NASA Spaceline Current Awareness List #783 26 January 2018 (Space Life Science Research Results)
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Papers deriving from NASA support:
1
Urbaniak C, Sielaff AC, Frey KG, Allen JE, Singh N, Jaing C, Wheeler K, Venkateswaran K.
Detection of antimicrobial resistance genes associated with the International Space Station environmental surfaces.
Sci Rep. 2018 Jan 16;8(1):814.
https://www.ncbi.nlm.nih.gov/
PIs:
K. Venkateswaran, C. Jaing
Note:
ISS results.
GeneLab: “The raw metagenomics sequences can be downloaded from the following GeneLab website (https://genelab-data.ndc.
This article may be obtained online without charge.
Journal Impact Factor:
4.259
Funding:
“This research was funded by a 2012 Space Biology NNH12ZTT001N grant
no. 19-12829-26
under Task Order NNN13D111T award to KV which also funded post-doctoral
fellowship for ACS, NS, and NASA Space Biology program sponsored NPP
post-doc for CU. This work was performed under the auspices of the U.S.
Department of Energy by Lawrence Livermore
National Laboratory under Contract DE-AC52-07NA27344. In addition, the
research carried out at Lawrence Livermore National Laboratory was
funded by a 2014 Space Biology NNH14ZTT002N grant no. NNX15AJ29G award
to CJ which also funded JEA.”
2
Patel N, Pass A, Mason S, Gibson CR, Otto C.
Optical
coherence tomography analysis of the optic nerve head and surrounding
structures in long-duration International Space Station Astronauts.
JAMA Ophthalmol. 2018 Jan 11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note:
ISS results. See the following citation for Invited Commentary: Lee AG,
Mader TH,
Gibson CR, Tarver W. Ocular coherence tomographic analysis of the optic
nerve head and surrounding structures in Space Flight-Associated
Neuro-ocular Syndrome. JAMA Ophthalmol. 2018 Jan 11.
https://www.ncbi.nlm.nih.gov/
Journal Impact Factor: 5.625
Funding:
“This study was supported by a KBRwyle subcontract. Drs Patel and Pass
were supported
by the University of Houston College of Optometry core facilities grant
NIH P30 EY007551 from the National Institutes of Health.”
3
Lee AG, Mader TH, Gibson CR, Tarver W.
Ocular
coherence tomographic analysis of the optic nerve head and surrounding
structures in Space Flight-Associated Neuro-ocular Syndrome.
JAMA Ophthalmol. 2018 Jan 11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note:
This
is an Invited Commentary on the previous citation: Patel N, Pass A,
Mason S, Gibson CR, Otto C. Optical coherence tomography analysis of the
optic nerve head and surrounding
structures in long-duration International Space Station astronauts.
JAMA Ophthalmol. 2018 Jan 11.
https://www.ncbi.nlm.nih.gov/
Journal Impact Factor:
5.625
Funding: No funding cited. “Drs Lee, Mader, Gibson, and Tarver report serving as employees
or consultants for National Aeronautics and Space Administration (NASA).”
4
Radford NB, DeFina LF, Leonard D, Barlow CE, Willis BL, Gibbons LW, Gilchrist SC, Khera A, Levine BD.
Cardiorespiratory
fitness, coronary artery calcium and cardiovascular disease events in a
cohort of generally healthy, middle aged men: Results from the Cooper
Center
Longitudinal Study.
Circulation. 2018 Jan 17. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: B.D. Levine
Journal Impact Factor:
19.309
Funding:
“This study was supported by the National Space Biomedical Research Institute through NASA NCC 9-58.”
5
McGinnis GJ, Raber J.
CNS side effects of immune checkpoint inhibitors: Preclinical models, genetics and multimodality therapy.
Immunotherapy. 2017 Sep;9(11):929-41.
https://www.ncbi.nlm.nih.gov/
PIs: J. Raber; M. Weil/J. Raber/NSCOR
Note: This article may be obtained online without charge.
Journal Impact Factor: 2.716
Funding:
“GJ
McGinnis is supported by an HHMI Medical Research Fellowship, the
Collins Medical Trust, an RSNA Research Medical Student Grant (RMS1416)
and the development account of J Raber.
The tumor models and radiation treatment in authors’ preclinical tumor
models were supported by NCI R01 CA182311 and an instrument grant from
the MJ Murdock Charitable Trust and the Providence Research Foundation.
For radiation studies, J Raber is supported
by NASA NNJ12ZSA001N and NNX15AK13G.”
6
Li
X, Baek G, Ramanand SG, Sharp A, Gao Y, Yuan W, Welti J, Rodrigues DN,
Dolling D, Figueiredo I, Sumanasuriya S, Crespo M, Aslam A, Li R, Yin Y,
Mukherjee B, Kanchwala
M, Hughes AM, Halsey WS, Chiang CM, Xing C, Raj GV, Burma S, de Bono J,
Mani RS.
BRD4 promotes DNA repair and mediates the formation of TMPRSS2-ERG gene rearrangements in prostate cancer.
Cell Rep. 2018 Jan 16;22(3):796-808.
https://www.ncbi.nlm.nih.gov/
PI:
S. Burma
Journal Impact Factor:
8.282
Funding:
“The authors acknowledge the assistance of the UT Southwestern Live
Cell Imaging
Facility, a Shared Resource of the Harold C. Simmons Cancer Center, is
supported in part by an NCI Cancer Center Support Grant (1P30
CA142543-01). NIH Pathway to Independence (PI) Award (R00CA160640) to
R.S.M. and startup funds from UT Southwestern supported
research reported in this publication. R.S.M. also acknowledges funding
from the ACS-IRG New Investigator Award in Cancer Research
(IRG-02-196), and from the Prostate Cancer Research Program (PCRP) –
Impact Award – US Department of Defense (W81XWH-17-1-0675).
J.d.B. (W81XWH-17-1-0676) and G.V.R. (W81XWH-17-1-0674) acknowledges
funding from the Prostate Cancer Research Program (PCRP) – Impact Award –
US Department of Defense. The authors acknowledge funding from Prostate
Cancer UK, the Prostate Cancer Foundation,
Movember, Stand Up To Cancer, the US Department of Defense, Cancer
Research UK, the UK Department of Health to the ICR/Royal Marsden ECMC,
the Academy of Medical Sciences, and NHS funding to the NIHR Biomedical
Research Centre at the Royal Marsden and The
Institute of Cancer Research. A.S. is supported by a Medical Research
Council fellowship. S.B. is supported by grants from the NIH
(RO1CA149461, RO1CA197796, and R21CA202403) and the National Aeronautics
and Space Administration (NNX16AD78G). C.-M.C. is supported
by grants from the NIH (CA103867), CPRIT (RP140367), and the Welch
Foundation (I-1805). C.X. was partially supported by NIH grant
UL1TR001105.”
7
Serrador JM, Deegan BM, Geraghty MC, Wood SJ.
Enhancing vestibular function in the elderly with imperceptible electrical stimulation.
Sci Rep. 2018 Jan 10;8(1):336.
https://www.ncbi.nlm.nih.gov/
PI:
J.M. Serrador
Note:
This article may be obtained online without charge.
Journal Impact Factor:
4.259
Funding:
“This work was supported by NASA (grant NNJ04HI13G), the Science Foundation Ireland Walton Visiting Fellow Award.”
______________________________
Other papers of interest:
1
Baio J, Martinez AF, Bailey LL, Hasaniya N, Pecaut M, Kearns-Jonker M.
Spaceflight
activates protein kinase C alpha signaling and modifies the
developmental stage of human neonatal cardiovascular progenitor cells.
Stem Cells Dev. 2018 Jan 10. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note:
ISS
results. Funding for this experiment was provided by the Center for
Advancement of Science in Space (Grant no. GA-2014-130 to MKJ).
2
Xu D, Gao Y, Guo L, Lin C, Sun Y.
Effect of
dys-1 mutation on gene expression profile in space-flown C. elegans.
Muscle Nerve. 2018 Jan 18. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Shenzhou-8 results.
3
Fischer J, Laforsch C.
The influence of gravity and light on locomotion and orientation of
Heterocypris incongruens and Notodromas monacha (Crustacea, Ostracoda).
npj Microgravity. 2018 Jan 18;4(1):3.
https://www.ncbi.nlm.nih.gov/
Note: Parabolic flight and TEXUS results. Clinorotation was used for ground-based experiments.
This article may be obtained online without charge.
4
Li W, Wang D, Wang D.
Regulation of the response of
Caenorhabditis elegans to simulated microgravity by p38 mitogen-activated protein kinase signaling.
Sci Rep. 2018 Jan 16;8(1):857.
https://www.ncbi.nlm.nih.gov/
Note:
The Synthecon Rotary System™ was used. This article may be obtained online without charge.
5
Mayorova TD, Smith CL, Hammar K, Winters CA, Pivovarova NB, Aronova MA, Leapman RD, Reese TS.
Cells containing aragonite crystals mediate responses to gravity in
Trichoplax adhaerens (Placozoa), an animal lacking neurons and synapses.
PLoS One. 2018 Jan 17;13(1):e0190905.
https://www.ncbi.nlm.nih.gov/
Note: A change in gravity was accomplished by tilting lab cover slips with attached animals
to 90°. This article may be obtained online without charge.
6
Hatzistergos KE, Jiang Z, Valasaki K, Takeuchi LM, Balkan W, Atluri P, Saur D, Seidler B, Tsinoremas N, DiFede D, Hare JM.
Simulated microgravity impairs cardiac autonomic neurogenesis from neural crest cells.
Stem Cells Dev. 2018 Jan 16. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note:
A
rotary cell suspension systems was used. Partially funded by “Award
#GA2014131 from the Center for the Advancement of Science in Space
(CASIS) to J.M.H.”
7
Kopp
S, Sahana J, Islam T, Petersen AG, Bauer J, Corydon TJ, Schulz H, Saar
K, Huebner N, Slumstrup L, Riwaldt S, Wehland M, Infanger M, Luetzenberg
R, Grimm D.
The role of NFκB in spheroid formation of human breast cancer cells cultured on the Random Positioning Machine.
Sci Rep. 2018 Jan 17;8(1):921.
https://www.ncbi.nlm.nih.gov/
Note:
A Random Positioning Machine was used. This article may be obtained online without charge.
8
He L, Chen Z, Wang S, Wu M, Setlow P, Li YQ.
Germination, outgrowth and vegetative growth kinetics of dry heat-treated individual spores of
Bacillus species.
Appl Environ Microbiol. 2018 Jan 12. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
9
Chang SF, Lin PC, Yang RS, Yang RJ.
The
preliminary effect of whole-body vibration intervention on improving
the skeletal muscle mass index, physical fitness, and quality of life
among older people with
sarcopenia.
BMC Geriatr. 2018 Jan 17;18(1):17.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
10
Kawao N, Moritake A, Tatsumi K, Kaji H.
Roles of irisin in the linkage from muscle to bone during mechanical unloading in mice.
Calcif Tissue Int. 2018 Jan 13. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note:
Hindlimb unloading was used.
11
Hara ES, Okada M, Nagaoka N, Hattori T, Iida LM, Kuboki T, Nakano T, Matsumoto T.
Chondrocyte burst promotes space for mineral expansion.
Integr Biol (Camb). 2018 Jan 22;10(1):57-66.
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb immobilization was used.
12
Allen B, Acharya MM, Lu C, Giedzinski E, Chmielewski N, Quach D, Hefferan M, Johe KK, Limoli CL.
Remediation of radiation-induced cognitive dysfunction through oral administration of the neuroprotective compound NSI-189.
Radiat Res. 2018 Jan 19. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
13
Alp M, Cucinotta FA.
Biophysics model of heavy-ion degradation of neuron morphology in mouse hippocampal granular cell layer neurons.
Radiat Res. 2018 Jan 18. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
14
Rudqvist N, Laiakis EC, Ghandhi SA, Kumar S, Knotts JD, Chowdhury M, Fornace AJ Jr, Amundson SA.
Global gene expression response in mouse models of DNA repair deficiency after gamma irradiation.
Radiat Res. 2018 Jan 19. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
15
Laurens J, Angelaki DE.
The brain compass: A perspective on how self-motion updates the head direction cell attractor.
Neuron. 2018 Jan 17;97(2):275-89.
https://www.ncbi.nlm.nih.gov/
16
Wei Y, Zheng J, So RHY.
Allocating less attention to central vision during vection is correlated with less motion sickness.
Ergonomics. 2018 Jan 11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
17
Lock J, Bearman C.
Normalization of deviation: Quotation error in human factors.
Hum Factors. 2018 Jan 1. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: From Methods: “A study was conducted examining quotation accuracy of 187 extracts
from 118 published articles that cited a control article (Vaughan’s 1996 book:
The Challenger Launch Decision: Risky Technology, Culture, and Deviance at NASA).”
18
Basner M, Dinges DF.
Sleep duration in the United States 2003-2016: First signs of success in the fight against sleep deficiency?
Sleep. 2018 Jan 8. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
19
Barger
LK, Runyon MS, Renn ML, Moore CG, Weiss PM, Condle JP, Flickinger KL,
Divecha AA, Coppler PJ, Sequeira DJ, Lang ES, Higgins JS, Patterson PD.
Effect
of fatigue training on safety, fatigue, and sleep in emergency medical
services personnel and other shift workers: A systematic review and
meta-analysis.
Prehosp Emerg Care. 2018 Jan 11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
20
Martin-Gill
C, Barger LK, Moore CG, Higgins JS, Teasley EM, Weiss PM, Condle JP,
Flickinger KL, Coppler PJ, Sequeira DJ, Divecha AA, Matthews ME, Lang
ES, Patterson PD.
Effects
of napping during shift work on sleepiness and performance in emergency
medical services personnel and similar shift workers: A systematic
review and meta-analysis.
Prehosp Emerg Care. 2018 Jan 11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note:
This article may be obtained online without charge.
21
Myers
JB, Wages RK, Rowe D, Nollette C, Touchstone M, Sinclair J, Mund EL,
Eberly JM, Montes JD, Sherlock RJ, Barger LK, Drummond SPA,
Gurubhagavatula I.
What an evidence-based guideline for fatigue risk management means for us: Statements from stakeholders.
Prehosp Emerg Care. 2018 Jan 11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note:
This article may be obtained online without charge.
