NASA Spaceline Current Awareness List #781 12 January 2018 (Space Life Science Research Results)
SPACELINE
Current Awareness Lists are distributed via listserv. Please send any
correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior
Editor,
rertwine@nasaprs.com.
Papers deriving from NASA support:
1
Zanello SB, Tadigotla V, Hurley J, Skog J, Stevens B, Calvillo E, Bershad E.
Inflammatory
gene expression signatures in idiopathic intracranial hypertension:
Possible implications in microgravity-induced ICP elevation.
npj Microgravity. 2018 Jan 11;4(1):1.
https://www.nature.com/
PI:
S.B. Zanello
Note:
This article may be obtained online without charge.
Journal Impact Factor:
Not available for this journal
Funding:
“This
material is based upon work supported by the National Aeronautics and
Space Administration under Grant/Contract/Agreement No NNX15AW48G to
SZ.”
2
Britten RA, Jewell JS, Duncan VD, Hadley MM, Macadat E, Musto AE, La Tessa C.
Impaired attentional set-shifting performance after exposure to 5 cGy of 600 MeV/n (28)Si particles.
Radiat Res. 2018 Jan 8. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: R.A. Britten
Journal Impact Factor: 2.539
Funding:
“This work was funded by NASA (grant nos. NNX11AC56G and NNX14AE73G).”
3
Shuryak I, Loucas BD, Cornforth MN.
Straightening
beta: Overdispersion of lethal chromosome aberrations following
radiotherapeutic doses leads to terminal linearity in the alpha-beta
model.
Front Oncol. 2017 Dec 21;7:318.
https://www.ncbi.nlm.nih.gov/
PIs: B. Loucas, M. Cornforth
Note:
This article may be obtained online without charge.
Journal Impact Factor:
Not available for this journal
Funding:
“This work supported by the following grants from the National
Aeronautics and
Space Administration (NASA): NNX15AG74G (MC) and NNX14AC76G (BL) and
from the National Institute of Allergy and Infectious Diseases (NIAID):
U19AI067773 (IS).”
4
Bhattacharya S, Asaithamby A.
Repurposing DNA repair factors to eradicate tumor cells upon radiotherapy.
Transl Can Res. 2017 Jul;6 Suppl 5:S822-S839. Review.
http://tcr.amegroups.com/
PIs:
A. Asaithamby, H. Sadek
Note: This article is part of a supplement to
Translational Cancer Research, “Focused Issue: Radiobiological
Models Towards a Personalized Radiation Oncology,” 2017 Jul; 6 Suppl 5.
The articles in this supplement may be obtained online without charge at
http://tcr.amegroups.com/
Journal Impact Factor:
1.757
Funding:
“The research in Asaithamby Aroumougame’s laboratory was partially
supported by
National Aeronautics and Space Administration (NNX13AD57G and
NNX15AE06G), Cancer Prevention and Research Institute of Texas
(RP160520), and National Institutes of Health (R01AG053341) grants.”
5
Cornforth M, Shuryak I, Loucas B.
Lethal
and nonlethal chromosome aberrations by gamma rays and heavy ions: A
cytogenetic perspective on dose fractionation in hadron radiotherapy.
Transl Can Res. 2017 Jul;6 Suppl 5:S769-S778.
http://tcr.amegroups.com/
PIs:
M. Cornforth, B. Loucas
Note: This article is part of a supplement to
Translational Cancer Research, “Focused Issue: Radiobiological
Models Towards a Personalized Radiation Oncology,” 2017 Jul; 6 Suppl 5.
The articles in this supplement may be obtained online without charge at
http://tcr.amegroups.com/
Journal Impact Factor:
1.757
Funding: “This was work supported by the following grants from the National Aeronautics
and Space Administration (NASA): NNX15AG74G (MC) and NNX14AC76G (BL).”
6
McKenna MJ, Bailey SM.
Chromosomal
and telomeric biomarkers of normal tissue injury to evaluate risk of
degenerative health effects (secondary malignancy, cardiovascular
disease) post radiation
therapy.
Transl Can Res. 2017 Jul;6 Suppl 5:S789-S794. Review.
http://tcr.amegroups.com/
PI: S.M. Bailey
Note: This article is part of a supplement to
Translational Cancer Research, “Focused Issue: Radiobiological
Models Towards a Personalized Radiation Oncology,” 2017 Jul; 6 Suppl 5.
The articles in this supplement may be obtained online without charge at
http://tcr.amegroups.com/
Journal Impact Factor:
1.757
Funding: “Support from NASA (NNX14AB02G; NNX14AH51G) is gratefully acknowledged.”
7
Ruttley TM, Robinson JA, Gerstenmaier WH.
The International Space Station: Collaboration, utilization, and commercialization.
Soc Sci Q. 2017 Dec;98(4):1160-74.
Note: This article is part of the “Selling Space” Special Issue of
Social Science Quarterly. For the remaining articles in the
issue, please see the Other papers of interest section, citations
14-20. This article may be obtained online without charge.
Journal Impact Factor:
0.849
Funding: No funding cited. T.M. Ruttley and J.A. Robinson are affiliated with NASA Johnson
Space Center; W.H. Gerstenmaier is affiliated with NASA Headquarters.
8
Balaraj VS, Zeng PC, Sanford SP, McBride SA, Raghunandan A, Lopez JM, Hirsa AH.
Surface shear viscosity as a macroscopic probe of amyloid fibril formation at a fluid interface.
Soft Matter. 2017 Mar 1;13(9):1780-7.
https://www.ncbi.nlm.nih.gov/
PI: A.H. Hirsa
Journal Impact Factor: 3.889
Funding:
“This work was supported by NASA grant NNX13AQ22G.”
9
Olafson KN, Nguyen TQ, Rimer JD, Vekilov PG.
Antimalarials inhibit hematin crystallization by unique drug-surface site interactions.
Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7531-6.
https://www.ncbi.nlm.nih.gov/
PI: P.G. Vekilov
Journal Impact Factor: 9.661
Funding:
“This
work was supported by NIH through the Nanobiology Interdisciplinary
Graduate Training Program of the Gulf Coast Consortia for Quantitative
Biomedical Sciences (Grant T32EB009379)
and directly (Grant 1R21AI126215-01), NASA (NNX14AD68G and NNX14AE79G),
and The Welch Foundation (Grant E-1794).”
10
Safari MS, Poling-Skutvik R, Vekilov PG, Conrad JC.
Differential dynamic microscopy of bidisperse colloidal suspensions.
npj Microgravity. 2017 Aug 30;3:21.
https://www.ncbi.nlm.nih.gov/
PI: P.G. Vekilov
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “This work was supported by NASA (NNX14AD68G to PGV and JCC), NSF (DMR-1151133,
to JCC), and the Welch Foundation (E-1869, to JCC).”
11
Yamazaki T, Kimura Y, Vekilov PG, Furukawa E, Shirai M, Matsumoto H, Van Driessche AE, Tsukamoto K.
Two types of amorphous protein particles facilitate crystal nucleation.
Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2154-9.
https://www.ncbi.nlm.nih.gov/
PI: P.G. Vekilov
Note:
This article may be obtained online without charge.
Journal Impact Factor: 9.661
Funding:
“This
work was supported by the Tohoku University Global Center of Excellence
Program for “Global Education and Research Center for Earth and
Planetary Dynamics,” by Grants-in-Aid
for Scientific Research for Research Activity Start-Up (26887001), for
Young Scientists (A) (24684033) and for Scientific Research (S)
(15H05731), and by the National Aeronautics and Space Administration
(Grants NNX14AE79G and NNX14AD68G) and the National
Science Foundation (Grant MCB-1518204). This work is partly supported
by the Sasakawa Scientific Research grant from the Japan Science Society
(28-232). The cryo-TEM observations were supported by the
Nanotechnology Platform Program of the Ministry of Education,
Culture, Sports, Science and Technology, Japan.”
______________________________
Other papers of interest:
1
Soga K, Wakabayashi K, Hoson T.
Growth and cortical microtubule dynamics in shoot organs under microgravity and hypergravity conditions.
Plant Signal Behav. 2017 Dec 29. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note:
ISS results. Centrifugation was used for hypergravity studies. From the
title page:
“Addendum to: Soga K, Yamazaki C, Kamada M, Tanigawa N, Kasahara H,
Yano S, Kojo KH, Kutsuna N, Kato T, Hashimoto T, Kotake T, Wakabayashi
K, Hoson T: Modification of growth anisotropy and cortical microtubule
dynamics in Arabidopsis hypocotyls grown under
microgravity conditions in space. Physiol Plant. 2018;162(1):xxx-xxx.
doi:10.1111/ppl.12640.” This citation appeared in SPACELINE Current
Awareness List #765, 15 Dep 2017.
2
Ratushnyy AY, Buravkova LB.
Expression of focal adhesion genes in mesenchymal stem cells under simulated microgravity.
Dokl Biochem Biophys. 2017 Nov;477(1):354-6.
https://www.ncbi.nlm.nih.gov/
Note:
A random positioning machine was used.
3
Zhang S, Wu Y, Weng Y, Xu Z, Chen W, Zheng D, Lin W, Liu J, Zhou Y.
In vitro growth of mouse preantral follicles under simulated microgravity.
J Vis Exp. 2017 Dec 17(130):55641.
https://www.ncbi.nlm.nih.gov/
Note: A Rotating Wall Vessel was used.
4
Fuchs FM, Raguse M, Fiebrandt M, Madela K, Awakowicz P, Laue M, Stapelmann K, Moeller R.
Investigating the detrimental effects of low pressure plasma sterilization on the survival of
Bacillus subtilis spores using live cell microscopy.
J Vis Exp. 2017 Nov 30(129):56666.
https://www.ncbi.nlm.nih.gov/
5
Aryankalayil MJ, Chopra S, Levin J, Eke I, Makinde A, Das S, Shankavaram U, Vanpouille-Box C, Demaria S, Coleman CN.
Radiation-induced long noncoding RNAs in a mouse model after whole-body irradiation.
Radiat Res. 2018 Jan 8. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
6
Raznitsyna I, Kulikova P, Rogatkin D, Kulikov D, Bychenkov O, Chursinova Y, Bobrov M, Glazkov A.
Fluorescence of radiation-induced tissue damage.
Int J Radiat Biol. 2018 Jan 3. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
7
Rusin A, Seymour C, Mothersill C.
Chronic
Fatigue and Immune Deficiency Syndrome (CFIDS), cellular metabolism,
and ionizing radiation: A review of contemporary scientific literature
and suggested directions
for future research.
Int J Radiat Biol. 2018 Jan 3. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
8
Castle KD, Chen M, Wisdom AJ, Kirsch DG.
Genetically engineered mouse models for studying radiation biology.
Transl Can Res. 2017 Jul;6 Suppl 5:S900-S913. Review.
http://tcr.amegroups.com/
Note: This article is part of a supplement to
Translational Cancer Research, “Focused Issue: Radiobiological
Models Towards a Personalized Radiation Oncology,” 2017 Jul; 6 Suppl 5.
The articles in this supplement may be obtained online without charge at
http://tcr.amegroups.com/
9
Dörr W, Herrmann T, Trott K-R.
Normal tissue tolerance.
Transl Can Res. 2017 Jul;6 Suppl 5:S840-S851. Review.
http://tcr.amegroups.com/
Note: This article is part of a supplement to
Translational Cancer Research, “Focused Issue: Radiobiological
Models Towards a Personalized Radiation Oncology,” 2017 Jul; 6 Suppl 5.
The articles in this supplement may be obtained online without charge at
http://tcr.amegroups.com/
10
Nickoloff JA, Boss M-K, Allen CP, LaRue SM.
Translational research in radiation-induced DNA damage signaling and repair.
Transl Can Res. 2017 Jul;6 Suppl 5:S875-S891. Review.
http://tcr.amegroups.com/
Note: This article is part of a supplement to
Translational Cancer Research, “Focused Issue: Radiobiological
Models Towards a Personalized Radiation Oncology,” 2017 Jul; 6 Suppl 5.
The articles in this supplement may be obtained online without charge at
http://tcr.amegroups.com/
11
Chen MM, Xu LH, Chang L, Yin P, Jiang ZL.
Reduction of motion sickness through targeting histamine N-methyltransferase in the dorsal vagal complex of the brain.
J Pharmacol Exp Ther. 2018 Jan 3. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note:
Rotation was used. This article may be obtained online without charge.
12
Peng HT, Bouak F, Wang W, Chow R, Vartanian O.
An improved model to predict performance under mental fatigue.
Ergonomics. 2018 Jan 8. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
13
Harkey AF, Watkins J, Olex AL, DiNapoli KT, Lewis D, Binder B, Fetrow JS, Muday GK.
Identification of transcriptional and receptor networks that control root responses to ethylene.
Plant Physiol. 2017 Dec 19. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note:
This article may be obtained online without charge.
Note: The following articles, as well as the article by Ruttley, et al. in the NASA section
(#6), are part of the Special Issue, Selling Space, published in the December 2017 issue of
Social Science Quarterly. From the Editor’s introduction: “The
articles in this special issue focus on different aspects of selling
science: What arguments does NASA use (or has used) to justify space
exploration? Are different programs justified differently?
How have these rationales changed over time? In part, our goal is to
understand how NASA is able to sustain research programs given
competition for federal funds—and to identify areas where it is unable
to do so. Addressing these questions will show how the
competition for funds shapes NASA’s research priorities. But more
generally, we believe that an understanding of NASA’s abilities to sell
science will help us make sense of the how the competition for funds
shapes scientific research more generally.” The issue
is available at:
http://onlinelibrary.wiley.
14
Bianco W, Gaddie K.
Special issue editors’ introduction: Selling space.
Soc Sci Q. 2017 Dec;98(4):1139-43.
http://onlinelibrary.wiley.
15
Bianco W, Gerhart D, Nicolson-Crotty S.
Waypoints for evaluating big science.
Soc Sci Q. 2017 Dec;98(4):1144-50.
http://onlinelibrary.wiley.
16
Bianco W, Schmidt E.
Knowing what we are getting: Evaluating scientific research on the International Space Station.
Soc Sci Q. 2017;98(4):1151-9.
http://onlinelibrary.wiley.
17
DeSante CD.
They chose to go to the Moon: How birth cohorts shape opinions on funding for space exploration.
Soc Sci Q. 2017 Dec;98(4):1175-88.
http://onlinelibrary.wiley.
18
Hayden JM, Geras MJ, Gerth NM, Crespin MH.
Land, wood, water, and space: Senator Robert S. Kerr, Congress, and selling the space race to the American public.
Soc Sci Q. 2017 Dec;98(4):1189-203.
http://onlinelibrary.wiley.
19
Alexander J.
Selling priorities in space science: The power of scientific community consensus.
Soc Sci Q. 2017;98(4):1204-15.
http://onlinelibrary.wiley.
20
Launius RD.
NASA’s quest for human spaceflight popular appeal.
Soc Sci Q. 2017 Dec;98(4):1216-32.
http://onlinelibrary.wiley.
