Status Report

NASA Spaceline Current Awareness List #678 18 December 2015

By SpaceRef Editor

December 18, 2015

Filed under ISS, Spaceline, Spaceline Current Awareness, US

Please note: The next issue of SPACELINE Current Awareness (List #679) will be sent on Monday, January 4, 2016.

Papers deriving from NASA support:

Ramaswamy V, Dirr E, Allen J.

The effect of simulated microgravity on differentiation of porcine blood derived vascular stem cells.

Stem Cells Dev. 2015 Dec 9. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26649474

PI: J. Allen

Note: A rotating wall vessel was used.

Journal Impact Factor: 3.727

Funding: “This work is funded by National Aeronautics and Space Administration, Fundamental Space Biology Division, grant to J. Allen Grant# NNX13AM03G.”

Sishc BJ, Nelson CB, McKenna MJ, Battaglia CL, Herndon A, Idate R, Liber HL, Bailey SM.

Telomeres and telomerase in the radiation response: Implications for instability, reprograming, and carcinogenesis.

Front Oncol. 2015 Nov 24;5:257.

http://www.ncbi.nlm.nih.gov/pubmed/26636039

PI: S.M. Bailey

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “Support for this research from NASA (NNX08AB656 [NNX08AB65G – Ed.]; NNX14AB02G; NNX14AH51G) is also gratefully acknowledged.”

Ramadan SS, Sridharan V, Koturbash I, Miousse IR, Hauer-Jensen M, Nelson GA, Boerma M.

A priming dose of protons alters the early cardiac cellular and molecular response to 56Fe irradiation.

Life Sci Space Res. 2016 Dec 14. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552415000991

PIs: G.A. Nelson/NSCOR; M. Boerma/I. Koturbash/M. Hauer-Jensen/G.A. Nelson/NSBRI Center for Research on Cardiac, Vascular, and Acute Effects of Space Radiation

Journal Impact Factor: 1.183

Funding: “This work was supported by National Aeronautics and Space Administration [NNX10AD59G to GN], the National Space Biomedical Research Institute [RE03701 through NCC 9-58 to MB], the National Institutes of Health [CA148679 to MB and Clinical and Translational Science Award UL1TR000039 and KL2TR000063 to IK], and the Arkansas Biosciences Institute [to IK].”

Plante I, Devroye L.

On the Green’s function of the partially diffusion-controlled reversible ABCD reaction for radiation chemistry codes.

J Comput Phys. 2015 Sep 15;297:515-29.

http://www.sciencedirect.com/science/article/pii/S0021999115003253

PI: S. Blattnig

Journal Impact Factor: 2.434

Funding: “This work was supported by the National Aeronautics and Space Administration (NASA) Bioastronautics Contract NAS9-02078.” I. Plante is funded through the NASA Space Radiation Risk Assessment Project.

Davis CM, Roma PG, Hienz RD.

A rodent model of the human psychomotor vigilance test: Performance comparisons.

J Neurosci Methods. 2015 Nov 27. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26639896

PIs: C.M. Davis, R.D. Hienz

Journal Impact Factor: 2.025

Funding: “This research was supported by the National Space Biomedical Research Institute (NSBRI) through NASA cooperative agreement NCC 9-58, grants NBPF01604, NBPF02802, NBPF04201, PF02602 and EO00010, and NASA NNX15AC71G.” EO00010 is an NSBRI Career Development Award to Dr. Davis.

Muralidharan S, Sasi SP, Zuriaga MA, Hirschi KK, Porada CD, Coleman MA, Walsh KX, Yan X, Goukassian DA.

Corrigendum: Ionizing particle radiation as a modulator of endogenous bone marrow cell reprogramming: Implications for hematological cancers.

Front Oncol. 2015 Nov 25;5:255.

http://www.ncbi.nlm.nih.gov/pubmed/26636037

PI: D.A. Goukassian

Note: From the authors: “In the paper titled “Ionizing particle radiation as a modulator of endogenous bone marrow cell reprogramming: Implications for hematological cancers,” there was [a] secretarial error made at our end in “Figure 1,” which should be corrected. At some point of the submission in Figure 1, A and B were disarranged in the slide. No other correction is needed as the text and figure legends are correct.” The original article appeared in Current Awareness List #673, 13 November 2015, http://www.ncbi.nlm.nih.gov/pubmed/26528440. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: From original article: “This work was supported by the National Aeronautics and Space Administration (NASA) under Grant No. NNX11AD22G and American Heart Association (AHA) under Grant No. 14GRNT18860032 to DAG and NASA Grant No. NNX13AB67G to CDP.”

______________________________________________________

Other papers of interest:

Sun S, Henriksen K, Karsdal MA, Byrjalsen I, Rittweger J, Armbrecht G, Belavy DL, Felsenberg D, Nedergaard AF.

Collagen type III and VI turnover in response to long-term immobilization.

PLoS One. 2015 Dec 7;10(12):e0144525.

http://www.ncbi.nlm.nih.gov/pubmed/26641456

Note: Bed rest study. This article may be obtained online without charge.

Pavei G, Minetti AE.

Hopping locomotion at different gravity: Metabolism and mechanics in humans.

J Appl Physiol (1985). 2015 Dec 3:jap.00839.2015. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26635350

Note: Altered gravity was achieved through use of bungee jumping bands, a pulley, and an electric winch to control body suspension.

Szulcek R, van Bezu J, Boonstra J, van Loon JJ, van Nieuw Amerongen GP.

Transient intervals of hyper-gravity enhance endothelial barrier integrity: Impact of mechanical and gravitational forces measured electrically.

PLoS One. 2015 Dec 4;10(12):e0144269.

http://www.ncbi.nlm.nih.gov/pubmed/26637177

Note: A Large Diameter Centrifuge and a random positioning machine were used. This article may be obtained online without charge.

Pierce NE, Parell GJ, Jesus RO, Ojano-Dirain CP, Antonelli PJ.

Magnetic resonance imaging in a guinea pig model of inner ear decompression sickness and barotrauma.

Laryngoscope. 2015 Dec 9. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26649994

Cronin WA, Senese AL, Arnaud FG, Regis DP, Auker CR, Mahon RT.

The effect of the perfluorocarbon emulsion Oxycyte on platelet count and function in the treatment of decompression sickness in a swine model.

Blood Coagul Fibrinolysis. 2015 Dec 8. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26650458

Jang TY, Chang GU, Kim K-S, Heo M-J, Jung A-Y, Kim YH.

Three weeks of anti-orthostatic suspension had no effect on immune status in a specific-pathogen-free environment.

Microgravity Sci Technol. 2015 Sep;27(5):321-7.

http://link.springer.com/article/10.1007/s12217-015-9418-0

Note: Hindlimb unloading study.

Gianelo MC, Polizzelo JC, Chesca D, Mattiello-Sverzut AC.

Three days of intermittent stretching after muscle disuse alters the proteins involved in force transmission in muscle fibers in weanling rats.

Braz J Med Biol Res. 2016;49(2). Epub 2015 Dec 4.

http://www.ncbi.nlm.nih.gov/pubmed/26648091

Note: Hindlimb immobilization was used. This article may be obtained online without charge.

Sun KT, Leung KS, Siu PM, Qin L, Cheung WH.

Differential effects of low-magnitude high-frequency vibration on reloading hind-limb soleus and gastrocnemius medialis muscles in 28-day tail-suspended rats.

J Musculoskelet Neuronal Interact. 2015 Dec;15(4):316-24.

http://www.ncbi.nlm.nih.gov/pubmed/26636277

Note: Hindlimb unloading study. This article may be obtained online without charge.

Vigotsky AD, Contreras B, Beardsley C.

Biomechanical implications of skeletal muscle hypertrophy and atrophy: A musculoskeletal model.

PeerJ. 2015 Nov 30;3:e1462.

http://www.ncbi.nlm.nih.gov/pubmed/26644989

Note: This article may be obtained online without charge.

Polley KR, Jenkins N, O’Connor P, McCully K.

Influence of exercise training with resveratrol supplementation on skeletal muscle mitochondrial capacity.

Appl Physiol Nutr Metab. 2015 Sep 11:1-7. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26638911

Versari S, Barenghi L, van Loon J, Bradamante S.

The SCD Stem Cell Differentiation ESA Project: Preparatory work for the spaceflight mission.

Microgravity Sci Technol. 2015 Nov 12:1-10. [Article in Press]

http://link.springer.com/article/10.1007%2Fs12217-015-9466-5#

Note: Planned ISS experiment; now onboard ISS. This article may be obtained online without charge.

Park JH, Seo D-H, Cho S, Kim S-H, Eom S, Kim HS.

Effects of partial vibration on morphological changes in bone and surrounding muscle of rats under microgravity condition: Comparative study by gender.

Microgravity Sci Technol. 2015 Sep;27(5):361-8.

http://link.springer.com/article/10.1007/s12217-015-9425-1

Note: Hindlimb unloading study.

Chen G, Yang L, Lv Y.

Cell-free scaffolds with different stiffness but same microstructure promote bone regeneration in rabbit large bone defect model.

J Biomed Mater Res A. 2015 Dec 9. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26650620

Rhm W, Woloschak GE, Shore RE, Azizova TV, Grosche B, Niwa O, Akiba S, Ono T, Suzuki K, Iwasaki T, Ban N, Kai M, Clement CH, Bouffler S, Toma H, Hamada N.

Dose and dose-rate effects of ionizing radiation: A discussion in the light of radiological protection.

Radiat Environ Biophys. 2015 Nov;54(4):379-401. Epub 2015 Sep 5.

http://www.ncbi.nlm.nih.gov/pubmed/26343037

Baier B, Vogt T, Rohde F, Cuvenhaus H, Conrad J, Dieterich M.

Deep brain stimulation of the nucleus ventralis intermedius: A thalamic site of graviceptive modulation.

Brain Struct Funct. 2015 Dec 9. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26650047

Wang H, Li X, Krause L, Grg M, Schler O, Hauslage J, Hemmersbach R, Kircher S, Lasok H, Haser T, Rapp K, Schmidt J, Yu X, Pasternak T, Aubry-Hivet D, Tietz O, Dovzhenko A, Palme K, Ditengou FA.

2-D clinostat for simulated microgravity experiments with Arabidopsis seedlings.

Microgravity Sci Technol. 2015:1-8. Epub 2015 Dec 12.

http://link.springer.com/article/10.1007/s12217-015-9478-1

Note: A 2-D clinostat was used.

Kamal KY, Herranz R, van Loon JJWA, Christianen PCM, Medina FJ.

Evaluation of simulated microgravity environments induced by diamagnetic levitation of plant cell suspension cultures.

Microgravity Sci Technol. 2015 Nov 20:1-9. [Article in Press]

http://link.springer.com/article/10.1007/s12217-015-9472-7

Note: Magnetic levitation was used.

Hellweg CE, Spitta LF, Kopp K, Schmitz C, Reitz G, Gerzer R.

Evaluation of an international doctoral educational program in space life sciences: The Helmholtz Space Life Sciences Research School (SpaceLife) in Germany.

Adv Space Res. 2016 Jan;57(1):378-97.

http://www.sciencedirect.com/science/article/pii/S0273117715007589

Smith CM.

An adaptive paradigm for human space settlement.

Acta Astronaut. 2016 Feb;119:207-17.

http://www.sciencedirect.com/science/article/pii/S0094576515004233