.
Gravity estimation and verticality perception.
Handb Clin Neurol. 2018;159:43-59. Review.
https://www.ncbi.nlm.nih.gov/
21
Idoux E, Tagliabue M, Beraneck M.
No gain no pain: Relations between vestibulo-ocular reflexes and motion sickness in mice.
Front Neurol. 2018 Nov 12;9:918.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
22
Yu M, Zhou R, Wang H, Zhao W.
An evaluation for VR glasses system user experience: The influence factors of interactive operation and motion sickness.
Appl Ergon. 2019 Jan;74:206-13.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
23
Frantzidis CA, Dimitriadou CK, Chriskos P, Gilou SC, Plomariti CS, Gkivogkli PT, Karagianni MA, Konstantara LP, Nday C, Kostakis EK, Bamidis PD, Kourtidou-Papadeli C.
Cortical connectivity analysis for assessing the impact of microgravity and the efficacy of reactive sledge jumps countermeasure to NREM 2 sleep.
Acta Astronaut. 2018 Nov 29. [Article in Press]
http://www.sciencedirect.com/
Note: Head-down tilt bed rest study.
24
Morris NP.
Behavioral health policy for human spaceflight.
Aerosp Med Hum Perform. 2018 Dec 1;89(12):1068-75. Review.
https://www.ncbi.nlm.nih.gov/
