NASA Spaceline Current Awareness List #810 17 August 2018 (Space Life Science Research Results)
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Please Note: The next issue of SPACELINE Current Awareness (List #811) will be sent on Friday, August 17.
Papers deriving from NASA support:
1
Beheshti A, Ray S, Fogle H, Berrios D, Costes SV.
A microRNA signature and TGF-β1 response were identified as the key master regulators for spaceflight response.
PLoS One. 2018 Jul 25;13(7):e0199621.
https://www.ncbi.nlm.nih.gov/
Note: ISS results. GeneLab: “All raw data used in this manuscript is available on https://genelab.nasa.gov/.” This article may be obtained online without charge.
Journal Impact Factor: 2.806
Funding: “Research funding was provided by the GeneLab Project at NASA Ames Research Center, through NASA’s Space Biology Program in the Division of Space Life and Physical Sciences Research and Applications (SLPSRA).”
2
Ramachandran V, Dalal S, Scheuring RA, Jones JA.
Musculoskeletal injuries in astronauts: Review of pre-flight, in-flight, post-flight, and extravehicular activity injuries.
Curr Pathobiol Rep. 2018 July 28. [Article in Press] Review.
https://link.springer.com/
Note: The studies reviewed data from 1959-2018 and include U.S. space missions during that period. This article is part of the journal’s Topical Collection on the “Effects of the Space Environments on Human Pathobiology.”
Journal Impact Factor: Not available for this journal
Funding: No funding cited. R.A. Scheuring is affiliated with NASA Johnson Space Center.
3
Bell D, Durrance S, Kirk D, Gutierrez H, Woodard D, Avendano J, Sargent JL, Leite C, Saldana B, Melles T, Jackson S, Xu S.
Self-assembly of protein fibrils in microgravity.
Gravit Space Res. 2018 Jul;6(1):10-26.
http://
Note: ISS results. This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “This work was supported by Space Florida, NanoRacks, FSGC, and the Florida Institute of Technology.” D. Woodard is affiliated with NASA Kennedy SpaceCenter.
4
Alula KM, Resau JH, Patel OV.
Chronic exposure to altered gravity during the pregnancy-to-lactation transition affects abundance of cytoskeletal proteins in the rat mammary gland.
Gravit Space Res. 2018 Jul;6(1):58-72.
http://
Note: Centrifugation was used. This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “A particular debt of gratitude is owed to Dr. Karen Plaut (Purdue University) and her collaborators for sharing tissue collected through their NASA grant NNA05CP91A.”
5
Evans JM, Knapp CF, Goswami N.
Artificial gravity as a countermeasure to the cardiovascular deconditioning of spaceflight: Gender perspectives.
Front Physiol. 2018 Jul 6;9:716.
https://www.ncbi.nlm.nih.gov/
Note: Centrifugation was used. This article may be obtained online without charge.
Journal Impact Factor: 4.031
Funding: “The research upon which this review is based, was supported by KY NASA EPSCoR Grant NNX07AT58A and the National Center for Research Resources, and the National Center for Advancing Translational Sciences through NIH Grant UL1TR000117. Facilities support was provided by the Gravitational Branch of NASA Ames Research Center and the Human Research Program of NASA Johnson Space Center.”
6
Moonga SS, Qin YX.
MC3T3 infiltration and proliferation in bovine trabecular scaffold regulated by dynamic flow bioreactor and augmented by low-intensity pulsed ultrasound.
J Orthop Translat. 2018 Jul;14:16-22.
https://www.ncbi.nlm.nih.gov/
PI: Y.X. Qin
Note: This article may be obtained online without charge.
Journal Impact Factor: 2.078
Funding: “This work is supported by the National Institute of Health (AR52379, AR61821) and the National Space Biomedical Research Institute through NASA Cooperative Agreement NCC 9-58.”
7
Li Z, Jella KK, Jaafar L, Li S, Park S, Story MD, Wang H, Wang Y, Dynan WS.
Exposure to galactic cosmic radiation compromises DNA repair and increases the potential for oncogenic chromosomal rearrangement in bronchial epithelial cells.
Sci Rep. 2018 Jul 23;8(1):11038.
https://www.ncbi.nlm.nih.gov/
PIs: W.S. Dynan; Y. Wang/W.S. Dynan/NSCOR; J.D. Minna/M.D. Story/NSCOR
Note: This article may be obtained online without charge.
Journal Impact Factor: 4.259
Funding: “The work was supported by US National Aeronautics and Space Administration (NASA) award NNX15AD63G (to WSD), NASA NSCOR award NNX11AC30G (to Ya Wang) and NASA NSCOR award NNX11AC54G (to John Minna).”
8
Allison KC, Goel N.
Timing of eating in adults across the weight spectrum: Metabolic factors and potential circadian mechanisms.
Physiol Behav. 2018 Aug 1;192:158-66.
https://www.ncbi.nlm.nih.gov/
PI: N. Goel
Note: This article may be obtained online without charge.
Journal Impact Factor: 2.341
Funding: “Both authors derived support for the writing of this review from National Institutes of Health grants NIH R01DK117488 and NIH R21DK100787.” The PI reports funding under NASA NNX14AN49G.
9
Hilleary R, Choi WG, Kim SH, Lim SD, Gilroy S.
Sense and sensibility: The use of fluorescent protein-based genetically encoded biosensors in plants.
Curr Opin Plant Biol. 2018 Dec;46:32-8. Review. Epub 2018 Jul 21.
https://www.ncbi.nlm.nih.gov/
PI: S. Gilroy
Journal Impact Factor: 7.357
Funding: “The work in the authors’ laboratories is supported by grants from the National Science Foundation (MCB1329723 and IOS1557899), The National Aeronautics and Space Administration (NNX17AD52G and NNX14AT25G) and the Graduate School of the University of Wisconsin-Madison. RH was supported by NSF GRF and the Graduate School of the University of Wisconsin-Madison.”
10
Anderson MS, Ewert MK, Keener JF.
Life support baseline values and assumptions document.
Houston, TX: NASA Johnson Space Center, 2018 Jan. 233 p. NASA/TP-2015-218570/Rev 1.
https://ntrs.nasa.gov/?N=123&
Note: This article may be obtained online without charge.
Journal Impact Factor: Not applicable to this publication
Funding: No funding cited. The authors are affiliated with NASA Johnson Space Center.
______________________________
Other papers of interest:
1
Gravely AK, Vlasov A, Freeman A, Wu K, Szewczyk NJ, D’Cruz R, Batt J.
Levels of acid sphingomyelinase (ASM) in Caenorhabditis elegans in microgravity.
Gravit Space Res. 2018 Jul;6(1):27-36.
http://
Note: ISS results. This article may be obtained online without charge.
2
Brcic J, Suedfeld P, Johnson P, Huynh T, Gushin V.
Humor as a coping strategy in spaceflight.
Acta Astronaut. 2018 Jul 26. [Article in Press]
http://www.sciencedirect.com/
Note: Astronauts and cosmonauts who participated in the study have flown on a variety of missions.
3
Wang L, Han F, Zheng HQ.
Photoperiod-controlling guttation and growth of rice seedlings under microgravity on board Chinese Spacelab TG-2.
Microgravity Sci Technol. 2018 Jul 23. [Article in Press]
https://link.springer.com/
Note: Chinese Spacelab TG-2 results.
4
Llanos PJ, Andrijauskaite K, Rubinstein MP, Chan SSL.
Investigation of zebrafish larvae behavior as precursor for suborbital flights: Feasibility study.
Gravit Space Res. 2018 Jul;6(1):37-57.
http://
Note: Centrifugation was used. This article may be obtained online without charge.
5
Maltsev AV.
Agmatine modulates calcium handling in cardiomyocytes of hibernating ground squirrels through calcium-sensing receptor signaling.
Cell Signal. 2018 Nov;51:1-12. Epub 2018 Jul 17.
https://www.ncbi.nlm.nih.gov/
6
Vale P.
Impact of light quality and space weather in Alexandrium catenella (Dinophyceae) cultures.
Life Sci Space Res. 2018 Jul 31. [Article in Press]
http://www.sciencedirect.com/
7
Chang H, Lei T, Ma X, Zhang J, Wang H, Zhang X, Gao YF.
Muscle-specific activation of calpain system in hindlimb unloading rats and hibernating Daurian ground squirrels: A comparison between artificial and natural disuse.
J Comp Physiol B. 2018 Jul 23. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study.
8
Furukawa T, Tanimoto K, Fukazawa T, Imura T, Kawahara Y, Yuge L.
Erratum: Publisher Correction: Simulated microgravity attenuates myogenic differentiation via epigenetic regulations.
npj Microgravity. 2018 Jul 18;4:15.
https://www.ncbi.nlm.nih.gov/
Note: “The original version of this Article contained an error in Fig. 4. Fig. 4B was partly cropped, which obscured some of the sequence information.” This has been corrected in both the PDF and HTML versions of the article. The original citation appeared in SPACELINE Current Awareness List #800, 25 May 2018,https://www.ncbi.nlm.nih.gov/
9
Valenzuela PL, Morales JS, Pareja-Galeano H, Izquierdo M, Emanuele E, de la Villa P, Lucia A.
Physical strategies to prevent disuse-induced functional decline in the elderly.
Ageing Res Rev. 2018 Jul 18;47:80-8.
https://www.ncbi.nlm.nih.gov/
10
Menezes KM, Wang H, Hada M, Saganti PB.
Radiation matters of the heart: A mini review.
Front Cardiovasc Med. 2018 Jul 9;5:83.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
11
Hinterecker T, Leroy C, Kirschhock ME, Zhao M, Butz MV, Bulthoff HH, Meilinger T.
Spatial memory for vertical locations.
J Exp Psychol Learn Mem Cogn. 2018 Jul 26. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
12
Zitting KM, Munch MY, Cain SW, Wang W, Wong A, Ronda JM, Aeschbach D, Czeisler CA, Duffy JF.
Young adults are more vulnerable to chronic sleep deficiency and recurrent circadian disruption than older adults.
Sci Rep. 2018 Jul 23;8(1):11052.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
13
Kozeko LY, Buy DD, Pirko YV, Blume YB, Kordyum EL.
Clinorotation affects induction of the heat shock response in Arabidopsis thaliana seedlings.
Gravit Space Res. 2018 Jul;6(1):2-9.
http://
Note: A clinostat was used. This article may be obtained online without charge.