Status Report

NASA Spaceline Current Awareness List #673 13 November 2015

By SpaceRef Editor

November 13, 2015

Filed under ISS, Spaceline, Spaceline Current Awareness, US

Papers deriving from NASA support:

Wotring VE.

Chemical potency and degradation products of medications stored over 550 earth days at the International Space Station.

AAPS J. 2015 Nov 6. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26546565

PI: V.E. Wotring

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: 3.799

Funding: “The study was funded by the NASA Human Research Program.”

Eikema DJ, Chien JH, Stergiou N, Myers SA, Scott-Pandorf MM, Bloomberg JJ, Mukherjee M.

Optic flow improves adaptability of spatiotemporal characteristics during split-belt locomotor adaptation with tactile stimulation.

Exp Brain Res. 2015 Nov 2. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26525712

Journal Impact Factor: 2.036

Funding: “This study was supported by NASA Experimental Program to Stimulate Competitive Research (EPSCoR) grant number NNX11AM06A and the Center of Biomedical Research Excellence grant (1P20GM109090-01) from NIGMS/NIH.” J.J. Bloomberg is at NASA Johnson Space Center.

Lin CJ, Smibert P, Zhao X, Hu JF, Ramroop J, Kellner SM, Benton MA, Govind S, Dedon PC, Sternglanz R, Lai EC.

An extensive allelic series of Drosophila kae1 mutants reveals diverse and tissue-specific requirements for t6A biogenesis.

RNA. 2015 Oct 29. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26516084

PI: S. Govind

Journal Impact Factor: 4.936

Funding: “Work in the Govind laboratory was supported by NSF-1121817, NASA award NNX15AB42G, and a Howard and Vicki Palefsky Fellowship to J. R. Work in the Dedon laboratory was supported by the Singapore National Research Foundation under its Singapore-MIT Alliance for Research and Technology, the National Institute of Environmental Health Science (ES017010, ES022858, ES002109), the National Science Foundation (MCB-1412379), and a fellowship from the Deutsche Forschungsgemeinschaft (S.M.K.). Work in the Sternglanz laboratory was supported by P01-GM088297. Work in the Lai laboratory was supported by the Burroughs Wellcome Foundation, the National Institutes of Health (R01-GM083300), the National Institute of Neurological Disorders and Stroke (R01-NS083833), and Memorial Sloan-Kettering Core grant P30-CA008748.”

Harper JD, Cunitz BW, Dunmire B, Lee FC, Sorensen MD, Hsi RS, Thiel J, Wessells H, Lingeman JE, Bailey MR.

First-in-human clinical trial of ultrasonic propulsion of kidney stones.

J Urol. 2015 Oct 29. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26521719

PIs: H. Wessells, M.R. Bailey

Journal Impact Factor: 4.471

Funding: “This trial was supported by the NSBRI through NASA NCC 9-58. Research and development were supported by grants from the National Institute of Diabetes and Digestive and Kidney Diseases (DK043881 and DK092197) and from the NSBRI. Additional funding was provided by the UW Applied Physics Laboratory, UW Department of Urology, CoMotion at the UW, The Wallace H. Coulter Foundation, and the UW Institute of Translational Health Sciences.”

Kugelman T, Zuloaga DG, Weber S, Raber J.

Post-training gamma irradiation-enhanced contextual fear memory associated with reduced neuronal activation of the infralimbic cortex.

Behav Brain Res. 2015 Oct 29;298(Pt B):1-11. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26522840

PIs: J. Raber, G.A. Nelson/J. Raber/NSCOR

Journal Impact Factor: 3.028

Funding: “This work was supported by NIDA T32 DA007262, NASA NNJ12ZSA001N and NSCOR NNX10AD59G, The Murdock Trust, and the development account of Dr. Raber.”

Muralidharan S, Sasi SP, Zuriaga MA, Hirschi KK, Porada CD, Coleman MA, Walsh KX, Yan X, Goukassian DA.

Ionizing particle radiation as a modulator of endogenous bone marrow cell reprogramming: Implications for hematological cancers.

Front Oncol. 2015 Oct 14;5:231. Review.

http://www.ncbi.nlm.nih.gov/pubmed/26528440

PIs: D.A. Goukassian, C.D. Porada

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “This work was supported by the National Aeronautics and Space Administration (NASA) under Grant No. NNX11AD22G and American Heart Association (AHA) under Grant No. 14GRNT18860032 to DAG and NASA Grant No. NNX13AB67G to CDP.”

George KA, Hada M, Cucinotta FA.

Biological effectiveness of accelerated protons for chromosome exchanges.

Front Oncol. 2015 Oct 19;5:226.

http://www.ncbi.nlm.nih.gov/pubmed/26539409

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “Financial support for this work was provided by National Aeronautics and Space Administration’s Space Radiation Program Element (NASA contract number NAS9-02078).”

Roy R, Bassham DC.

Gravitropism and lateral root emergence are dependent on the trans-Golgi network protein TNO1.

Front Plant Sci. 2015 Nov 12;6.

http://journal.frontiersin.org/article/10.3389/fpls.2015.00969/abstract

PI: D.C. Bassham

Journal Impact Factor: 3.948

Funding: “This work was supported by a grant from the National Aeronautics and Space Administration (grant no. NNX09AK78G) to DB.”

______________________________________________________

Other papers of interest:

Brandt A, Posthoff E, de Vera JP, Onofri S, Ott S.

Characterisation of growth and ultrastructural effects of the Xanthoria elegans photobiont after 1.5 years of space exposure on the International Space Station.

Orig Life Evol Biosph. 2015 Nov 2. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26526425

Note: ISS results.

Ivanov AS, Medvedev AE, Buneeva OA, Gnedenko OV, Ershov PV, Mezencev YV, Yablokov EO, Kaluzhsky LA, Florinskaya AV, Moskaleva NE, Zgoda VG.

[Influence of gravity discharge on the content of isatin-binding proteins in mice: Results of ground-based and space research under the program Bion-M N^o 1].

Biomed Khim. 2015 Sep;61(5):632-5. Russian.

http://www.ncbi.nlm.nih.gov/pubmed/26539872

Note: Bion-M1 results.

Janak JC, Howard JT, Goei KA, Weber R, Muniz GW, Hinojosa-Laborde C, Convertino VA.

Predictors of the onset of hemodynamic decompensation during progressive central hypovolemia: Comparison of the peripheral perfusion index, pulse pressure variability, and compensatory reserve index.

Shock. 2015 Oct 29. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26529655

Wang Y, Javed I, Liu Y, Lu S, Peng G, Zhang Y, Qing H, Deng Y.

Effect of prolonged simulated microgravity on metabolic proteins in rat hippocampus: Steps toward safe space travel.

J Proteome Res. 2015 Nov 2. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26523826

Note: Hindlimb unloading study.

Berardinelli F, De Vitis M, Nieri D, Cherubini R, De Nadal V, Gerardi S, Tanzarella C, Sgura A, Antoccia A.

mBAND and mFISH analysis of chromosomal aberrations and breakpoint distribution in chromosome 1 of AG01522 human fibroblasts that were exposed to radiation of different qualities.

Mutat Res Genet Toxicol Environ Mutagen. 2015 Nov;793:55-63. Epub 2015 May 30.

http://www.ncbi.nlm.nih.gov/pubmed/26520373

Yang W, Zhang H.

Effects of hindlimb unloading on neurotrophins in the rat spinal cord and soleus muscle.

Brain Res. 2015 Oct 31. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26529644

Note: Hindlimb unloading study.

Chazaud B.

Inflammation during skeletal muscle regeneration and tissue remodeling-application to exercise-induced muscle damage management.

Immunol Cell Biol. 2015 Nov 3. [Epub ahead of print] Review.

http://www.ncbi.nlm.nih.gov/pubmed/26526620

Jang J, Yun HY, Park J, Lim K.

Protective effect of branched chain amino acids on hindlimb suspension-induced muscle atrophy in growing rats.

J Exerc Nutrition Biochem. 2015 Sep;19(3):183-9. Epub 2015 Jul 31.

http://www.ncbi.nlm.nih.gov/pubmed/26527098

Note: Hindlimb unloading study. This article may be obtained online without charge.

Li Y, Zhong G, Sun W, Zhao C, Zhang P, Song J, Zhao D, Jin X, Li Q, Ling S, Li Y.

CD44 deficiency inhibits unloading-induced cortical bone loss through downregulation of osteoclast activity.

Sci Rep. 2015 Nov 4;5:16124.

http://www.ncbi.nlm.nih.gov/pubmed/26530337

Note: Hindlimb unloading study. This article may be obtained online without charge.

Ko CH, Siu WS, Chan CL, Koon CM, Fung KP, Li YZ, Li YH, Leung PC.

Bone protection effects of a novel Chinese herbal formula, Taikong Yangxin Prescription (TKYXP), in hindlimb unloaded rats against bone deterioration.

Chin J Integr Med. 2015 Oct;21(10):759-64. Epub 2015 Nov 3.

http://www.ncbi.nlm.nih.gov/pubmed/26525547

Note: Hindlimb unloading study.

Beaton-Green LA, Lachapelle S, Straube U, Wilkins RC.

Evolution of the Health Canada astronaut biodosimetry program with a view toward international harmonization.

Mutat Res Genet Toxicol Environ Mutagen. 2015 Nov;793:101-6. Epub 2015 Jul 29.

http://www.ncbi.nlm.nih.gov/pubmed/26520379

Vimal VP, Lackner JR, DiZio P.

Learning dynamic control of body roll orientation.

Exp Brain Res. 2015 Nov 2. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26525709

Spaeth AM, Dinges DF, Goel N.

Resting metabolic rate varies by race and by sleep duration.

Obesity. 2015 Nov 5. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26538305

Kimura Y, Kimura S, Sato S, Katoh H, Abe T, Arai M, Tomita-Yokotani K.

Evaluation of a cyanobacterium, Nostoc sp. HK-01, as food material for space agriculture on Mars.

Biol Sci Space. 2015;29:24-31.

https://www.jstage.jst.go.jp/article/bss/29/0/29_24/_article

Hytönen VP, Wehrle-Haller B.

Mechanosensing in cell-matrix adhesions – Converting tension into chemical signals.

Exp Cell Res. 2015 Oct 27. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26518118

Dupont S.

Role of YAP/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction.

Exp Cell Res. 2015 Oct 30. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26524510

Doyle AD, Yamada KM.

Mechanosensing via cell-matrix adhesions in 3D microenvironments.

Exp Cell Res. 2015 Oct 30. [Epub ahead of print] Review.

http://www.ncbi.nlm.nih.gov/pubmed/26524505

Note: This article may be obtained online without charge.

Komorowski M, Fleming S.

Intubation after rapid sequence induction performed by non-medical personnel during space exploration missions: A simulation pilot study in a Mars analogue environment.

Extrem Physiol Med. 2015 Nov 1;4:19.

http://www.ncbi.nlm.nih.gov/pubmed/26527252

Note: The simulation was conducted in the Mars Desert Research Station in Utah. This article may be obtained online without charge.