Status Report

NASA Spaceline Current Awareness List #630 – 9 January 2015

By SpaceRef Editor

January 9, 2015

Filed under ISS, Spaceline Current Awareness, US

Papers deriving from NASA support:

Woodard D, Knox G, Wood S, DiBiase C.

Off-vertical axis rotational assessment of transdermal scopolamine for motion sickness prophylaxis.

Gravit Space Res. 2014 Dec;2(2):13-20.

http://gravitationalandspacebiology.org/index.php/journal/article/view/639

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal.

Funding: “This study was funded in part by the Aerospace Medicine and Environmental Health Branch, Kennedy Space Center, Florida, and the Florida Space Research Institute.”

Washburn SA, Blattnig SR, Singleterry RC, Westover SC.

Active magnetic radiation shielding system analysis and key technologies.

Life Sci Space Res. 2015 Jan 5. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552414000686

PI: J. Norbury

Journal Impact Factor: 1.183

Funding: No funding cited. S.R. Blattnig and R.C. Singleterry are at NASA Langley Research Center.

Sanzari JK, Steven Wan X, Muehlmatt A, Lin L, Kennedy AR.

Comparison of changes over time in leukocyte counts in Yucatan minipigs irradiated with simulated solar particle event-like radiation.

Life Sci Space Res. 2014 Dec 30. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552414000662

PI: A.R. Kennedy

Journal Impact Factor: 1.183

Funding: “This work was supported by the Center of Acute Radiation Research (CARR) grant from the National Space Biomedical Research Institute (NSBRI) through NASA NCC 9-58 and NIH Training Grant 2T32CA00967.”

Aghara SK, Sriprisan SI, Singleterry RC, Sato T.

Shielding evaluation for solar particle events using MCNPX, PHITS and OLTARIS codes.

Life Sci Space Res. 2015 Jan 5. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552414000674

PI: J. Norbury

Journal Impact Factor: 1.183

Funding: “This study is in part supported by NASA LaRC grant number: NNX084T294 and NASA STI grant: NNX09AV17A.” R.C. Singleterry is at NASA Langley Research Center.

El-Ashmawy M, Delgado O, Cardentey A, Wright WE, Shay JW.

CDDO-Me protects normal lung and breast epithelial cells but not cancer cells from radiation.

PLoS One. 2014 Dec 23;9(12):e115600.

http://www.ncbi.nlm.nih.gov/pubmed/25536195

PIs: J.W. Shay; J.D. Minna/A.J. Fornace/J.W. Shay/W.E. Wright/NSCOR

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.534

Funding: “This work was supported in part by the National Aeronautics and Space Administration (NNJ05HD36GD, NNX09AU95G, and NNX11AC1G); the National Cancer Institute (Lung SPORE P50CA70907) (JWS); Howard Hughes Medical Institute Gilliam Fellowship (ME). This work was performed in laboratories constructed with support from National Institutes of Health grant C06 RR30414 (JWS).”

Christofidou-Solomidou M, Pietrofesa RA, Arguiri E, Schweitzer KS, Berdyshev EV, McCarthy M, Corbitt A, Alwood JS, Yu Y, Globus RK, Solomides CC, Ullrich RL, Petrache I.

Space radiation associated lung injury in a murine model.

Am J Physiol Lung Cell Mol Physiol. 2014 Dec 19:ajplung.00260.2014. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25526737

PIs: M. Christofidou-Solomidou; R.K. Globus; R.L. Ullrich/NSCOR

Journal Impact Factor: 4.041

Funding: “Funded by: NIH-R01 CA133470 (MCS), NIH-RC1AI081251 (MCS), NASA-NNJ11ZSA002NA (MCS), NIH-RO1HL077328 (IP), and NASA NNX09AM08G (RLU) and DOE-NASA Interagency Award no. DE-SC0001507, supported by the Office of Science (BER), US Department of Energy (RKG). We thank Marjorie Albrecht and Mary Van Demark for technical assistance.”

Clark TK, Newman MC, Oman CM, Merfeld DM, Young LR.

Human perceptual overestimation of whole-body roll tilt in hyper-gravity.

J Neurophysiol. 2014 Dec 24:jn.00095.2014. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25540216

PIs: C.M. Oman; L.R. Young; T.K. Clark, NSBRI Postdoctoral Fellowship Program

Note: A long-radius centrifuge was used.

Journal Impact Factor: 3.041

Funding: “This work was supported by the National Space Biomedical Research Institute (NSBRI) through NASA NCC9-58 (TKC, CMO, LRY) and via NIDCD/NIH R01 DC04158 (DMM).”

Chang A, Aeschbach D, Duffy JF, Czeisler CA.

Evening use of light-emitting eReaders negatively affects sleep, circadian timing, and next-morning alertness.

Proc Natl Acad Sci U S A. 2014 Dec 22. pii: 201418490. [Epub ahead of print].

http://www.ncbi.nlm.nih.gov/pubmed/25535358

PI: C.A. Czeisler

Note: This article may be obtained online without charge.

Journal Impact Factor: 9.809

Funding: “This work was supported by NIH Grant R01HL077453. The inpatient studies were conducted in the Harvard CTSC, supported by NCRR Grant UL1 RR025758. A-M.C. was supported in part by NIH Grant K01HL115458. D.A. was supported in part by the German Aerospace Center. J.F.D. was supported in part by NIH Grant R01HL094654. C.A.C. was supported in part by NASA NNX10AF47G and the National Space Biomedical Research Institute through NASA NCC 9-58.”

Liston DB, Stone LS.

Oculometric assessment of dynamic visual processing.

J Vis. 2014 Dec 19;14(14). pii: 12.

http://www.ncbi.nlm.nih.gov/pubmed/25527150

PI: L.S. Stone

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.727

Funding: “The development of this methodology has been supported over the past 10 years by NASA’s Human Health and Performance Program (111-10-10), NASA’s Human Factors Engineering Program (131-20-30), the National Science Foundation’s Program in Perception, Action, and Cognition Program (NSF 0924841), the National Space Biomedical Research Institute (SA 2002), the U.S. Air Force School of Aerospace Medicine, a NASA Ames Research Center Director’s Innovation Fund Award, and the Office of Naval Research (SAA2-402925).”

Ferl RJ.

Suborbital vehicles to study transition adaptation to spaceflight – Why biologists should care about the new suborbital flight opportunities.

Gravit Space Res. 2014 Dec;2(2):58-65.

http://gravitationalandspacebiology.org/index.php/journal/article/view/658

PIs: R.J. Ferl, A-L. Paul

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal.

Funding: “Support for spaceflight and suborbital research was provided by NNX12AN69G, NNX12AK80G to Robert J. Ferl and Anna-Lisa Paul, and flights awarded by the NASA Flight Opportunities Program.”

Smith DJ, Thakrar PJ, Bharrat AE, Dokos AG, Kinney TL, James LM, Lane MA, Khodadad CL, Maguire F, Maloney PF, Dawkins NL.

A balloon-based payload for Exposing Microorganisms in the Stratosphere (E-MIST).

Gravit Space Res. 2014 Dec;2(2):70-80.

http://gravitationalandspacebiology.org/index.php/journal/article/view/661

Note: Balloon flight results. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal.

Funding: No funding cited. D.J. Smith is at NASA Kennedy Space Center.

Fajardo-Cavazos P, Narvel R, Nicholson WL.

Differing responses in growth and spontaneous mutation to antibiotic resistance in Bacillus subtilis and Staphylococcus epidermidis cells exposed to simulated microgravity.

Gravit Space Res. 2014 Dec;2(2):34-45.

http://gravitationalandspacebiology.org/index.php/journal/article/view/660

PI: W.L. Nicholson

Note: A Rotating Wall Vessel was used. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal.

Funding: “This work was supported by a grant from the NASA Research Opportunities in Space Biology program (NNX12AN70G) to W.L.N. and P.F.-C., and by an internship from the NASA Florida Space Grant Consortium (NNX10AM01H).”

Sng NJ, Callaham J, Ferl RJ, Paul A-L.

Arabidopsis thaliana for spaceflight applications – Preparing dormant biology for passive stowage and on-orbit activation.

Gravit Space Res. 2014 Dec;2(2):81-9.

http://gravitationalandspacebiology.org/index.php/journal/article/view/666

PIs: R.J. Ferl, A-L. Paul

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal.

Funding: “This research was supported by NASA grants NNX07AH27G and NNX12AN69G to A-L.P. and R.J.F.”

______________________________________________________________________

Other papers of interest:

Reidt U, Helwig A, Plobner L, Lugmayr V, Treutlein U, Kharin S, Smirnov Y, Novikova N, Lenic J, Fetter V, Hummel T.

Study of initial colonization by environmental microorganisms in the Russian segment of the International Space Station (ISS).

Gravit Space Res. 2014 Dec;2(2):46-57.

http://gravitationalandspacebiology.org/index.php/journal/article/view/648

Note: ISS results. This article may be obtained online without charge.

Egusquiza RJ, Runyon RB, Ringel J, Seber CWC, Leyva G, Correa J, Roland CD, Umar M, Xiao M, Bushoven JT, Goto JJ.

Calcium oxalate crystal yield in various gravity environments.

Gravit Space Res. 2014 Dec;2(2):3-12.

http://gravitationalandspacebiology.org/index.php/journal/article/view/637

Note: Parabolic flight results. This article may be obtained online without charge.

Zaar M, Fedyk CG, Pidcoke HF, Scherer MR, Ryan KL, Rickards CA, Hinojosa-Laborde C, Convertino VA, Cap AP.

Platelet activation after presyncope by lower body negative pressure in humans.

PLoS One. 2014 Dec 29;9(12):e116174.

http://www.ncbi.nlm.nih.gov/pubmed/25546432

Note: This article may be obtained online without charge.

Lang-Ouellette D, Richard TG, Morin PJ.

Mammalian hibernation and regulation of lipid metabolism: A focus on non-coding RNAs.

Biochemistry (Mosc). 2014 Nov;79(11):1161-71. Review.

http://www.ncbi.nlm.nih.gov/pubmed/25540001

Note: This article may be obtained online without charge.

Porter C, Reidy PT, Bhattarai N, Sidossis LS, Rasmussen BB.

Resistance exercise training alters mitochondrial function in human skeletal muscle.

Med Sci Sports Exerc. 2014 Dec 23. [Epub ahead of print] Review.

http://www.ncbi.nlm.nih.gov/pubmed/25539479

Ogneva IV, Gnyubkin V, Laroche N, Maximova MV, Larina IM, Vico L.

Structure of the cortical cytoskeleton in fibres of postural muscles and cardiomyocytes of mice after 30-day 2g-centrifugation.

J Appl Physiol (1985). 2014 Dec 24:jap.00812.2014. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25539936

Note: A 2g centrifuge was used.

Ohno Y, Sugiura T, Ohira Y, Yoshioka T, Goto K.

Loading-associated expression of TRIM72 and caveolin-3 in antigravitational soleus muscle in mice.

Physiol Rep. 2014 Dec 24;2(12). pii: e12259. Print 2014 Dec 1.

http://www.ncbi.nlm.nih.gov/pubmed/25539835

Note: Hindlimb unloading study. This article may be obtained online without charge.

Blottner D, Bosutti A, Degens H, Schiffl G, Gutsmann M, Buehlmeier J, Rittweger J, Ganse B, Heer M, Salanova M.

Whey protein plus bicarbonate supplement has little effects on structural atrophy and proteolysis marker immunopatterns in skeletal muscle disuse during 21 days of bed rest.

J Musculoskelet Neuronal Interact. 2014 Dec;14(4):432-44.

http://www.ncbi.nlm.nih.gov/pubmed/25524969

Note: Bed rest study. This article may be obtained online without charge.

Nagano K, Hori H.

Promotion of apoptosis and cytochrome c depletion by a low-temperature environment in hindlimb-unloading rats.

J Musculoskelet Neuronal Interact. 2014 Dec 14;14(4):464-72.

http://www.ncbi.nlm.nih.gov/pubmed/25524972

Note: Hindlimb unloading study. This article may be obtained online without charge.

Grubbe MC, Thomsen JS, Nyengaard JR, Duruox M, Brüel A.

Growth hormone mitigates loss of periosteal bone formation and muscle mass in disuse osteopenic rats.

J Musculoskelet Neuronal Interact. 2014 Dec;14(4):473-83.

http://www.ncbi.nlm.nih.gov/pubmed/25524973

Note: Right hindlimbs were paralyzed. This article may be obtained online without charge.

Sample SJ, Heaton CM, Behan M, Bleedorn JA, Racette MA, Hao Z, Muir P.

Role of calcitonin gene-related peptide in functional adaptation of the skeleton.

PLoS One. 2014 Dec 23;9(12):e113959.

http://www.ncbi.nlm.nih.gov/pubmed/25536054

Note: Mechanical loading study using axial compression. This article may be obtained online without charge.

Lambers FM, Kuhn G, Weigt C, Koch KM, Schulte FA, Müller R.

Bone adaptation to cyclic loading in murine caudal vertebrae is maintained with age and directly correlated to the local micromechanical environment.

J Biomech. 2014 Dec 8. pii: S0021-9290(14)00608-3 [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25543278

Cucinotta FA.

Review of NASA approach to space radiation risk assessments for Mars exploration.

Health Phys. 2015 Feb;108(2):131-42.

http://www.ncbi.nlm.nih.gov/pubmed/25551493

Simon SL, Braby LA, Chang PY, Goodhead DT, Hora S, Kocher DC, Mabuchi K, Puskin JS, Richardson D, Rosenstein M, Tucker J, Vano E.

Biological effectiveness of photons and electrons as a function of energy.

Health Phys. 2015;108(2):143-4.

http://www.ncbi.nlm.nih.gov/pubmed/25551494

Chishti AA, Hellweg CE, Berger T, Baumstark-Khan C, Feles S, Kätzel T, Reitz G.

Life sciences in space research: Constitutive expression of tdTomato protein as a cytotoxicity and proliferation marker for space radiation biology.

Life Sci Space Res. 2015 Jan 6. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552414000698

Satterfield BC, Wisor JP, Field SA, Schmidt MA, Van Dongen HP.

TNFalpha G308A polymorphism is associated with resilience to sleep deprivation-induced psychomotor vigilance performance impairment in healthy young adults.

Brain Behav Immun. 2014 Dec 24. pii: S0889-1591(14)00572-8. [Epub ahead of print.]

http://www.ncbi.nlm.nih.gov/pubmed/25542735

Zhang S, Liu P, Chen L, Wang Y, Wang Z, Zhang B.

The effects of spheroid formation of adipose-derived stem cells in a microgravity bioreactor on stemness properties and therapeutic potential.

http://www.ncbi.nlm.nih.gov/pubmed/25522961

Note: The specific type of microgravity bioreactor is not specified.

Hayes MW, Stutte GW, McKeon-Bennett M, Murray PG.

Mutualism within a simulated microgravity environment – Piriformospora indica promotes the growth of Medicago truncatula.

Gravit Space Res. 2014 Dec;2(2):21-33.

http://gravitationalandspacebiology.org/index.php/journal/article/view/645

Note: A 2-D clinostat was used. This article may be obtained online without charge.

Sato EM, Hijazi H, Bennett MJ, Vissenberg K, Swarup R.