Status Report

NASA Spaceline Current Awareness List #676 4 December 2015

By SpaceRef Editor

December 4, 2015

Filed under ISS, Spaceline, Spaceline Current Awareness, US

Papers deriving from NASA support:

Hackney KJ, Scott JM, Hanson AM, English KL, Downs ME, Ploutz-Snyder LL.

The astronaut-athlete: Optimizing human performance in space.

J Strength Cond Res. 2015 Dec;29(12):3531-45. Review.

http://www.ncbi.nlm.nih.gov/pubmed/26595138

PI: L.L. Ploutz-Snyder

Note: ISS and Shuttle results. This article may be obtained online without charge.

Journal Impact Factor: 2.075

Funding: “This work was partially funded by North Dakota NASA Experimental Program to Stimulate Competitive Research (EPSCoR) to K. J. Hackney.” The PI also acknowledges both NSBRI and NASA for funding that contributed to ideas expressed in the paper.

Zhang C, Brown MQ, van de Ven W, Zhang ZM, Wu B, Young MC, Synek L, Borchardt D, Harrison R, Pan S, Luo N, Huang YM, Ghang YJ, Ung N, Li R, Isley J, Morikis D, Song J, Guo W, Hooley RJ, Chang CA, Yang Z, Zarsky V, Muday GK, Hicks GR, Raikhel NV.

Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis.

Proc Natl Acad Sci U S A. 2015 Nov 25. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26607451

PI: G.K. Muday

Note: This article may be obtained online without charge.

Journal Impact Factor: 9.674

Funding: “US Department of Energy Grant DE-FG02-02ER15295 provided financial support (to N.V.R. and G.R.H.). The National Aeronautics and Space Administration provided financial support with Grant NNX09AK82G (to G.K.M.). Grantová Agentura České Republiky/Czech Science Foundation Project 15-14886S and Ministerstvo Školství, Mládeže a Tělovýchovy České Republiky Project NPUI LO1417 provided support (to V.Z.).”

Boothby TC, Tenlen JR, Smith FW, Wang JR, Patanella KA, Osborne Nishimura E, Tintori SC, Li Q, Jones CD, Yandell M, Messina DN, Glasscock J, Goldstein B.

Evidence for extensive horizontal gene transfer from the draft genome of a tardigrade.

Proc Natl Acad Sci U S A. 2015 Nov 23. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26598659

PI: T.C. Boothby

Journal Impact Factor: 9.674

Funding: “This work was funded by National Science Foundation Grant IOS 1257320 (to B.G.), National Aeronautics and Space Administration Grant 14-14SF_Step2-0019 [NNX15AB44G] (to T.C.B.), National Institute of General Medical Science Grant K12GM000678 (to J.R.T.), and North Carolina Biotechnology Center Grant 2013-MRG-1110 (to C.D.J.), and by contributions from the University of North Carolina at Chapel Hill’s Integrative Program for Biological and Genome Sciences, Carolina Center for Genome Sciences, and Office of the Vice Chancellor for Research.”

Govey PM, Kawasawa YI, Donahue HJ.

Mapping the osteocytic cell response to fluid flow using RNA-Seq.

J Biomech. 2015 Nov 5. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26573903

PI: H.J. Donahue

Journal Impact Factor: 2.751

Funding: “This work was supported by 9R01AR068132-15 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health.” The PI reports funding by NSBRI.

Hurst VW, Peterson S, Garcia K, Ebert D, Ham D, Amponsah D, Dulchavsky S.

Concept of operations evaluation for using remote-guidance ultrasound for exploration spaceflight.

Aerosp Med Hum Perform. 2015 Dec;86(12):1034-8.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/00000012/art00006

Journal Impact Factor: 0.875

Funding: “The work for this study was performed in the Space Medicine Division at NASA JSC under National Space Biomedical Research Institute contract # L69030 with Wyle.”

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Aerospace Medicine and Human Performance has published a supplement – “Exercise Countermeasures: The First Decade on ISS,” a collaborative effort of the International Counter-measures Working Group. Judith Hayes notes in her introductory article that the principal objective of the supplement is “to document the operational ISS exercise countermeasures system and the associated health outcomes of astronauts and cosmonauts during Expeditions 1-25. . .[the] supplement describes events, records lessons learned, and assesses biomedical results obtained during the first decade of ISS.” The articles are available free of charge at http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/a00112s1;jsessionid=81ft2l0bf48q.alice.

Hayes J.

The first decade of ISS exercise: Lessons learned on Expeditions 1-25.

Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A1-A6.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/A00112s1/art00003

Korth DW.

Exercise countermeasure hardware evolution on ISS: The first decade.

Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A7-A13.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/A00112s1/art00004

Loehr JA, Guilliams ME, Petersen N, Hirsch N, Kawashima S, Ohshima H.

Physical training for long-duration spaceflight.

Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A14-A23.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/A00112s1/art00005

Kozlovskaya IB, Yarmanova EN, Yegorov AD, Stepantsov VI, Fomina EV, Tomilovaskaya ES.

Russian countermeasure systems for adverse effects of microgravity on long-duration ISS flights.

Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A24-A31.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/A00112s1/art00006

Yarmanova EN, Kozlovskaya IB, Khimoroda NN, Fomina EV.

Evolution of Russian microgravity countermeasures.

Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A32-A37.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/A00112s1/art00007

Sibonga JD, Spector ER, Johnston SL, Tarver WJ.

Evaluating bone loss in ISS astronauts.

Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A38-A44.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/A00112s1/art00008

Wood SJ, Paloski WH, Clark JB.

Assessing sensorimotor function following ISS with computerized dynamic posturography.

Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A45-A53.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/A00112s1/art00009

Lee SMC, Feiveson AH, Stein S, Stenger MB, Platts SH.

Orthostatic intolerance after ISS and Space Shuttle Missions.

Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A54-A67.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/A00112s1/art00010

English KL, Lee SMC, Loehr JA, Ploutz-Snyder RJ, Ploutz-Snyder LL.

Isokinetic strength changes following long-duration spaceflight on the ISS.

Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A68-A77.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/A00112s1/art00011

Moore AD Jr, Lynn PA, Feiveson AH.

The first 10 years of aerobic exercise responses to long-duration ISS flights.

Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A78-A86.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/A00112s1/art00012

Laughlin MS, Guilliams ME, Nieschwitz BA, Hoellen D.

Functional fitness testing results following long-duration ISS missions.

Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A87-A91.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/A00112s1/art00013

Loerch LH.

Exercise countermeasures on ISS: Summary and future directions.

Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A92-A94.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/A00112s1/art00014

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Other papers of interest:

Convertino VA.

Career perspective: Victor A. Convertino.

Extrem Physiol Med. 2015 Nov 19;4:21.

http://www.ncbi.nlm.nih.gov/pubmed/26587224

Note: The author reviews his work with NASA in exercise and physiology research and in acute and chronic physiological responses to varying gravitational environments. This article may be obtained online without charge.

Sathishkumar Y, Krishnaraj C, Rajagopal K, Sen D, Lee YS.

High throughput de novo RNA sequencing elucidates novel responses in Penicillium chrysogenum under microgravity.

Bioprocess Biosyst Eng. 2015 Nov 24. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26603994

Note: ISS results.

Otsuka K, Cornelissen G, Kubo Y, Hyashi M, Yamamoto N, Shibata K, Aiba T, Furukawa S, Ohshima H, Mukai C.

Intrinsic cardiovascular autonomic regulatory system of astronauts exposed long-term to microgravity in space: Observational study.

npj Microgravity. 2015 Nov 30;1:15018.

http://www.nature.com/articles/npjmgrav201518

Note: ISS results. This article may be obtained online without charge.

Ogneva IV.

[Early development under microgravity conditions].

Biofizika. 2015 Sep-Oct;60(5):1024-35. Russian.

http://www.ncbi.nlm.nih.gov/pubmed/26591615

Note: Specific space flights or simulation techniques are not mentioned in the English abstract.

Reid MB.

Redox interventions to increase exercise performance.

J Physiol. 2015 Nov 20. [Epub ahead of print] Review.

http://www.ncbi.nlm.nih.gov/pubmed/26584644

Thornton W.

Comments on body mass changes during long-duration spaceflight.

Aerosp Med Hum Perform. 2015 Dec;86(12):1070-1. Comment.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/00000012/art00013

Note: This is a Comment on the article: Zwart SR, Laumius RD, Coen GK, Morgan JLL, Charles JB, Smith SM. Body mass changes during long-duration spaceflight. Aviat Space Environ Med. 2014;85:897-904, which appeared in Current Awareness List #614, 5 Sep 2014.

Parmar P, Perry R, Martin J, Vickers S, Baptista R, Edwards R, McArtor J, Mitchell L, Caruso J.

Net energy costs from resistive exercise done on flywheel-based hardware.

Isokinet Exerc Sci. 2015;23(4):221-7.

http://content.iospress.com/articles/isokinetics-and-exercise-science/ies597

Loveman GAM, Seddon FM, Jurd KM, Thacker JC, Fisher AS.

First aid oxygen treatment for decompression illness in the goat after simulated submarine escape.

Aerosp Med Hum Perform. 2015 Dec;86(12):1020-7.

http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/00000012/art00004

Sarabon N, Rosker J.

Effects of fourteen-day bed rest on trunk stabilizing functions in aging adults.

Biomed Res Int. 2015;2015:309386. Epub 2015 Oct 25.

http://www.ncbi.nlm.nih.gov/pubmed/26601104

Note: Bed rest study. This article may be obtained online without charge.

Salanova M, Gambara G, Moriggi M, Vasso M, Ungethuem U, Belavý DL, Felsenberg D, Cerretelli P, Gelfi C, Blottner D.

Vibration mechanosignals superimposed to resistive exercise result in baseline skeletal muscle transcriptome profiles following chronic disuse in bed rest.

Sci Rep. 2015 Nov 25;5:17027.

http://www.ncbi.nlm.nih.gov/pubmed/26596638

Note: Bed rest study. This article may be obtained online without charge.

Lomonosova YN, Turtikova OV, Shenkman BS.

Reduced expression of MyHC slow isoform in rat soleus during unloading is accompanied by alterations of endogenous inhibitors of calcineurin/NFAT signaling pathway.

J Muscle Res Cell Motil. 2015 Nov 20. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26589960

Note: Hindlimb unloading study.

Liu SZ, Jemiolo B, Lavin KM, Lester BE, Trappe SW, Trappe TA.

Prostaglandin E2/cyclooxygenase pathway in human skeletal muscle: Influence of muscle fiber type and age.

J Appl Physiol (1985). 2015 Nov 25:jap.00396.2015. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26607246

Zhao Y, Ma X, Wang J, Chen S, Yuan H, Xu A, Hang H, Wu L.

The Roles of p21 and Hus1 in generation and transmission of damage signals stimulated by low-dose alpha-particle irradiation.

Radiat Res. 2015 Nov 24. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26600172

Baulch JE, Geidzinski E, Tran KK, Yu L, Zhou YH, Limoli CL.