NASA Spaceline Current Awareness List #747 5 May 2017 (Space Life Science Research Results)
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Papers deriving from NASA support:
1
Morokuma J, Durant FR, Williams KB, Finkelstein JM, Blackiston DJ, Clements T, Reed DW, Roberts M, Jain M, Kimel K, Trauger SA, Wolfe BE, Levin M.
Planarian regeneration in space: Persistent anatomical, behavioral, and bacteriological changes induced by space travel.
Regeneration. 2017 Apr 26. [Article in Press]
http://onlinelibrary.wiley.
Note: ISS results. This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “This research was supported by the Allen Discovery Center program through The Paul G. Allen Frontiers Group (12171). M.L. also gratefully acknowledges support from the G. Harold and Leila Y. Mathers Charitable Foundation (TFU141), the W. M. Keck Foundation, and the National Science Foundation (IGERT DGE‐1144591).” D.W. Reed is affiliated with NASA Kennedy Space Center.
2
Turner RT, Philbrick KA, Kuah A, Branscum AJ, Iwaniec UT.
Role of oestrogen receptor signaling in skeletal response to leptin in female ob/ob mice.
J Endocrinol. 2017 Apr 20. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: R.T. Turner
Journal Impact Factor: 4.498
Funding: “This work was supported by grants from the NIH (AR060913), NASA (NNX12AL24G), and USDA (38420-17804).”
3
Suman S, Kumar S, Moon B-H, Fornace AJ Jr, Datta K.
Low and high dose rate heavy ion radiation-induced intestinal and colonic tumorigenesis in APC1838N/+ mice.
Life Sci Space Res. 2017 Apr 29. [Article in Press]
http://www.sciencedirect.com/
PIs: K. Datta; A.J. Fornace Jr/K. Datta/NSCOR
Journal Impact Factor: 1.97
Funding: “This study is supported by NASA Grant# NNX13AD58G and NNX15AI21G. We are thankful to Pelagie Ake for support with the mice breeding and animal husbandry.”
4
Xiao X, Hu M, Zhang X, Hu JZ.
NMR-based metabolomics analysis of liver from C57BL/6 mouse exposed to ionizing radiation.
Radiat Res. 2017 May 2. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: J.Z. Hu
Journal Impact Factor: 3.022
Funding: “This work was supported by the National Institute of Environmental Health Sciences of the National Institute of Health (NIH; award no. R01ES022176). Collection of the gamma and proton irradiated samples was supported by the NASA Space Radiation Program (grant no. NNX07AU44G).”
5
Flores-McLaughlin J, Runnells J, Gaza R.
Overview of non-ionizing radiation safety operations on the International Space Station.
J Space Safety Eng. 2017 Apr 28. [Article in Press]
http://www.jsse.space-safety.
Journal Impact Factor: Not available for this journal
Funding: No funding cited. The authors are affiliated with NASA Johnson Space Center.
6
Goel R, De Dios YE, Gadd NE, Caldwell EE, Peters BT, Reschke MF, Bloomberg JJ, Oddsson LIE, Mulavara AP.
Assessing somatosensory utilization during unipedal postural control.
Front Syst Neurosci. 2017 Apr 11;11:21.
https://www.ncbi.nlm.nih.gov/
PIs: A.P. Mulavara, J.J. Bloomberg
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “This study was supported in part by a grant from the National Space Biomedical Research Institute through NASA NCC9-58 to APM (PI, SA03801) and JJB (PI, SA02801) and by a grant from National Institute of Health to LIEO (PI, 5R21HD050655-02).”
7
Zhou M, Callaham JB, Reyes M, Stasiak M, Riva A, Zupanska AK, Dixon MA, Paul AL, Ferl RJ.
Dissecting low atmospheric pressure stress: Transcriptome responses to the components of hypobaria in Arabidopsis.
Front Plant Sci. 2017 Apr 10;8:528.
https://www.ncbi.nlm.nih.gov/
PIs: R.J. Ferl, A-L. Paul
Note: This article may be obtained online without charge.
Journal Impact Factor: 4.495
Funding: “This work was funded by grants NNX13AM46G and NNA04CC6 to RF and AP from NASA Space Life and Physical Sciences managed through Kennedy Space Center.”
______________________________
Other papers of interest:
1
Häder DP, Hemmersbach R.
Gravitaxis in Euglena.
Adv Exp Med Biol. 2017;979:237-66.
https://www.ncbi.nlm.nih.gov/
Note: Shuttle, parabolic flight, and TEXUS results. Studies discussed included the use of clinostats, random positioning machines, and centrifugation.
2
Häder DP, Iseki M.
Photomovement in Euglena.
Adv Exp Med Biol. 2017;979:207-35.
https://www.ncbi.nlm.nih.gov/
3
Häder D-P, Braun M, Grimm D, Hemmersbach R.
Gravireceptors in eukaryotes—a comparison of case studies on the cellular level.
npj Microgravity. 2017 Apr 28;3(1):13. Review.
https://www.nature.com/
Note: Studies discussed used centrifugation, clinostats, and random positioning machines. This article may be obtained online without charge.
4
Yoon N, Na K, Kim HS.
Simulated weightlessness affects the expression and activity of neuronal nitric oxide synthase in the rat brain.
Oncotarget. 2017 Feb 16. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study. This article may be obtained online without charge.
5
Kim YJ, Jeong AJ, Kim M, Lee C, Ye SK, Kim S.
Time-averaged simulated microgravity (taSMG) inhibits proliferation of lymphoma cells, L-540 and HDLM-2, using a 3D clinostat.
Biomed Eng Online. 2017 Apr 20;16(1):48.
https://www.ncbi.nlm.nih.gov/
Note: A 3D clinostat was used. This article may be obtained online without charge.
6
Na K, Kim HS.
Adrenalectomy abolishes hypergravity-induced gastric acid hyposecretion.
Oncotarget. 2017 Feb 16. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Centrifugation was used. This article may be obtained online without charge.
7
Vinstrup J, Skals S, Calatayud J, Jakobsen MD, Sundstrup E, Pinto MD, Izquierdo M, Wang Y, Zebis MK, Andersen LL.
Electromyographic evaluation of high-intensity elastic resistance exercises for lower extremity muscles during bed rest.
Eur J Appl Physiol. 2017 Apr 26. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Bed rest study.
8
Li B, Liu J, Zhao J, Ma JX, Jia HB, Zhang Y, Xing GS, Ma XL.
LncRNA-H19 modulates Wnt/β-catenin signaling by targeting Dkk4 in hindlimb unloaded rat.
Orthop Surg. 2017 Apr 26. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study.
9
Styner M, Pagnotti GM, McGrath C, Wu X, Sen B, Uzer G, Xie Z, Zong X, Styner MA, Rubin CT, Rubin J.
Exercise decreases marrow adipose tissue though β-oxidation in obese running mice.
J Bone Miner Res. 2017 Apr 24. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
10
Adamatzky A, Sirakoulis GC, Martínez GJ, Baluška F, Mancuso S.
On plant roots logical gates.
Biosystems. 2017 Apr 17;156-157:40-5. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: In collision-based computation, theoretical constructs of logical gates are implemented with plant roots; gravitropism is presented as a gate.
11
Sun J, Wang L, Li S, Yin L, Huang J, Chen C.
Toxicity of silver nanoparticles to Arabidopsis: Inhibition of root gravitropism by interfering with auxin pathway.
Environ Toxicol Chem. 2017 Apr 25. [Epub ahead of print]
