Status Report

NASA Spaceline Current Awareness List #812 24 August 2018 (Space Life Science Research Results)

By SpaceRef Editor
August 24, 2018
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SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

 

Papers deriving from NASA support:

 

1

Miller CA, Kofman IS, Brady RR, May-Phillips TR, Batson CD, Lawrence EL, Taylor LC, Peters BT, Mulavara AP, Feiveson AH, Reschke MF, Bloomberg JJ.

Functional task and balance performance in bed rest subjects and astronauts.

Aerosp Med Hum Perform. 2018 Sep;89(9):805-15.

https://www.ncbi.nlm.nih.gov/pubmed/30126513

PI: J.J. Bloomberg

Note: ISS results; bed rest study.

Journal Impact Factor: 0.933

Funding: “This study was funded by NASA.”

 

2

Reschke MF, Clément G.

Verbal reports of neurovestibular symptoms in astronauts after short-duration space flight.

Acta Astronaut. 2018 Aug 16. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0094576518302236

Note: Space Shuttle results.

Journal Impact Factor: 1.536

Funding: “This work was supported by the National Aeronautics and Space Administration (NASA).”

 

3

Wessel JH, Schaefer CM, Thompson MS, Norcross JR, Bekdash OS.

Retrospective evaluation of clinical symptoms due to mild hypobaric hypoxia exposure in microgravity.

Aerosp Med Hum Perform. 2018 Sep;89(9):792-7.

https://www.ncbi.nlm.nih.gov/pubmed/30126511

Note: Space Shuttle results.

Journal Impact Factor: 0.933

Funding: “This work was made possible through the Human Health and Performance Contract (NNJ15HK11B) between the National Aeronautics and Space Administration and KBRwyle. Funding for this research was provided by the NASA Human Research Program.”

 

4

Imam H, Khan M, Gokhale NS, McIntyre ABR, Kim GW, Jang JY, Kim SJ, Mason CE, Horner SM, Siddiqui A.

N6-methyladenosine modification of hepatitis B virus RNA differentially regulates the viral life cycle.

Proc Natl Acad Sci U S A. 2018 Aug 13. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30104368

PI: C.E. Mason

Journal Impact Factor: 9.661

Funding: “This work was supported in part by National Institutes of Health Grants AI125350, AI139234 (to A.S.), MH117406 (to C.E.M.), AI125416, and AI129851 (to S.M.H. and C.E.M.); the Burroughs Wellcome Fund (S.M.H.); the American Heart Association (N.S.G.); the Irma T. Hirschl and Monique Weill-Caulier Charitable Trusts; the Bert L. and N. Kuggie Vallee Foundation; the WorldQuant Foundation; the Pershing Square Sohn Cancer Research Alliance; NASA (NNX14AH50G and NNX17AB26G); the Bill and Melinda Gates Foundation (OPP1151054 to C.E.M.); and National Research Council of Science and Technology Grant CRC-16-01-KRICT from the Korean government (Ministry of Science, Institute of Chemical Technology and Future Planning) (to S.-J.K.).”

 

5

Giraudo M, Schuy C, Weber U, Rovituso M, Santin G, Norbury JW, Tracino E, Menicucci A, Bocchini L, Lobascio C, Durante M, La Tessa C.

Accelerator-based tests of shielding effectiveness of different materials and multilayers fusing high-energy light and heavy ions.

Radiat Res. 2018 Aug 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30124374

Journal Impact Factor: 2.539

Funding: “This work was supported by the European Space Agency (ESA) under contracts SGI-TASI-PRO-0226 (ROSSINI) and TEC-EES/2014.68/AM (ROSSINI-2).” J.W. Norbury is affiliated with NASA Langley Research Center.

 

6

Krukowski K, Grue K, Frias ES, Pietrykowski J, Jones T, Nelson G, Rosi S.

Female mice are protected from space radiation-induced maladaptive responses.

Brain Behav Immun. 2018 Aug 11. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30107198

PI: S. Rosi

Journal Impact Factor: 5.964

Funding: “This work was supported by NASA grant NNX14AC94G. KK is supported by an NRSA post-doctoral fellowship from the NIA F32AG054126. ESF is supported by the National Institute for General Medicine (NIGMS) Initiative for Maximizing Student Development (R25GM056847) and the National Science Foundation (NSF) Graduate Fellowship Program.”

 

7

Luitel K, Bozeman RG, Kaisani A, Kim SB, Barron S, Richardson JA, Shay JW.

Proton radiation-induced cancer progression.

Life Sci Space Res. 2018 Aug 18. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552418300464

PIs: J.W. Shay; A. Fornace Jr/J.W. Shay/NSCOR

Journal Impact Factor: 1.97

Funding: “This work was supported by NASA Grants # NNX16AE08G and NNX15AI21G to J.W.S. K.L. was supported by Cancer Training Grant T32CA124334. This work was performed in laboratories constructed with support from NIH grant C06 RR30414….We also acknowledge the Harold Simmons NCI Designated Comprehensive Cancer Center Support Grant (CA142543).”

 

8

Wiltshire TJ, Steffensen SV, Fiore SM.

Multiscale movement coordination dynamics in collaborative team problem solving.

Appl Ergon. 2018 Aug 10. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30103905

PI: S. Fiore

Journal Impact Factor: 1.866

Funding: “This research was partially supported by Grant CF16-0455 from the Carlsberg Foundation awarded to Travis J. Wiltshire and by Grant NNX16AO72G from the National Aeronautics and Space Administration awarded to Stephen M. Fiore.”

 

9

Brillada C, Zheng J, Kruger F, Rovira-Diaz E, Askani JC, Schumacher K, Rojas-Pierce M.

Phosphoinositides control the localization of HOPS subunit VPS41, which together with VPS33 mediates vacuole fusion in plants.

Proc Natl Acad Sci U S A. 2018 Aug 13. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30104351

PI: M. Rojas-Pierce

Journal Impact Factor: 9.661

Funding: “This work was supported by National Aeronautics and Space Administration Space Life and Physical Sciences Division [NNX13AM49G (to M.R.-P.)], the National Science Foundation [DBI-1624613 and MCB-1244354 (to M.R.-P.)], and the Deutsche Forschungsgemeinschaft [DFG SFB1101 TPA02 (to K.S.)].”

 

10

Deoli NT, Hasenstein KH.

Irradiation effects of MeV protons on dry and hydrated Brassica rapa seeds.

Life Sci Space Res. 2018 Aug 21. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552418300439

Journal Impact Factor: 1.97

Funding: “This research was supported by NASA grant NNX13AN05A.”

______________________________________________________

 

 

Other papers of interest:

 

1

Li N, Wang C, Sun S, Zhang C, Lu D, Chen Q, Long M.

Microgravity-induced alterations of inflammation-related mechanotransduction in endothelial cells on board SJ-10 satellite.

Front Physiol. 2018 Jul 31;9:1025.

https://www.ncbi.nlm.nih.gov/pubmed/30108515

Note: Chinese SJ-10 recoverable satellite results. This article may be obtained online without charge.

 

2

Arbeille P, Chaput D, Zuj K, Depriester A, Maillet A, Belbis O, Benarroche P, Barde S.

Remote echography between a ground control center and the International Space Station using a tele-operated echograph with motorized probe.

Ultrasound Med Biol. 2018 Aug 7. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30093338

Note: ISS results.

 

3

Grönkvist M, Levin B, Eiken O.

G tolerance during open- vs. closed-loop G-time control.

Aerosp Med Hum Perform. 2018 Sep;89(9):798-804.

https://www.ncbi.nlm.nih.gov/pubmed/30126512 

Note: A centrifuge was used.

 

4

Connolly DM, Lee VM, Hodkinson PD.

White matter status of participants in altitude chamber research and training.

Aerosp Med Hum Perform. 2018 Sep;89(9):777-86.

https://www.ncbi.nlm.nih.gov/pubmed/30126509

 

5

Jang DH, Owiredu S, Ranganathan A, Eckmann DM.

Acute decompression following simulated dive conditions alters mitochondrial respiration and motility.

Am J Physiol Cell Physiol. 2018 Aug 15. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30110561

 

6

Thom SR, Bhopale VM, Yu K, Yang M.

Provocative decompression causes diffuse vascular injury in mice mediated by microparticles containing interleukin-1β.

J Appl Physiol (1985). 2018 Aug 16. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30113270

 

7

Welch D, Buonanno M, Shuryak I, Randers-Pehrson G, Spotnitz HM, Brenner DJ.

Effect of far ultraviolet light emitted from an optical diffuser on methicillin-resistant Staphylococcus aureus in vitro.

PLoS One. 2018 Aug 10;13(8):e0202275.

https://www.ncbi.nlm.nih.gov/pubmed/30096188

Note: This article may be obtained online without charge.

 

8

Vranish JR, Young BE, Stephens BY, Kaur J, Padilla J, Fadel PJ.

Brief periods of inactivity reduce leg microvascular, but not macrovascular, function in healthy young men.

Exp Physiol. 2018 Aug 15. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30110509

 

9

Konishi T, Kurazumi T, Kato T, Takko C, Ogawa Y, Iwasaki K.

Time-dependent changes in cerebral blood flow and arterial pressure during mild +Gz hypergravity.

Aerosp Med Hum Perform. 2018 Sep;89(9):787-91.

https://www.ncbi.nlm.nih.gov/pubmed/30126510

Note: A short-arm human centrifuge was used.

 

10

Masatli Z, Nordine M, Maggioni MA, Mendt S, Hilmer B, Brauns K, Werner A, Schwarz A, Habazettl H, Gunga HC, Opatz OS.

Gender-specific cardiovascular reactions to +Gz interval training on a short arm human centrifuge.

Front Physiol. 2018 Jul 31;9:1028.

https://www.ncbi.nlm.nih.gov/pubmed/30108517

Note: A short-arm human centrifuge was used. This article may be obtained online without charge.

 

11

Layec G, Blain GM, Rossman MJ, Park SY, Hart CR, Trinity JD, Gifford JR, Sidhu SK, Weavil JC, Hureau TJ, Amann M, Richardson RS.

Acute high-intensity exercise impairs skeletal muscle respiratory capacity.

Med Sci Sports Exerc. 2018 Aug 10. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30102675

 

12

Alexander JJ, Sankaran JS, Seldeen KL, Thiyagarajan R, Jacob A, Quigg RJ, Troen BR, Judex S.

Absence of complement factor H alters bone architecture and dynamics.

Immunobiology. 2018 Aug 1. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30107932

 

13

Philbrick KA, Wong CP, Kahler-Quesada AM, Olson DA, Branscum AJ, Turner RT, Iwaniec UT.

Polyethylene particles inserted over calvarium induce cancellous bone loss in femur in female mice.

Bone Rep. 2018 Dec;9:84-92. Epub 2018 Jul 4.

https://www.ncbi.nlm.nih.gov/pubmed/30094298

Note: This article may be obtained online without charge.

 

14

Cucinotta FA, Smirnova OA.

Dependence of the human leukemia risk on the dose and dose rate of continuous irradiation: Modeling study.

Life Sci Space Res. 2018 Aug 18. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552418300300

 

15

Groves AM, Williams JP, Hernady E, Reed C, Fenton B, Love T, Finkelstein JN, Johnston CJ.

A potential biomarker for predicting the risk of radiation-induced fibrosis in the lung.

Radiat Res. 2018 Aug 17. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30117783

 

16

Laiakis EC, Mak TD, Strawn SJ, Wang YW, Moon BH, Ake P, Fornace AJ Jr.

Global metabolomic responses in urine from Atm deficient mice in response to LD50/30 gamma irradiation doses.

Environ Mol Mutagen. 2018 Aug 10. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30095186

 

17

Xu J, Patel NH, Saleh T, Cudjoe EK Jr, Alotaibi M, Wu Y, Lima S, Hawkridge AM, Gewirtz DA.

Differential radiation sensitivity in p53 wild-type and p53-deficient tumor cells associated with senescence but not apoptosis or (nonprotective) autophagy.

Radiat Res. 2018 Aug 22. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30132722

 

18

Bustamante-Sánchez Á, Delgado-Terán M, Clemente-Suárez VJ.

Psychophysiological response of different aircrew in normobaric hypoxia training.

Ergonomics. 2018 Aug 13:1-23. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30101685

 

19

Li R, Peterson N, Walter HJ, Rath R, Curry C, Stoffregen TA.

Real-time visual feedback about postural activity increases postural instability and visually induced motion sickness.

Gait Posture. 2018 Sep;65:251-5.

https://www.ncbi.nlm.nih.gov/pubmed/30107364

 

20

Kamal KY, Herranz R, van Loon J, Medina FJ.

Cell cycle acceleration and changes in essential nuclear functions induced by simulated microgravity in a synchronized Arabidopsis cell culture.

Plant Cell Environ. 2018 Aug 14. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30105864

Note: A Random Positioning Machine was used.

 

21

Lymperopoulos P, Msanne J, Rabara R.

Phytochrome and phytohormones: Working in tandem for plant growth and development.

Front Plant Sci. 2018 Jul 27;9:1037. Review.

https://www.ncbi.nlm.nih.gov/pubmed/30100912

Note: This article may be obtained online without charge.

 

22

Lee JW, Ha KB, Kim YK, Lee JH, Choi IH, Park SH.

Media exchange performance test using the Bradford assay in an automated bioreactor engineering model for space experiments.

SLAS Technol. 2018 Aug 10. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30096255

Note: A bioreactor model was developed.

SpaceRef staff editor.