NASA Spaceline Current Awareness List #660 7 August 2015

Please note: The next issue of SPACELINE Current Awareness (List #661) will be sent on August 21.

Papers deriving from NASA support:

1
Mednieks M, Khatri A, Hand AR.
Salivary gland protein expression after Bion-M1 and Space Shuttle STS-135 missions.
Gravit Space Res. 2015 Jul;3(1):2-19.
http://gravitationalandspacebiology.org/index.php/journal/article/view/678
PI: M. Mednieks
Note: STS-135 and Bion-M1 results. This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “Supported by NASA grant NNX09AP13G (MIM); CT Space Grant College Consortium (ARH); Roosa Family Foundation Memorial Fund of the Hartford Foundation for Public Giving; School of Dental Medicine (SDM) Alumni Research Funds; and the University of Connecticut Health Center (UCHC) High School Student Research Apprentice Program.”

2
Romer C, Forsman A.
The effects of the spaceflight environment on the vaginal mucin layer of the mouse.
Gravit Space Res. 2015 Jul;3(1):20-8.
http://gravitationalandspacebiology.org/index.php/journal/article/view/667
Note: STS-118 results. This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “The research performed in this article was funded by East Tennessee State University (ETSU) Department of Health Sciences; Amgen, Inc., Thousand Oaks, CA; BioServe Space Technologies, Boulder, CO; and NASA Cooperative Agreement (CA) NCC8-131.

3
Wise JTF, Xie H, Wise JP Jr, Mason M, Jeevarajan A, Wallace WT, Wise JP Sr.
Comparative toxicity of lunar, Martian dust simulants, and urban dust in human skin fibroblast cells.
Gravit Space Res. 2015 Jul;3(1):51-8.
http://gravitationalandspacebiology.org/index.php/journal/article/view/682
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “This work was supported by NASA grant # EP-08-01 (JPW), the Maine Center for Toxicology and Environmental Health, and the Department of Applied Medical Sciences, University of Southern Maine, Portland, ME.” A. Jeevarajan is at NASA Johnson Space Center.

4
Krishnan M, Janardhanan P, Roman L, Reddick RL, Natarajan M, van Haperen R, Habib SL, de Crom R, Mohan S.
Enhancing eNOS activity with simultaneous inhibition of IKKβ restores vascular function in Ins2 type-1 diabetic mice.
Lab Invest. 2015 Jul 27. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/p ubmed/26214584
PI: M. Natarajan
Journal Impact Factor: 3.676
Funding: “This study was supported by the NIH/NIDDK grant 5 RO1 DK096119 (SM), and the National Space Biomedical Research Institute (NSBRI) grant CA02802 through NASA NCC 9-58-298 (MN).”

5
Rojdev K, Atwell W.
Hydrogen- and methane-loaded shielding materials for mitigation of galactic cosmic rays and solar particle events.
Gravit Space Res. 2015 Jul;3(1):59-81.
http://gravitationalandspacebiology.org/index.php/journal/article/view/676
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: No funding cited. K. Rojdev is at NASA Johnson Space Center.

6
Rabin BM, Poulose SM, Carrihill-Knoll KL, Ramirez F, Bielinski DF, Heroux N, Shukitt-Hale B.
Acute effects of exposure to Fe and O particles on learning and memory.
Radiat Res. 2015 Jul 24. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26207687
PI: B.M. Rabin
Journal Impact Factor: 2.911
Funding: “This research was supported by NASA grant no. NNX13AB73G.”

7
Bellone JA, Rudobeck E, Hartman RE, Szücs A, Vlkolinský R.
A single low dose of proton radiation induces long-term behavioral and electrophysiological changes in mice.
Radiat Res. 2015 Jul 24. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26207690
PI: R. Vlkolinsky
Journal Impact Factor: 2.911
Funding: “This article is based on work supported by the National Aeronautics and Space Administration (NASA) under grant no. NNX11AE41G.”

8
Suresh Kumar MA, Peluso M, Chaudhary P, Dhawan J, Beheshti A, Manickam K, Thapar U, Pena L, Natarajan M, Hlatky L, Demple B, Naidu M.
Fractionated radiation exposure of rat spinal cords leads to latent neuro-inflammation in brain, cognitive deficits, and alterations in apurinic endonuclease 1.
PLoS One. 2015 Jul 24;10(7):e0133016.
http://www.ncbi.nlm.nih.gov/pubmed/26208353
PIs: L. Hlatky, M. Naidu
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.234
Funding: “NASA grants, NNX11AO89G and NNX13AD74G to MN; NASA grant NNX13AJ01G to LH.”

9
Mathieu JE, Tannenbaum SI, Kukenberger MR, Donsbach JS, Alliger GM.
Team role experience and orientation: A measure and tests of construct validity.
Group Organ Manage. 2015 Feb 1;40(1):6-34.
http://gom.sagepub.com/content/40/1/6.abstract
PI: S.I. Tannenbaum
Journal Impact Factor: 1.400
Funding: “The work was supported by Grant NNX11AR22G from the National Aeronautics and Space Administration (NASA) and Contract W91WAW-08-C-0021 from the Army Research Institute awarded to the authors.”

10
Seidler RD, Mulavara AP, Bloomberg JJ, Peters BT.
Individual predictors of sensorimotor adaptability.
Front Syst Neurosci. 2015 Jul 6;9:100. Review.
http://www.ncbi.nlm.nih.gov/pubmed/26217197
PIs: R.D. Seidler, A.P. Mulavara, J.J. Bloomberg
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “This work is supported by grants from the National Space Biomedical Research Institute (NASA NCC 9–58) and the National Aeronautics and Space Administration (NASA; NNX11AR02G).”

11
Goel N.
“Omics” approaches for sleep and circadian rhythm research: Biomarkers for identifying differential vulnerability to sleep loss.
Curr Sleep Med Rep. 2015 Mar;1(1):38-46. Review.
http://link.springer.com/article/10.1007%2Fs40675-014-0003-7
PI: N. Goel
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “Preparation of this manuscript was supported by ONR N00014-11-1-0361, NASA NNX14AN49G, and NIHMH102310.”

12
Goel N.
Parsing race by genetic ancestry.
Sleep. 2015 Jul 13. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26194571
PI: N. Goel
Journal Impact Factor: 4.591
Funding: “The preparation of this commentary was supported by ONR N00014-11-1-0361 and NASA NNX14AN49G.”

13
Abe T, Goel N, Basner M, Mollicone D, Rao H, Dinges DF.
Integration of sleep need and fatigue mitigation into human systems operation.
In: APA handbook of human systems integration. APA handbooks in psychology. Washington, DC: American Psychological Association, 2015. p. 177-91.
http://psycnet.apa.org/index.cfm?fa=search.displayRecord&uid=2014-29521-012
PI: N. Goel
Journal Impact Factor: Not applicable to this publication
Funding: No funding cited. PI reports funding under grant NNX14AN49G.

14
Heer M, Titze J, Smith SM, Baecker N.
Nutrition physiology and metabolism in spaceflight and analog studies.
Cham, Switzerland: Springer; 2015. 69 p.
http://www.springer.com/us/book/9783319185200
PI: S.M. Smith
Note: Chapters include: Nutritional Requirements in Space; Nutrition in Space; Energy, Macronutrient Supply, and Effects of Spaceflight; Fluid and Electrolyte Metabolism; Fat-Soluble Vitamins; Water-Soluble Vitamins; Minerals; and Supplements.
Funding: No funding cited. S.M. Smith is at NASA Johnson Space Center.

15
Graham T, Scorza R, Wheeler R, Smith B, Dardick C, Dixit A, Raines D, Callahan A, Srinivasan C, Spencer L, Richards J, Stutte G.
Over-expression of FT1 in plum (Prunus domestica) results in phenotypes compatible with spaceflight: A potential new candidate crop for bioregenerative life support systems.
Gravit Space Res. 2015 Jul;3(1):39-50.
http://gravitationalandspacebiology.org/index.php/journal/article/view/680
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “This work was supported by Oak Ridge Associated Universities’ (ORAU) NASA Post-Doctoral Research Fellowship Program (Thomas Graham); a NASA Center Innovation Fund grant through NASA Kennedy Space Center; the National Institutes of Health R21AT006580-01A1 (Brenda J. Smith); the Specialty Crops Research Initiative Competitive Grants Program, grant #0220036, from the USDA National Institute of Food and Agriculture; and a grant from the California Dried Plum Board.” R. Wheeler is at NASA Kennedy Space Center.
______________________________________________________

Other papers of interest:

1
Wang P, Wang Z, Wang D, Tian Y, Li F, Zhang S, Zhang L, Guo Y, Liu W, Wang C, Chen S, Guo J.
Altered gravity simulated by parabolic flight and water immersion leads to decreased trunk motion.
PLoS One. 2015 Jul 24;10(7):e0133398.
http://www.ncbi.nlm.nih.gov/pubmed/26208253
Note: Parabolic flight results. This article may be obtained online without charge.

2
Seo Y, Burns K, Fennell C, Kim JH, Gunstad J, Glickman E, McDaniel J.
The influence of exercise on cognitive performance in normobaric hypoxia.
High Alt Med Biol. 2015 Jul 27. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26214045

3
Crystal GJ, Salem MR.
Lower body negative pressure: Historical perspective, research findings, and clinical applications.
J Anesth Hist. 2015 Apr;1(2):49-54. Epub 2015 Feb 19.
http://www.ncbi.nlm.nih.gov/pubmed/26205572
Note: This article may be obtained online without charge.

4
Wang Y, Zou X, Guo Y, Wang L, Liu Y, Zeng Q, Zhang X.
Mechanical strain affects some microRNA profiles in pre-osteoblasts.
Cell Mol Biol Lett. 2015 Jul 24. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26208382
Note: Cells were stimulated with mechanical tensile strain of 2500 με at 0.5 Hz generated using a 4-point bending device.

5
Ashaolu JO, Enaibe BU, Ajao MS.
Prolonged head-down posture of bats induces remodeling of the aorta.
Gravit Space Res. 2015 Jul;3(1):29-38.
http://gravitationalandspacebiology.org/index.php/journal/article/view/668
Note: This article may be obtained online without charge.

6
Babcock LW, Knoblauch M, Clarke MS.
The role of myostatin and activin receptor IIB in the regulation of unloading induced myofiber type-specific skeletal muscle atrophy.
J Appl Physiol (1985). 2015 Jul 23:jap.00762.2014. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26205544
Note: Hindlimb unloading was used.

7
Ohira T, Okabe H, Kawano F, Fujita R, Ohira T, Ohira K, Oke Y, Nakai N, Roy RR, Edgerton VR, Ohira Y.
Speed and/or inclination-dependent mobilization of human leg muscles during walking with a unique exception.
Acta Astronaut. 2015 Nov-Dec;116:237-46.
http://www.sciencedirect.com/science/article/pii/S0094576515002878

8
Lindenroth L, Caplan N, Debuse D, Salomoni SE, Evetts S, Weber T.
A novel approach to activate deep spinal muscles in space—Results of a biomechanical model.
Acta Astronaut. 2015 Nov-Dec;116:202-10.
http://www.sciencedirect.com/science/article/pii/S0094576515002829
Note: From the Introduction: “. . . the aim of the present work was to evaluate the potential to use the FRED [Functional Re-adaptive Exercise Device] as a direct in-flight countermeasure to counteract atrophy of deep spinal muscles and to prevent the unloading-induced tonic-to-phasic shift of lumbo-pelvic muscle activation as it has been reported in a previous study after prolonged bed rest.”

9
Brooks NE, Myburgh KH, Storey KB.
Muscle satellite cells increase during hibernation in ground squirrels.
Comp Biochem Physiol B Biochem Mol Biol. 2015 Jul 26. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26219581

10
Scheiner S, Pivonka P, Hellmich C.
Poromicromechanics reveals that physiological bone strains induce osteocyte-stimulating lacunar pressure.
Biomech Model Mechanobiol. 2015 Jul 30. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26220453
Note: This article may be obtained online without charge.

11
Ramchandani D, Weber GF.
Interactions between osteopontin and vascular endothelial growth factor: Implications for skeletal disorders.
Bone. 2015 Jun 27;81:7-15. Review. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26123594

12
Lai X, Price C, Modla S, Thompson WR, Caplan J, Kirn-Safran CB, Wang L.
The dependences of osteocyte network on bone compartment, age, and disease.
Bone Res. 2015;3.
http://www.ncbi.nlm.nih.gov/pubmed/26213632
Note: This article may be obtained online without charge.

13
Pannkuk EL, Laiakis EC, Authier S, Wong K, Fornace AJ Jr.
Global metabolomic identification of long-term dose-dependent urinary biomarkers in nonhuman primates exposed to ionizing radiation.
Radiat Res. 2015 Jul 31. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26230079

14
Gluzman-Poltorak Z, Vainstein V, Basile LA.
Association of hematological nadirs and survival in a nonhuman primate model of hematopoietic syndrome of acute radiation syndrome.
Radiat Res. 2015 Jul 24. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26207689

15
Buonanno M, Randers-Person G, Smilenov LB, Kleiman NJ, Young E, Ponnayia B, Brenner DJ.
A mouse ear model for bystander studies induced by microbeam irradiation.
Radiat Res. 2015 Jul 24. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26207682

16
Morita H, Obata K, Abe C, Shiba D, Shirakawa M, Kudo T, Takahashi S.
Feasibility of a short-arm centrifuge for mouse hypergravity experiments.
PLoS One. 2015 Jul 29;10(7):e0133981.
http://www.ncbi.nlm.nih.gov/pubmed/26221724
Note: A short-arm centrifuge, developed for use in the Kibo module on the International Space Station, was used. This article may be obtained online without charge.

17
McGarvie LA, MacDougall HG, Halmagyi GM, Burgess AM, Weber KP, Curthoys IS.
The video Head Impulse Test (vHIT) of semicircular canal function – Age-dependent normative values of VOR gain in healthy subjects.
Front Neurol. 2015 Jul 8;6:154.
http://www.ncbi.nlm.nih.gov/pubmed/26217301
Note: This article may be obtained online without charge.

18
Meeßen J, Wuthenow P, Schille P, Rabbow E, de Vera JP, Ott S.
Resistance of the lichen Buellia frigida to simulated space conditions during the preflight tests for BIOMEX-Viability assay and morphological stability.
Astrobiology. 2015 Jul 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26218403
Note: Samples were exposed to vacuum, Mars-like atmosphere, irradiation, and temperature cycling to simulate conditions in space and on Mars.

19
Kolesnikov YS, Kretynin SV, Volotovsky ID, Kordyum EL, Ruelland E, Kravets VS.
Molecular mechanisms of gravity perception and signal transduction in plants.
Protoplasma. 2015 Jul 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26215561

20
Barlow PW.
Leaf movements and their relationship with the lunisolar gravitational force.
Ann Bot. 2015 Aug;116(2):149-87.
http://www.ncbi.nlm.nih.gov/pubmed/26205177
Note: This article may be obtained online without charge.

21
Liang X, Fu Y, Liu H.
Isolation and characterization of enzyme-producing bacteria of the silkworm larval gut in bioregenerative life support system.
Acta Astronaut. 2015 Nov-Dec;116:247-53.
http://www.sciencedirect.com/science/article/pii/S0094576515002805

22
Pan B, Holt JR.
The molecules that mediate sensory transduction in the mammalian inner ear.
Curr Opin Neurobiol. 2015 Jul 24;34:165-71. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26218316

23
Shen J, Scheffer DI, Kwan KY, Corey DP.
SHIELD: An integrative gene expression database for inner ear research.
Database (Oxford). 2015 Jul 24;2015.
http://www.ncbi.nlm.nih.gov/pubmed/26209310
Note: This article may be obtained online without charge.

24
MacLeish MM, Akinyede JO, White RJ, Goswami N, Thomson WA.
Global space workforce development: A model for partnership building and knowledge transfer to developing space-faring societies.
Acta Astronaut. 2015 Nov-Dec;116:106-16.
http://www.sciencedirect.com/science/article/pii/S0094576515002738

25
Carrillo Esper R.
[Space medicine: Origins and current status in Mexico].
Cir Cir. 2015 May-Jun;83(3):181-2. Spanish.
http://www.ncbi.nlm.nih.gov/pubmed/26210614
Note: The editorial provides a brief history of aerospace medicine in Mexico with a tribute to Dr. Ramiro Iglesias. This article may be obtained online without charge.