NASA SPACELINE Current Awareness List #657 17 July 2015

Editor’s note: NASA’s various life sciences programs have prepared the SPACELINE Current Awareness updates since 1999 covering all aspects of space life science, gravitational biology, space medicine, and human factors. NASA does not maintain a website – nor does it have an archive of this resource online. However, SpaceRef does have a complete archive of SPACELINE updates all the way back to 1999 that can be accessed here: http://www.spaceref.com/news/mission.html?mid=188

Papers deriving from NASA support:

1
Chowdhury B, McGovern A, Cui Y, Choudhury SR, Cho IH, Cooper B, Chevassut T, Lossie AC, Irudayaraj J.
The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells.
Sci Rep. 2015 Apr 22;5:9281.
http://www.ncbi.nlm.nih.gov/pubmed/25901663
PI: J. Irudayaraj
Journal Impact Factor: 5.578
Funding: “Partial support for B.C. by the National Institute of Health (NIH), National Cancer Institute R25CA128770 Cancer Prevention Internship Program, support from the Indiana Clinical and Translational Sciences Institute funded, in part by Grant Number (TR000006) from the NIH, Showalter Trust Grant and the W.M. Keck Foundation.” PI reports funding under NNX12AN09G.

2
Sridharan DM, Chappell LJ, Whalen MK, Cucinotta FA, Pluth JM.
Defining the biological effectiveness of components of high-LET track structure.
Radiat Res. 2015 Jul;184(1):105-19. Epub 2015 Jun 26.
http://www.ncbi.nlm.nih.gov/pubmed/26114329
PI: J.M. Pluth
Journal Impact Factor: 2.911
Funding: “This project was supported by NASA award NNA06CD66I to JMP.”

3
O’Neill PM, Golge S, Slaba TC.
Badhwar-O’Neill 2014 galactic cosmic ray flux model description.
Houston, TX: NASA Johnson Space Center, 2015 Mar. 32 p. NASA/TP-2015-218569.
http://ston.jsc.nasa.gov/collections/TRS/listfiles.cgi?DOC=TP-2015-218569
PI: J.W. Norbury
Note: This article may be obtained online without charge.
Journal Impact Factor: Not applicable to this publication
Funding: “This work was partially funded by NASA under the Bioastronautics Contract (BC) number NAS902078.” The work also was supported by NASA’s Human Research Program, Radiation Health element as directed research.

4
Kroupa M, Bahadori A, Campbell-Ricketts T, Empl A, Hoang SM, Idarraga-Munoz J, Rios R, Semones E, Stoffle N, Tlustos L, Turecek D, Pinsky L.
A semiconductor radiation imaging pixel detector for space radiation dosimetry.
Life Sci Space Res. 2015 Jul 3. [Article in Press]
http://www.sciencedirect.com/science/article/pii/S2214552415000620
Journal Impact Factor: 1.183
Funding: “Financial support for much of the research described came from NASA’s Advanced Exploration Systems Program and the NASA Bioastronautics contract NAS9-02078, as well as from the University of Houston and from NASA via Wyle Science Technology and Engineering Group Contract Number: T72203.”

5
Townsend LW, Adamczyk AM, Werneth CM, Moussa HM, Townsend JP.
Estimates of extreme solar particle event radiation exposures on Mars.
Prog Nucl Sci Technol. 2014;4:793-7.
http://www.aesj.or.jp/publication/pnst004/data/793_797.pdf
PI: J.W. Norbury
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: No funding cited. This was supported by NASA’s Human Research Program, Radiation Health element as directed research.

6
Werneth CM, Maung KM, Ford WP, Norbury JW, Vera MD.
Elastic differential cross sections for space radiation applications.
Phys Rev C. 2014 Dec 9;90(6):064905.
http://journals.aps.org/prc/abstract/10.1103/PhysRevC.90.064905
PI: J.W. Norbury
Journal Impact Factor: 3.733
Funding: “This work was supported by the Human Research Program under the Human Exploration and Operations Mission Directorate of NASA and NASA Grant No. NNX13AH31AS05.”

7
Ruberti C, Kim SJ, Stefano G, Brandizzi F.
Unfolded protein response in plants: One master, many questions.
Curr Opin Plant Biol. 2015 Oct;27:59-66. Review. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26149756
PI: F. Brandizzi
Journal Impact Factor: 7.848
Funding: “This work was primarily supported by National Institutes of Health (GM101038) with contributing support from the Chemical Sciences, Geosciences and Biosciences Division, Office of Basic Energy Sciences, Office of Science, U.S. Department of Energy (DE-FG02-91ER20021), National Aeronautics and Science Administration (NNX12AN71G), National Science Foundation (MCB 1243792) and DOE Great Lakes Bioenergy Research Center (DOE Office of Science BER DE-FC02-07ER64494).”

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Other papers of interest:

1
Clément G, Allaway HC, Demel M, Golemis A, Kindrat AN, Melinyshyn AN, Merali T, Thirsk R.
Long-duration spaceflight increases depth ambiguity of reversible perspective figures.
PLoS One. 2015 Jul 6;10(7):e0132317.
http://www.ncbi.nlm.nih.gov/pubmed/26146839
Note: ISS results. This article may be obtained online without charge.

2
Tavakolinejad A, Rabbani M, Janmaleki M.
Effects of hypergravity on adipose-derived stem cell morphology, mechanical property and proliferation.
Biochem Biophys Res Commun. 2015 Jul 3. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26150354
Note: Centrifugation was used.

3
Dyment NA, Breidenbach AP, Schwartz AG, Russell RP, Aschbacher-Smith L, Liu H, Hagiwara Y, Jiang R, Thomopoulos S, Butler DL, Rowe DW.
Gdf5 progenitors give rise to fibrocartilage cells that mineralize via hedgehog signaling to form the zonal enthesis.
Dev Biol. 2015 Jun 30. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26141957

4
Thom SR, Bennett M, Banham ND, Chin W, Blake DF, Rosen A, Pollock NW, Madden D, Barak OF, Marroni A, Balestra C, Germonpre P, Pieri M, Cialoni D, Le PJ, Logue C, Lambert D, Hardy KR, Sward D, Yang M, Bhopale VM, Dujic Z.
Association of microparticles and neutrophil activation with decompression sickness.
J Appl Physiol (1985). 2015 Jul 2:jap.00380.2015. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26139218

5
Rickards CA, Johnson BD, Harvey RE, Convertino VA, Joyner MJ, Barnes JN.
Cerebral blood velocity regulation during progressive blood loss compared to lower body negative pressure in humans.
J Appl Physiol (1985). 2015 Jul 2:jap.00127.2015. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26139213

6
Graham ZA, Gallagher PM, Cardozo CP.
Focal adhesion kinase and its role in skeletal muscle.
J Muscle Res Cell Motil. 2015 Jul 4. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26142360

7
Wong A, Loots GG, Yellowley CE, Dosé AC, Genetos DC.
Parathyroid hormone regulation of hypoxia-inducible factor signaling in osteoblastic cells.
Bone. 2015 Jul 4. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26151122

8
Tracy BL, Stevens DL, Goodhead DT, Hill MA.
Variation in RBE for survival of V79-4 cells as a function of alpha-particle (helium ion) energy.
Radiat Res. 2015 Jul;184(1):33-45. Epub 2015 Jun 29.
http://www.ncbi.nlm.nih.gov/pubmed/26121227

9
Limoli C.
Your brain on Mars.
Radiat Res. 2015 Jul;184(1):1-2. Epub 2015 Jun 11. Comment.
http://www.ncbi.nlm.nih.gov/pubmed/26066080

10
Galen SS, Pardo V, Wyatt D, Diamond A, Brodith V, Pavlov A.
Validity of an interactive functional reach test.
Games Health J. 2015 Aug;4(4):278-84. Epub 2015 Apr 20.
http://www.ncbi.nlm.nih.gov/pubmed/26182215
Note: The NASA Task Load Index was used.

11
Nelson M, Gray K, Allen JP.
Group dynamics challenges: Insights from Biosphere 2 experiments.
Life Sci Space Res. 2015 Jul 9. [Article in Press]
http://www.sciencedirect.com/science/article/pii/S2214552415000656

12
Chan AH, Hoffmann ER.
Effect of display location on control-display stereotype strength for translational and rotational controls with linear displays.
Ergonomics. 2015 Jul 6:1-20. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/26147193

13
Kozeko L, Talalaiev O, Neimash V, Povarchuk V.
A protective role of HSP90 chaperone in gamma-irradiated Arabidopsis thaliana seeds.
Life Sci Space Res. 2015 Jul 9. [Article in Press]
http://www.sciencedirect.com/science/article/pii/S2214552415000644

14
Paluch EK, Nelson CM, Biais N, Fabry B, Moeller J, Pruitt BL, Wollnik C, Kudryasheva G, Rehfeldt F, Federle W.
Mechanotransduction: Use the force(s).
BMC Biol. 2015 Jul 4;13:47.
http://www.ncbi.nlm.nih.gov/pubmed/26141078
Note: This article may be obtained online without charge.