Status Report

NASA Spaceline Current Awareness List #693 8 April 2016

By SpaceRef Editor

April 8, 2016

Filed under ISS, Spaceline, Spaceline Current Awareness, US

Editor’s note: NASA’s various life sciences programs have prepared the SPACELINE Current Awareness updates since 1999 covering all aspects of space life science, gravitational biology, space medicine, and human factors. NASA does not maintain a website – nor does it have an archive of this resource online. However, SpaceRef does have a complete archive of SPACELINE updates all the way back to 1999 that can be accessed here: http://www.spaceref.com/news/mission.html?mid=188&page=1

Papers deriving from NASA support:

Eckberg DL, Diedrich A, Cooke WH, Biaggioni I, Buckey JC Jr., Pawelczyk JA, Ertl AC, Cox JF, Kuusela TA, Tahvanainen KU, Mano T, Iwase S, Baisch FJ, Levine BD, Adams-Huet B, Robertson D, Blomqvist CG.

Respiratory modulation of human autonomic function. Long-term neuroplasticity in space.

J Physiol. 2016 Mar 29. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27029027

PI: D.L. Eckberg

Note: Neurolab mission STS-90 results.

Journal Impact Factor: 5.037

Funding: “This work was supported by National Aeronautics and Space Administration contracts NAS0-19541 and NAG2-408, National Heart, Lung, and Blood Institute, UO1HL-56417. It was also supported by a grant from the Centennial Foundation of Helsingin Sanomat, Finland.”

Eckberg DL, Cooke WH, Diedrich A, Biaggioni I, Buckey JC Jr., Pawelczyk JA, Ertl AC, Cox JF, Kuusela TA, Tahvanainen KU, Mano T, Iwase S, Baisch FJ, Levine BD, Adams-Huet B, Robertson D, Blomqvist CG.

Respiratory modulation of human autonomic function on Earth.

J Physiol. 2016 Mar 29. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27028958

PI: D.L. Eckberg

Note: This is a companion to the preceding article, Eckberg DL, Diedrich A, Cooke WH, et al. Respiratory modulation of human autonomic function. Long-term neuroplasticity in space. J Physiol. 2016 Mar 29. http://www.ncbi.nlm.nih.gov/pubmed/27029027.

Journal Impact Factor: 5.037

Barcellos-Hoff MH, Mao JH.

HZE radiation non-targeted effects on the microenvironment that mediate mammary carcinogenesis.

Front Oncol. 2016 Mar 11;6:57.

http://www.ncbi.nlm.nih.gov/pubmed/27014632

PI: M.H. Barcellos-Hoff

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “NNX13AF06G, Barcellos-Hoff, Mary Helen: 10/01/2012–01/30/2016. National Aeronautics and Space Agency: HZE radiation effects on malignant progression in human epithelial cells.”

Huang L, Wickramasekara SI, Akinyeke T, Stewart BS, Jiang Y, Raber J, Maier CS.

Ion mobility-enhanced MS-based label-free analysis reveals effects of low-dose radiation post contextual fear conditioning training on the mouse hippocampal proteome.

J Proteomics. 2016 Mar 25. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27020882

PIs: J. Raber; G.A. Nelson/J. Raber/NSCOR

Journal Impact Factor: 3.888

Funding: “This work was supported in part by NIH grants P30ES000210, S10RR025628, and T32AA007468, NASA Grants #NNX10AD59G and #NNJ12ZSA001N and the development account of Dr. Raber.”

Bermudez EB, Klerman EB, Czeisler CA, Cohen DA, Wyatt JK, Phillips AJ.

Prediction of vigilant attention and cognitive performance using self-reported alertness, circadian phase, hours since awakening, and accumulated sleep loss.

PLoS One. 2016 Mar 28;11(3):e0151770.

http://www.ncbi.nlm.nih.gov/pubmed/27019198

PI: E.B. Klerman

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.234

Funding: “This work supported was by the National Space Biomedical Research Institute (NSBRI, www.nsbri.org) HFP02802 (AJKP, EBB, EBK) and a NSBRI grant to Morehouse Medical School (EBB) through NASA Cooperative Agreement NCC 9-58; the National Institutes of Health (NIH, www.nih.gov) awards K24-HL105664 (EBK), K99-HL119618 (AJKP), R00-HL119618 (AJKP), NCC-9-58-24, P01-AG009975, RC2-HL101340, R01-HL114088, and T32- HLO7901 (EBB), plus grants supporting the original experimental work.”

Choi WG, Hilleary R, Swanson SJ, Kim SH, Gilroy S.

Rapid, long-distance electrical and calcium signaling in plants.

Annu Rev Plant Biol. 2016 Mar 17. [Epub ahead of print] Review.

http://www.ncbi.nlm.nih.gov/pubmed/27023742

PI: S. Gilroy

Journal Impact Factor: 23.300

Funding: “We gratefully acknowledge the support of the National Science Foundation and NASA.”

______________________________________________________

Other papers of interest:

Coil DA, Neches RY, Lang JM, Brown WE, Severance M, Cavalier D, Eisen JA.

Growth of 48 built environment bacterial isolates on board the International Space Station (ISS).

PeerJ. 2016 Mar 22;4:e1842.

http://www.ncbi.nlm.nih.gov/pubmed/27019789

Note: ISS results. This article may be obtained online without charge.

Terada M, Seki M, Takahashi R, Yamada S, Higashibata A, Majima HJ, Sudoh M, Mukai C, Ishioka N.

Effects of a closed space environment on gene expression in hair follicles of astronauts in the International Space Station.

PLoS One. 2016 Mar 30;11(3):e0150801.

http://www.ncbi.nlm.nih.gov/pubmed/27029003

Note: ISS results. This article may be obtained online without charge.

Hallgren E, Kornilova L, Fransen E, Glukhikh D, Moore ST, Clément G, Van Ombergen A, MacDougall HG, Naumov I, Wuyts FL.

Decreased otolith-mediated vestibular response in 25 astronauts induced by long duration spaceflight.

J Neurophysiol. 2016 Mar 23:jn.00065.2016. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27009158

Note: ISS results. Astronauts were tested with centrifugation before and after 6-month stays on ISS.

Hunter SK.

The relevance of sex differences in performance fatigability.

Med Sci Sports Exerc. 2016 Mar 25. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27015385

Hinojosa-Laborde C, Howard JT, Mulligan J, Grudic GZ, Convertino VA.

Comparison of compensatory reserve during lower body negative pressure and hemorrhage in non-human primates.

Am J Physiol Regul Integr Comp Physiol. 2016 Mar 30:ajpregu.00304.2015. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27030667

Marshall-Goebel K, Ambarki K, Eklund A, Malm J, Mulder E, Gerlach D, Bershad E, Rittweger J.

Effects of short-term exposure to head down tilt on cerebral hemodynamics: A prospective evaluation of a space-flight analog using phase contrast MRI.

J Appl Physiol (1985). 2016 Mar 24:jap.00841.2015. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27013606

Note: Bed rest study. From the Abstract: “This is the first study to examine cerebral hemodynamics using phase contrast MRI during various angles of head down tilt. Further, the study investigated the additional effects of increased ambient carbon dioxide during head down tilt as an analog to the environment onboard the International Space Station.”

Jaki Mekjavic P, Lenassi E, Eiken O, Mekjavic IB.

Effect of acute hypercapnia during 10-d hypoxic bed rest on posterior eye structures.

J Appl Physiol (1985). 2016 Mar 24:jap.00930.2015. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27013607

Note: Bed rest study.

Toma S, Lacquaniti F.

Mapping muscles activation to force perception during unloading.

PLoS One. 2016 Mar 31;11(3):e0152552.

http://www.ncbi.nlm.nih.gov/pubmed/27032087

Note: Arm muscles were unloaded using the Trackhold device. This article may be obtained online without charge.

Zhou J, Liu B, Liang C, Li Y, Song YH.

Cytokine signaling in skeletal muscle wasting.

Trends Endocrinol Metab. 2016 Mar 26. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27025788

Hambli R, Boughattas MH, Daniel JL, Kourta A.

Prediction of denosumab effects on bone remodeling: A combined pharmacokinetics and finite element modeling.

J Mech Behav Biomed Mater. 2016 Mar 18;60:492-504. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27026666

Matsumoto Y, Tousen Y, Nishide Y, Tadaishi M, Kato K, Ishimi Y.

Combined effects of soy isoflavones and milk basic protein on bone mineral density in hind-limb unloaded mice.

J Clin Biochem Nutr. 2016 Mar;58(2):141-5. Epub 2016 Jan 22.

http://www.ncbi.nlm.nih.gov/pubmed/27013781

Note: Hindlimb unloading study. This article may be obtained online without charge.

Reinberg A, Smolensky MH, Touitou Y.

The full moon as a synchronizer of circa-monthly biological rhythms: Chronobiologic perspectives based on multidisciplinary naturalistic research.

Chronobiol Int. 2016 Mar 28:1-15. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27019304

Note: From the Introduction: “The aim of this editorial is to call attention to the significance of the ~30-day (lunar) cycle of moonlight on the chronobiology of life forms, including humans, which seems to be underappreciated or dismissed because of ancient myths, poor research methods, or other reasons.”

Chen A, Gu Y, Liu S, DeAngelis GC, Angelaki DE.

Evidence for a causal contribution of Macaque vestibular, but not intraparietal, cortex to heading perception.

J Neurosci. 2016 Mar 30;36(13):3789-98.

http://www.ncbi.nlm.nih.gov/pubmed/27030763

Schönherr A, May CA.

Influence of caloric vestibular stimulation on body experience in healthy humans.

Front Integr Neurosci. 2016 Mar 11;10:14.

http://www.ncbi.nlm.nih.gov/pubmed/27013995

Note: From the Introduction: “The main question leading to the present study concerned the role of the vestibular system on body experience in healthy participants. Our study focuses on the influence of CVS on the four different components of one’s total body experience (perceptive, cognitive, affective and behavioral).” This article may be obtained online without charge.

Arnal PJ, Lapole T, Erblang M, Guillard M, Bourrilhon C, Leger D, Chennaoui M, Millet GY.

Sleep extension before sleep loss: Effects on performance and neuromuscular function.

Med Sci Sports Exerc. 2016 Mar 25. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27015382

Sullivan S, Hart JE, Rasch P, Walker CH, Christie JM.

Phytochrome A mediates blue-light enhancement of second-positive phototropism in Arabidopsis.

Front Plant Sci. 2016 Mar 11;7:290.

http://www.ncbi.nlm.nih.gov/pubmed/27014313

Note: This article may be obtained online without charge.

Vinterhalter D, Savić J, Stanišić M, Jovanović Ž, Vinterhalter B.

Interaction with gravitropism, reversibility and lateral movements of phototropically stimulated potato shoots.

J Plant Res. 2016 Mar 31. [Epub ahead of print]