NASA Spaceline Current Awareness List #661 21 August 2015

Please note: Research Highlights of selected Space Life and Physical Sciences research are now available for download (in PDF) on the Task Book website at Space Life and Physical Sciences Research Highlights.

Papers deriving from NASA support:

1
Broxterman RM, Craig JC, Ade CJ, Wilcox SL, Barstow TJ.
The effect of resting blood flow occlusion on exercise tolerance and W’.
Am J Physiol Regul Integr Comp Physiol. 2015 Jul 29:ajpregu.00283.2015. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26224689
PI: T.J. Barstow
Journal Impact Factor: 3.106
Funding: “This work was supported by the National Aeronautics and Space Administration (NASA) under Grant NNX10AK60G awarded to TJB and by NASA Experimental Program to Stimulate Competitive Research (EPSCoR) under Grant NNX11AM05A supporting RMB.”

2
Lerchl K, Rakova N, Dahlmann A, Rauh M, Goller U, Basner M, Dinges DF, Beck L, Agureev A, Larina I, Baranov V, Morukov B, Eckardt KU, Vassilieva G, Wabel P, Vienken J, Kirsch K, Johannes B, Krannich A, Luft FC, Titze J.
Agreement between 24-hour salt ingestion and sodium excretion in a controlled environment.
Hypertension. 2015 Aug 10. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26259596
PIs: M. Basner, D. Dinges
Note: Data are from the Mars500 Project.
Journal Impact Factor: 6.48
Funding: “Grants from the German Federal Ministry for Economics and Technology/DLR Forschung unter Weltraumbedingungen (50WB0920), the Interdisciplinary Centre for Clinical Research (IZKF Junior Research Group 2), the National Institutes of Health (NIH, RO1 HL118579-01), the AHA (14SFRN20770008), and the Vanderbilt Clinical and Translational Science Award grant UL1 TR000445 from National Center for Advancing Translational Science/NIH supported J. Titze. M. Basner and D.F. Dinges were supported by the National Space Biomedical Research Institute through National Aeronautics and Space Administration cooperative agreement NCC 9-58 and by the Institute for Experimental Psychiatry Research Foundation.”

3
Weerts AP, Pattyn N, Putcha L, Hoag SW, Van Ombergen A, Hallgren E, Van de Heyning PH, Wuyts FL.
Restricted sedation and absence of cognitive impairments after administration of intranasal scopolamine.
J Psychopharmacol. 2015 Aug 12. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26268532
Journal Impact Factor: 3.593
Funding: “This research was made possible by the Belgian Science Policy program PRODEX-9 project SPIN-D in support of the European Space Agency AO-2004-093 corresponding project. Angelique Van Ombergen is a research fellow for the Research Foundation Flanders (FWO Vlaanderen; grant 11N6414N).” L. Putcha is at NASA Johnson Space Center.

4
Lee FC, Hsi RS, Sorensen MD, Dunmire B, Liu Z, Bailey MR, Harper JD.
Renal vasoconstriction occurs early during clinical SWL using a renal protection protocol.
J Endourol. 2015 Aug 3. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26239232
PI: M.R. Bailey
Journal Impact Factor: 1.708
Funding: “Funding was provided through the NIH DK43881 and DK092197, and the National Space Biomedical Research Institute through NASA NCC 9-58.”

5
Wallace IJ, Pagnotti GM, Rubin-Sigler J, Naeher M, Copes LE, Judex S, Rubin CT, Demes B.
Focal enhancement of the skeleton to exercise correlates to mesenchymal stem cell responsivity rather than peak external forces.
J Exp Biol. 2015 Jul 31. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26232415
PI: S. Judex
Journal Impact Factor: 2.897
Funding: “Supported primarily by a grant from the L.S.B. Leakey Foundation (49357), as well as grants from the National Science Foundation (BCS 0935321), the National Aeronautics and Space Administration (NNX12AL25G and NNX08BA35G), the National Institutes of Health (AR 043498), and Sigma Xi (G20120315159591).”

6
Pecaut MJ, Mehrotra S, Luo-Owen X, Bayeta EJ, Bellinger DL, Gridley DS.
Chlorisondamine, a sympathetic ganglionic blocker, moderates the effects of whole-body irradiation (WBI) on early host defense to a live bacterial challenge.
Immunol Lett. 2015 Jul 30. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26235133
Journal Impact Factor: 2.512
Funding: “Funding for this work was provided by a NASA Cooperative Agreement (NNX08AP21G) and the LLU Department of Radiation Medicine.”

7
Sundaresan A, Marriott K, Mao J, Bhuiyan S, Denkins P.
The effects of benzofuran-2-carboxylic acid derivatives as countermeasures in immune modulation and cancer cell inhibition.
Microgravity Sci Technol. 2015 Jun 1;27(3):129-40.
http://link.springer.com/article/10.1007/s12217-014-9408-7#
Note: A rotating-wall vessel culture system was used.
Journal Impact Factor: 0.910
Funding: No funding cited. P. Denkins is at NASA Johnson Space Center.

8
Bacher JW, Sievers CK, Albrecht DM, Grimes IC, Weiss JM, Matkowskyj KA, Agni RM, Vyazunova I, Clipson L, Storts DR, Thliveris AT, Halberg RB.
Improved detection of microsatellite instability in early colorectal lesions.
PLoS One. 2015 Aug 7;10(8):e0132727.
http://www.ncbi.nlm.nih.gov/pubmed/26252492
PI: J.W. Bacher
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.234
Funding: “Support was provided to JWB and RBH from the Promega Corporation and to RBH from the School of Public Health and Medicine, the Department of Medicine, Division of Gastroenterology and Hepatology, as well as Carbone Cancer Center (P30 CA014520) at University of Wisconsin. JMW was supported by a Mentored Research Scholar Grant in Applied and Clinical Research, MRSG-13-144-01-CPHPS from the American Cancer Society and by the University of Wisconsin Institute for Clinical and Translational Research through the National Center for Advancing Translational Sciences (NCATS), grant UL1TR000427. . . Funding for the initial development of the LMRs was provided by NASA grants NAG9-1525 and NNX07AQ02G to JWB.”

9
Li Z, Doho G, Zheng X, Jella KK, Li S, Wang Y, Dynan WS.
Co-culturing with high-charge and energy particle irradiated cells increases mutagenic joining of enzymatically induced DNA double-strand breaks in nonirradiated cells.
Radiat Res. 2015 Aug 18. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26284422
PIs: W. Dynan; Y. Wang/W. Dynan/NSCOR
Journal Impact Factor: 2.991
Funding: “Financial support was provided by NASA award no. NNX15AD63G and NASA Specialized Center of Research award no. NNX11AC30G.”

10
Rabin BM, Carrihill-Knoll KL, Shukitt-Hale B.
Comparison of the effectiveness of exposure to low-LET helium particles (He) and gamma rays (Cs) on the disruption of cognitive performance.
Radiat Res. 2015 Aug 18. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26284421
PI: B.M. Rabin
Journal Impact Factor: 2.911
Funding: “This research was supported by NASA grants NNX08AM66G and NNX13AB73G.”

11
Wage J, Ma L, Peluso M, Lamont C, Evens AM, Hahnfeldt P, Hlatky L, Beheshti A.
Proton irradiation impacts age-driven modulations of cancer progression influenced by immune system transcriptome modifications from splenic tissue.
J Radiat Res. 2015 Aug 7. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26253138
PIs: L. Hlatky; L. Hlatky/P. Hahnfeldt/NSCOR
Note: This article may be obtained online without charge.
Journal Impact Factor: 1.797
Funding: “Funding for this work was supported by the National Aeronautics and Space Administration under NSCOR Grant Nos NNJ06HA28G and NNX11AK26G issued through the Human Research Program to LH and by Award Number U54CA149233 from the National Cancer Institute, to LH.”

12
Heilbronn L.
Neutron properties and definitions.
THREE. 2015 Jul 9.
http://three.jsc.nasa.gov/articles/Heilbronn_Neutron_Supplement.pdf
Note: This article may be obtained online without charge.
Journal Impact Factor: Not applicable
Funding: No funding cited.

13
Morales JC, Motea EA, Patidar PL, Fattah FJ, Ilcheva M, Burma S, Story MD, Boothman DA.
RNA transcription termination factors and persistent R-loops: Potential carcinogenic determinants after high or low LET IR.
THREE. 2015 Jul 9.
http://three.jsc.nasa.gov/articles/Boothman_R-Loop_Factors.pdf
Note: This article may be obtained online without charge.
Journal Impact Factor: Not applicable
Funding: No funding cited.

14
Johannes B, Sitev AS, Vinokhodova AG, Salnitski VP, Savchenko EG, Artyukhova AE, Bubeev YA, Morukov BV, Tafforin C, Basner M, Dinges DF, Rittweger J.
Wireless monitoring of changes in crew relations during long-duration mission simulation.
PLoS One. 2015 Aug 7;10(8):e0134814.
http://www.ncbi.nlm.nih.gov/pubmed/26252656
PIs: M. Basner, D. Dinges
Note: Data are from the Mars500 Project. This article may be obtained online without charge.
Journal Impact Factor: 3.234
Funding: “The actigraphy data were collected in a study supported by the National Space Biomedical Research Institute (NSBRI) through NASA NCC 9–58 and by the Institute for Experimental Psychiatry Research Foundation.”

15
Alliger GM, Cerasoli CP, Tannenbaum SI, Vessey WB.
Team resilience: How teams flourish under pressure.
Organ Dyn. 2015 Jun 13. [Article in Press]
http://www.sciencedirect.com/science/article/pii/S009026161500039X
PI: S.I. Tannenbaum
Journal Impact Factor: 0.789
Funding: “This work was supported, in part, by Grant NNX11AR22G from the National Aeronautics and Space Administration (NASA).”

16
Hursh SR, Roma PG.
Behavioral economics and the analysis of consumption and choice.
Manag Decis Econ. 2015 May. [Article in Press]
http://onlinelibrary.wiley.com/doi/10.1002/mde.2724/abstract;jsessionid=02530405949D55522272D3F0BFD2FB07.f02t03
PI: P.G. Roma
Journal Impact Factor: Not available for this publication
Funding: “Manuscript preparation was supported by intramural funds from the Institutes for Behavior Resources as well as funding from US National Aeronautics and Space Administration (NASA) grant NNX13AB39G (P. G. R.) and US National Space Biomedical Research Institute (NSBRI) Directed Research project NBPF00008 (P. G. R.) through NASA cooperative agreement NCC 9-58-NBPF01602.”

17
Roma PG, Hursh SR, Hudja S.
Hypothetical purchase task questionnaires for behavioral economic assessments of value and motivation.
Manag Decis Econ. 2015 May 18. [Article in Press]
http://onlinelibrary.wiley.com/doi/10.1002/mde.2718/abstract
PI: P.G. Roma
Journal Impact Factor: Not available for this journal
Funding: “This work was supported by intramural funds from the Institutes for Behavior Resources. Manuscript preparation was supported by intramural funds from the Institutes for Behavior Resources as well as funding from US National Aeronautics and Space Administration (NASA) grant NNX13AB39G (P. G. R.) and US National Space Biomedical Research Institute (NSBRI) Directed Research project NBPF00008 (P. G. R.) through NASA cooperative agreement NCC 9-58-NBPF01602.”

18
Vijayan S, Klerman EB, Adler GK, Kopell N.
Thalamic mechanisms underlying alpha-delta sleep with implications for fibromyalgia.
J Neurophysiol. 2015 Aug 5:jn.00280.2015. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26245315
PI: E.B. Klerman
Journal Impact Factor: 2.887
Funding: “SV acknowledges support from National Science Foundation (NSF) Grant DMS-1042134. NJK acknowledges support from NSF Grants DMS-1042134 and DMS-1225647. GKA acknowledges support from National Institutes of Health (NIH) grant K24 HL103845. EBK is supported by NIH P01-AG009975, K24-HL105664, R01-HL-114088 and R01-GM-105018 plus NASA Cooperative Agreement NCC9-58 with the National Space and Biomedical Research Institute HFP02802. The original experiments were supported by NIH RO1-AR-43130, M01-RR- 0635, K01-AG-00661, R01-GM-53559, K02-MH-61637 NASA Cooperative Agreement NCC9-58 with the National Space and Biomedical Research Institute.”

19
Asrar FM, Asrar S, Clark JB, Kendall DJ, Ngo-Anh TJ, Brazeau S, Hulsroj P, Williams RS.
Help from above: outer space and the fight against Ebola.
Lancet Infect Dis. 2015 Aug;15(8):873-5. Epub 2015 Jul 19.
http://www.ncbi.nlm.nih.gov/pubmed/26227751
Journal Impact Factor: 22.433
Funding: No funding cited. R. S. Williams is at NASA Headquarters.
______________________________________________________

Other papers of interest:

1
Bourrelly A, McIntyre J, Luyat M.
Perception of affordances during long-term exposure to weightlessness in the International Space Station.
Cogn Process. 2015 Jul 31. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26224263
Note: ISS results.

2
Taylor PW.
Impact of space flight on bacterial virulence and antibiotic susceptibility.
Infect Drug Resist. 2015 Jul 30;8:249-62. Review.
http://www.ncbi.nlm.nih.gov/pubmed/26251622
Note: STS, Mir, and ISS results are discussed. This article may be obtained online without charge.

3
Giard T, Crevecoeur F, McIntyre J, Thonnard JL, Lefèvre P.
Inertial torque during reaching directly impacts grip-force adaptation to weightless objects.
Exp Brain Res. 2015 Aug 12. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26265124
Note: Parabolic flight results.

4
Solonin Iu G, Markov AL, Bojko ER, Akanov AA, Yeshmanova AK.
[Comparison of the results of satellite studies of “Mars-500” experiment participants in Syktyvkar and Almaty].
Fiziol Cheloveka. 2015 May-Jun;41(3):98-105. Russian.
http://www.ncbi.nlm.nih.gov/pubmed/26237953
Note: Mars500 Project results.

5
Chen Y, Zhang C, Zhang M, Fu X.
Three statistical experimental designs for enhancing yield of active compounds from herbal medicines and anti-motion sickness bioactivity.
Pharmacogn Mag. 2015 Jul-Sep;11(43):435-43.
http://www.ncbi.nlm.nih.gov/pubmed/26246716
Note: This article may be obtained online without charge.

6
Wang Z, Bai Y, Yu J, Liu H, Cheng Y, Liu Y, Xie X, Ma J, Bao J.
Caveolae regulates vasoconstriction of conduit arteries to angiotensin II in hindlimb unweighted rats.
J Physiol. 2015 Aug 10. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26260249
Note: Hindlimb unloading study.

7
Su L, Guo Y, Wang Y, Wang D, Liu C.
No effect of artificial gravity on lung function with exercise training during head-down bed rest.
Int J Astrobiology. 2015:1-7. [Article in Press]
http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=9896049&fulltextType=RA&fileId=S1473550415000245
Note: Bed rest study.

8
Egawa T, Goto A, Ohno Y, Yokoyama S, Ikuta A, Suzuki M, Sugiura T, Ohira Y, Yoshioka T, Hayashi T, Goto K.
Involvement of AMPK in regulating slow-twitch muscle atrophy during hindlimb unloading in mice.
Am J Physiol Endocrinol Metab. 2015 Aug 4:ajpendo.00165.2015. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26244519
Note: Hindlimb unloading study.

9
Cheon W, Lim K.
Change of gene expression on protein uptake composition and hindlimb-suspension in rat skeletal muscle.
J Exerc Nutrition Biochem. 2015 Jun;19(2):107-13. Epub 2015 Jun 30.
http://www.ncbi.nlm.nih.gov/pubmed/26244129
Note: Hindlimb unloading study. This article may be obtained online without charge.

10
Lerebours C, Buenzli PR, Scheiner S, Pivonka P.
A multiscale mechanobiological model of bone remodelling predicts site-specific bone loss in the femur during osteoporosis and mechanical disuse.
Biomech Model Mechanobiol. 2015 Aug 4. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26239380

11
Macione J, Long D, Nesbitt S, Wentzell S, Yokota H, Pandit V, Kotha S.
Stimulation of osteoblast differentiation with guided ultrasound waves.
J Ther Ultrasound. 2015 Aug 5;3:12.
http://www.ncbi.nlm.nih.gov/pubmed/26246899
Note: This article may be obtained online without charge.

12
Zhao F, Vaughan TJ, McNamara LM.
Quantification of fluid shear stress in bone tissue engineering scaffolds with spherical and cubical pore architectures.
Biomech Model Mechanobiol. 2015 Jul 30. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26224148

13
Gnyubkin V, Guignandon A, Laroche N, Vanden-Bossche A, Normand M, Lafage-Proust MH, Vico L.
Effects of chronic hypergravity: From adaptive to deleterious responses in growing mouse skeleton.
J Appl Physiol (1985). 2015 Jul 30:jap.00364.2015. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26228999
Note: Centrifugation was used.

14
Florencio-Silva R, Sasso GR, Sasso-Cerri E, Simöes MJ, Cerri PS.
Biology of bone tissue: Structure, function, and factors that influence bone cells.
Biomed Res Int. 2015;2015:421746. Epub 2015 Jul 13.
http://www.ncbi.nlm.nih.gov/pubmed/26247020
Note: This article may be obtained online without charge.

15
Badilatti SD, Christen P, Levchuk A, Marangalou JH, van Rietbergen B, Parkinson I, Muller R.
Large-scale microstructural simulation of load-adaptive bone remodeling in whole human vertebrae.
Biomech Model Mechanobiol. 2015 Aug 9. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26255055

16
Castillo AB, Leucht P.
Bone homeostasis and repair: Forced into shape.
Curr Rheumatol Rep. 2015 Sep;17(9):537. Review.
http://www.ncbi.nlm.nih.gov/pubmed/26233599

17
Li K, Guo X, Jin Z, Ouyang X, Zeng Y, Feng J, Wang Y, Yao L, Ma L.
Effect of simulated microgravity on human brain gray matter and white matter – Evidence from MRI.
PLoS One. 2015 Aug 13;10(8):e0135835.
http://www.ncbi.nlm.nih.gov/pubmed/26270525
Note: Bed rest study. This article may be obtained online without charge.

18
Zhikrevetskaya S, Peregudova D, Danilov A, Plyusnina E, Krasnov G, Dmitriev A, Kudryavtseva A, Shaposhnikov M, Moskalev A.
Effect of low doses (5-40 cGy) of gamma-irradiation on lifespan and stress-related genes expression profile in Drosophila melanogaster.
PLoS One. 2015 Aug 6;10(8):e0133840.
http://www.ncbi.nlm.nih.gov/pubmed/26248317
Note: This article may be obtained online without charge.

19
Matsumoto Y, Hamada N, Aoki-Nakano M, Funayama T, Sakashita T, Wada S, Kakizaki T, Kobayashi Y, Furusawa Y.
Dependence of the bystander effect for micronucleus formation on dose of heavy-ion radiation in normal human fibroblasts.
Radiat Prot Dosimetry. 2015 Aug 4. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26242975

20
Santos-Júnior FF, de Freitas Pires A, Ribeiro NM, Mendonca VA, Alves JO, Soares PM, Ceccatto VM, Assreuy AM.
Sensorial, structural and functional response of rats subjected to hind limb immobilization.
Life Sci. 2015 Jul 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26231696
Note: Hindlimbs (pelvis, hip, knee, and ankle) were immobilized with waterproof tape.

21
Yau JM, DeAngelis GC, Angelaki DE.
Dissecting neural circuits for multisensory integration and crossmodal processing.
Philos Trans R Soc Lond B Biol Sci. 2015 Sep 19;370(1677).
http://www.ncbi.nlm.nih.gov/pubmed/26240418
Note: This article may be obtained online without charge.

22
Du X, Zhang Y, Tian Y, Huang W, Wu B, Zhang J.
The influence of spatial ability and experience on performance during spaceship rendezvous and docking.
Front Psychol. 2015 Jul 15;6:955.
http://www.ncbi.nlm.nih.gov/pubmed/26236252
Note: This article may be obtained online without charge.

23
Chan FM, Galatioto J, Amato M, Kim AH.
Normative data for rotational chair stratified by age.
Laryngoscope. 2015 Jul 30. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26227880

24
Yamamoto K, Shida S, Honda Y, Shono M, Miyake H, Oguri S, Sakamoto H, Momonoki YS.
Overexpression of acetylcholinesterase gene in rice results in enhancement of shoot gravitropism.
Biochem Biophys Res Commun. 2015 Aug 13. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26277389
Note: This article may be obtained online without charge.

25
Mai CD, Phung NT, To HT, Gonin M, Hoang GT, Nguyen KL, Do VN, Courtois B, Gantet P.
Genes controlling root development in rice.
Rice (N Y). 2014 Dec;7(1):30. Review. Epub 2014 Nov 28.
http://www.ncbi.nlm.nih.gov/pubmed/26224559
Note: This article may be obtained online without charge.

26
Kim JY, Ryu JY, Baek K, Park CM.
High temperature attenuates the gravitropism of inflorescence stems by inducing SHOOT GRAVITROPISM 5 alternative splicing in Arabidopsis.
New Phytol. 2015 Aug 10. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26256266

27
Gasparski AN, Beningo KA.
Mechanoreception at the cell membrane: More than the integrins.
Arch Biochem Biophys. 2015 Aug 1. [Epub ahead of print] Review.
http://www.ncbi.nlm.nih.gov/pubmed/26241498

28
Mohan K, Luo T, Robinson DN, Iglesias PA.
Cell shape regulation through mechanosensory feedback control.
J R Soc Interface. 2015 Aug 6;12(109).
http://www.ncbi.nlm.nih.gov/pubmed/26224568

29
Soattin L, Fiore M, Gavazzo P, Viti F, Facci P, Raiteri R, Difato F, Pusch M, Vassalli M.
The biophysics of piezo1 and piezo2 mechanosensitive channels.
Biophys Chem. 2015 Jul 11. [Epub ahead of print] Review.
http://www.ncbi.nlm.nih.gov/pubmed/26259784