NASA Spaceline Current Awareness List #788 2 March 2018 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at
https://taskbook.nasaprs.com/
Senior Editor, SPACELINE@nasaprs.com.
Papers deriving from NASA support:
1
Lindner JR, Link J.
Molecular imaging in drug discovery and development.
Circ Cardiovasc Imaging. 2018 Feb;11(2):e005355. Review.
https://www.ncbi.nlm.nih.gov/
PI: J.R. Lindner
Note: This article may be obtained online without charge.
Journal Impact Factor: 6.803
Funding: “Dr Lindner is supported by grants
R01-HL078610 and R01-HL130046 from the National Institutes of Health,
Bethesda, MD. Dr Lindner is also supported by grant 14-14NSBRI1-0025
from the National Space Biomedical Research Institute.
Dr Link is supported by the National Cancer Institute grant
P01CA042045.”
2
Ham DW, Song B, Gao J, Yu J, Sachs RK.
Synergy theory in radiobiology.
Radiat Res. 2017 Dec 29. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Journal Impact Factor: 2.539
Funding: “This work was supported by NASA
(grant no. NNJ16HP221 to RKS) and the UC Berkeley undergraduate research
apprenticeship program (URAP; to DWH, BS, JG and JY).”
3
Hasan KM, Mwangi B, Keser Z, Riascos R, Sargsyan AE, Kramer LA.
Brain quantitative MRI metrics in astronauts as a unique professional group.
J Neuroimaging. 2018 Feb 20. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: R. Riascos
Journal Impact Factor: 1.664
Funding: “The authors would like to thank
NASA Lyndon B. Johnson Space Center Lifetime Surveillance of Astronaut
Health (LSAH) group and Wyle Science, Technology and Engineering experts
for support and efficient reviews. This work
was also funded in part by the DUNN research Foundation.” PI reports
funding through NASA grant NNX15AE25G.
4
Intracranial Pressure and Its Effect on Vision in Space and on Earth: Vision Impairment in Space.
Macias BR, Liu JHK, Otto C, Hargens AR, editors.
Hackensack, NJ: World Scientific, 2017. 291 p.
http://www.worldscientific.
Note: From the introductory chapter: “The
following chapters are a summary of early attempts by the space medicine
community to understand adaptations to microgravity and solve
spaceflight-induced vision impairment.” The individual
chapters are listed below. They review the various aspects of vision
impairment related to intracranial pressure during spaceflight. While
most of the chapters were not funded directly by NASA, the knowledge and
experience gathered in the chapters was made
possible through research performed under grants from the NASA Human
Research Program.
5
Macias BR, Hargens AR.
Introduction to visual impairment and intracranial pressure.
In: Macias BR, Liu JHK, Otto C, Hargens AR, eds.
Intracranial Pressure and Its Effect on Vision in Space and on Earth:
Vision Impairment in Space. Hackensack, NJ: World Scientific, 2017. p.
1-3.
http://www.worldscientific.
Journal Impact Factor: Not applicable to this publication
Funding: No funding cited. B.R. Macias is affiliated with NASA Johnson Space Center.
6
Mader TH, GIbson CR.
Early evidence of vision impairment after long-duration.
In: Macias BR, Liu JHK, Otto C, Hargens AR, eds.
Intracranial Pressure and Its Effect on Vision in Space and on Earth:
Vision Impairment in Space. Hackensack, NJ: World Scientific, 2017. p.
5-22.
http://www.worldscientific.
Journal Impact Factor: Not applicable to this publication
Funding: No funding cited. T.H. Mader is affiliated with NASA Johnson Space Center.
7
Kramer LA.
Eye, orbit, and pituitary MRI: Relevance to space medicine.
In: Macias BR, Liu JHK, Otto C, Hargens AR, eds.
Intracranial Pressure and Its Effect on Vision in Space and on Earth:
Vision Impairment in Space. Hackensack, NJ: World Scientific, 2017. p.
23-38.
http://www.worldscientific.
8
Stenger MB, Laurie SS, Lee SMC.
Fluid shifts and cardiovascular-related factors that may contribute to the VIIP syndrome in astronauts.
In: Macias BR, Liu JHK, Otto C, Hargens AR, eds.
Intracranial Pressure and Its Effect on Vision in Space and on Earth:
Vision Impairment in Space. Hackensack, NJ: World Scientific, 2017. p.
39-68.
http://www.worldscientific.
Journal Impact Factor: Not applicable to this publication
Funding: No funding cited. M.B. Stenger, S.S. Laurie, and S.M.C. Lee are affiliated with NASA Johnson Space Center.
9
Qzarlander S, Williams MA.
Intracranial pressure physiology and VIIP.
In: Macias BR, Liu JHK, Otto C, Hargens AR, eds.
Intracranial Pressure and Its Effect on Vision in Space and on Earth:
Vision Impairment in Space. Hackensack, NJ: World Scientific, 2017. p.
69-90.
http://www.worldscientific.
10
Wilson MH.
High-altitude illness and intracranial pressure.
In: Macias BR, Liu JHK, Otto C, Hargens AR, eds.
Intracranial Pressure and Its Effect on VIsion in Space and on Earth:
Vision Impairment in Space. Hackensack, NJ: World Scientific, 2017. p.
91-105.
http://www.worldscientific.
11
Bershad EM, Dunham R.
Noninvasive measurement of intracranial pressure with the Vittamed absolute value meter.
In: Macias BR, Liu JHK, Otto C, Hargens AR, eds.
Intracranial Pressure and Its Effect on Vision in Space and on Earth:
Vision Impairment in Space. Hackensack, NJ: World Scientific, 2017. p.
107-21.
http://www.worldscientific.
PI: E.M. Bershad
Journal Impact Factor: Not applicable to this publication
Funding: “We thank the National Space Biomedical Research Institute for funding our study.”
12
Otto C.
NASA’s research approach to the visual impairment intracranial pressure risk.
In: Macias BR, Liu JHK, Otto C, Hargens AR, eds.
Intracranial Pressure and Its Effect on Vision in Space and on Earth:
Vision Impairment in Space. Hackensack, NJ: World Scientific, 2017. p.
123-71.
http://www.worldscientific.
Journal Impact Factor: Not applicable to this publication
Funding: No funding cited. C. Otto is affiliated with NASA Johnson Space Center.
13
Roberts DR, McLaren R, Antonucci MU.
Advanced imaging of the intracranial physiology of spaceflight.
In: Macias BR, Liu JHK, Otto C, Hargens AR, eds.
Intracranial Pressure and Its Effect on Vision in Space and on Earth:
Vision Impairment in Space. Hackensack, NJ: World Scientific, 2017. p.
173-224.
http://www.worldscientific.
PI: D.R. Roberts
Journal Impact Factor: Not applicable to this publication
Funding: PI reports funding through NASA grant NNX13AJ92G.
14
Seidler RD, Koppelmans V, Bloomberg J, Mulavara AP.
Sensory and sensorimotor changes with spaceflight: Implications for functional performance.
In: Macias BR, Liu JHK, Otto C, Hargens AR, eds.
Intracranial Pressure and Its Effect on Vision in Space and on Earth:
Vision Impairment in Space. Hackensack, NJ: World Scientific, 2017. p.
225-51.
http://www.worldscientific.
Journal Impact Factor: Not applicable to this publication
Funding: No funding cited. R.D. Seidler, J. Bloomberg, and A.P. Mulavara are affiliated with NASA Johnson Space Center.
15
Scott JM, Charles JB.
Lower body negative pressure as a VIIP countermeasure.
In: Macias BR, Liu JHK, Otto C, Hargens AR, eds.
Intracranial Pressure and Its Effect on Vision in Space and on Earth:
Vision Impairment in Space. Hackensack, NJ: World Scientific, 2017. p.
253-71.
http://www.worldscientific.
Journal Impact Factor: Not applicable to this publication
Funding: No funding cited. J.B. Charles is affiliated with NASA Johnson Space Center.
16
Liu JHK.
A pressure theory links the VIIP Syndrome and eye diseases.
In: Macias BR, Liu JHK, Otto C, Hargens AR, eds.
Intracranial Pressure and Its Effect on Vision in Space and on Earth:
Vision Impairment in Space. Hackensack, NJ: World Scientific, 2017. p.
273-87.
http://www.worldscientific.
______________________________
Other papers of interest:
1
Fox MT, Sidani S, Brooks D, McCague H.
Perceived acceptability and preferences for
low-intensity early activity interventions of older hospitalized medical
patients exposed to bed rest: A cross sectional study.
BMC Geriatr. 2018 Feb 20;18(1):53.
https://www.ncbi.nlm.nih.gov/
Note: Bed rest study. This article may be obtained online without charge.
2
Nilsson A, Bergens O, Kadi F.
Physical activity alters inflammation in older adults by different intensity levels.
Med Sci Sports Exerc. 2018 Feb 16. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
3
van Helmond N, Johnson BD, Holbein WW, Petersen-Jones HG, Harvey RE, Ranadive SM, Barnes JN, Curry TB, Convertino VA, Joyner MJ.
Effect of acute hypoxemia on cerebral blood flow velocity control during lower body negative pressure.
Physiol Rep. 2018 Feb;6(4):e13594.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
4
Brooks MJ, Hajira A, Mohamed JS, Alway SE.
Voluntary wheel running increases satellite cell abundance and improves recovery from disuse in gastrocnemius muscles from mice.
J Appl Physiol (1985). 2018 Feb 22. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study.
5
Ohmichi Y, Ohmichi M, Murai N, Yasui M, Takeshita N, Oshibuchi H, Naito M, Nakano T, Sato J.
Therapeutic effects of diclofenac, pregabalin, and duloxetine on disuse-induced chronic musculoskeletal pain in rats.
Sci Rep. 2018 Feb 19;8(1):3311.
https://www.ncbi.nlm.nih.gov/
Note: Cast immobilization was used. This article may be obtained online without charge.
6
Skals S, Vinstrup J, Sundstrup E, Jakobsen MD, Andersen CH, Andersen LL.
Shoulder and arm muscle activity during elastic band exercises performed in a hospital bed.
Phys Sportsmed. 2018 Feb 23. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
7
Hanaka M, Iba K, Dohke T, Kanaya K, Okazaki S, Yamashita T.
Antagonists to TRPV1, ASICs and P2X have a
potential role to prevent the triggering of regional bone metabolic
disorder and pain-like behavior in tail-suspended mice.
Bone. 2018 Feb 14. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study.
8
Mitchell JA, Chesi A, McCormack SE, Cousminer DL,
Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A,
Grant SFA, Zemel BS.
Physical activity and bone accretion: Isotemporal modeling and genetic interactions.
Med Sci Sports Exerc. 2018 Feb 20. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
9
Lee C, Jones TA.
Acute blockade of inner ear marginal and dark cell K(+) secretion: Effects on gravity receptor function.
Hear Res. 2018 Feb 13. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
10
Mahfuz MM, Schubert MC, Figtree WVC, Todd CJ, Khan SI, Migliaccio AA.
Optimal human passive vestibulo-ocular reflex adaptation does not rely on passive training.
J Assoc Res Otolaryngol. 2018 Feb 20. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
11
Gonfalone AA.
Sleep and gravity.
Med Hypotheses. 2018 Feb 22. [Epub ahead of print]
http://www.medical-hypotheses.
Note: This article may be obtained online without charge.
12
Dias RD, Ngo-Howard MC, Boskovski MT, Zenati MA, Yule SJ.
Systematic review of measurement tools to assess surgeons’ intraoperative cognitive workload.
Br J Surg. 2018 Feb 21. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
Note: The literature review found that the
NASA Task Load Index was the most commonly used self-reporting tool for
cognitive load assessment among surgeons.
13
Tubbs-Cooley HL, Mara CA, Carle AC, Gurses AP.
The NASA Task Load Index as a measure of overall workload among neonatal, paediatric and adult intensive care nurses.
Intensive Crit Care Nurs. 2018 Feb 12. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: From the introduction: “…in this paper
we evaluate the dimensionality and reliability of the NASA-TLX as a
measure of overall workload among ICU nurses.”
14
Yamani Y, McCarley JS.
Effects of task difficulty and display format on automation usage strategy: A workload capacity analysis.
Hum Factors. 2018 Feb 1. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
