NASA Spaceline Current Awareness List #629 – 2 January 2015
Papers deriving from NASA support:
1
Ferl RJ, Koh J, Denison F, Paul AL.
Spaceflight induces specific alterations in the proteomes of Arabidopsis.
http://www.ncbi.nlm.nih.gov/pubmed/25517942
(PIs: R.J. Ferl, A-L. Paul)
Note: ISS results. This article may be obtained online without charge.
Journal Impact Factor: 2.512
Funding: “This research was supported by NASA grants NNX07AH270 and NNX09AL96G to R.J.F. and A.-L.P.”
2
Note: Beginning with the January 2015 issue, Aviation, Space, and Environmental Medicine (Aviat Space Environ Med), the journal of the Aerospace Medical Association, has been renamed Aerospace Medicine and Human Performance (Aerosp Med Human Perform). For more information, see the publisher’s website: http://www.asma.org/journal/amhp-journal.
Macias BR, Liu JHK, Grande-Gutierrez N, Hargens AR.
Intraocular and intracranial pressures during head-down tilt with lower body negative pressure.
Aerosp Med Human Perform. 2015 Jan;86(1):3-7.
http://www.ingentaconnect.com/content/asma/asem/2015/00000086/00000001/art00004
(PIs: A.R. Hargens; B.R. Macias, NSBRI Postdoctoral Fellowship Program)
Note: Study was conducted on astronauts who had completed a 6-month ISS mission.
Journal Impact Factor: 0.782
Funding: “This work was supported by the National Space Biomedical Research Institute through NCC 9-58 (to BRM). This study was funded by NASA grant #NNX13AJ12G (to ARH).”
3
Avin KG, Bloomfield SA, Gross TS, Warden SJ.
Biomechanical aspects of the muscle-bone interaction.
Curr Osteoporos Rep. 2014 Dec 17. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25515697
(PI: S.A. Bloomfield)
Journal Impact Factor: Not available for this journal.
Funding: “This contribution was made possible by support from the NASA Space Biology Research Programs (NNX13AL25G to S.A.B..) and National Institutes of Health (AR60304 and AR64735 to T.S.G., and AR057740 to S.J.W.)”
Note: The following three articles were made available online early in 2014, but are listed here to help fill in the Winter 2014 coverage gap for Current Awareness.
4
Camacho CV, Todorova PK, Hardebeck MC, Tomimatsu N, Gil Del Alcazar CR, Ilcheva M, Mukherjee B, McEllin B, Vemireddy V, Hatanpaa K, Story MD, Habib AA, Murty VV, Bachoo R, Burma S.
DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification.
http://www.ncbi.nlm.nih.gov/pubmed/24632607
(PI: S. Burma)
Journal Impact Factor: 8.559
Funding: “SB is supported by grants from the National Aeronautics and Space Administration (NNX13AI13G), National Institutes of Health (RO1 CA149461) and the Cancer Prevention and Research Institute of Texas (RP100644). AAH is supported by a National Institutes of Health grant (R01 NS062080). MCH is supported by a National Institute of General Medical Sciences training grant 5T32GM008203 in cellular and molecular biology. CVC was supported by a NCI training grant (T32CA124334).
5
Gil del Alcazar CR, Hardebeck MC, Mukherjee B, Tomimatsu N, Gao X, Yan J, Xie XJ, Bachoo R, Li L, Habib AA, Burma S.
Inhibition of DNA double-strand break repair by the dual PI3K/mTOR inhibitor NVP-BEZ235 as a strategy for radiosensitization of glioblastoma.
Clin Cancer Res. 2014 Mar 1;20(5):1235-48.
http://www.ncbi.nlm.nih.gov/pubmed/24366691
(PI: S. Burma)
Journal Impact Factor: 9.193
Funding: “S. Burma is supported by grants from the NIH (RO1 CA149461), the Cancer Prevention Research Institute of Texas (RP100644), and the National Aeronautics and Space Administration (NNX13AI13G). A.A. Habib is supported by a NIH grant (RO1 NS062080). M.C. Hardebeck is supported by a National Institute of General Medical Sciences training grant 5T32GM008203 in cellular and molecular biology. C.R. Gil del Alcazar completed this work in partial fulfillment of the requirements for his PhD degree.”
6
Tomimatsu N, Mukherjee B, Catherine Hardebeck M, Ilcheva M, Vanessa Camacho C, Louise Harris J, Porteus M, Llorente B, Khanna KK, Burma S.
Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice.
Nat Commun. 2014 Apr 7;5:3561.
http://www.ncbi.nlm.nih.gov/pubmed/24705021
(PI: S. Burma)
Note: This article may be obtained online without charge.
Journal Impact Factor: 10.742
Funding: “S.B. is supported by grants from the National Institutes of Health (RO1 CA149461), National Aeronautics and Space Administration (NNX13AI13G), and the Cancer Prevention and Research Institute of Texas (RP100644). K.K.K. is supported by a National Health and Medical Research Council Senior Principal Research Fellowship. B.L. is supported by a grant from Foundation ARC.”
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Other papers of interest:
1
Vaquer S, Cuyàs E, Rabadán A, González A, Fenollosa F, de la Torre R.
Active transmembrane drug transport in microgravity: A validation study using an ABC transporter model.
http://www.ncbi.nlm.nih.gov/pubmed/25520779
Note: Parabolic flight results. This article may be obtained online without charge.
2
Yi B, Matzel S, Feuerecker M, Hörl M, Ladinig C, Abeln V, Choukèr A, Schneider S.
The impact of chronic stress burden of 520-d isolation and confinement on the physiological response to subsequent acute stress challenge.
Behav Brain Res. 2014 Dec 12. pii: S0166-4328(14)00796-7. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25499619
Note: Mars520 isolation study.
3
Breus TK, Boiko ER, Zenchenko TA.
Magnetic storms and variations in hormone levels among residents of North Polar area – Svalbard.
Life Sci Space Res. 2014 Dec 23. [Article in Press]
http://www.sciencedirect.com/science/article/pii/S2214552414000650
4
Chacon A, Rabin J, Yu D, Johnston S, Bradshaw T.
Quantification of color vision using a tablet display.
Aerosp Med Human Perform. 2015 Jan;86(1):56-8.
http://ingentaconnect.com/content/asma/asem/2015/00000086/00000001/art00012
5
Sheppard RL, Regis DP, Mahon RT.
Dodecafluoropentane (DDFPe) and decompression sickness-related mortality in rats.
Aerosp Med Human Perform. 2015 Jan;86(1):21-6.
http://ingentaconnect.com/content/asma/asem/2015/00000086/00000001/art00007
6
Jang TY, Kim K-S, Park C-S, Lim J, Huh K-C, Heo M-J, Jung A-Y, Kim YH.
Exposure to hypergravity increases serum interleukin-5 and pulmonary infiltration in mice with allergic asthma.
Cent Eur J Immunol. 2014;39(4):434-40.
Note: Centrifugation was used. This article may be obtained online without charge.
7
Mantokoudis G, Saber Tehrani AS, Kattah JC, Eibenberger K, Guede CI, Zee DS, Newman-Toker DE.
Quantifying the vestibulo-ocular reflex with video-oculography: Nature and frequency of artifacts.
Audiol Neurootol. 2014 Dec 9;20(1):39-50. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25501133
Note: Citations 8-11 are a series of opinion pieces regarding mechanisms of disuse muscle atrophy. The series contains an opinion and an opposing view as well as rebuttals from both sets of authors.
8
Phillips SM, McGlory C.
CrossTalk proposal: The dominant mechanism causing disuse muscle atrophy is decreased protein synthesis.
J Physiol. 2014 Dec 15;592(Pt 24):5341-3.
http://www.ncbi.nlm.nih.gov/pubmed/25512435
Note: This article may be obtained online without charge.
9
Reid MB, Judge AR, Bodine SC.
CrossTalk opposing view: The dominant mechanism causing disuse muscle atrophy is proteolysis.
J Physiol. 2014 Dec 15;592(Pt 24):5345-7.
http://www.ncbi.nlm.nih.gov/pubmed/25512436
Note: This article may be obtained online without charge.
10
Phillips SM, McGlory C.
Rebuttal from Stuart M. Phillips and Chris McGlory.
J Physiol. 2014 Dec 15;592(Pt 24):5349.
http://www.ncbi.nlm.nih.gov/pubmed/25512437
Note: This article may be obtained online without charge.
11
Reid MB, Judge AR, Bodine SC.
Rebuttal from Michael B. Reid, Andrew R. Judge and Sue C. Bodine.
J Physiol. 2014 Dec 15;592(Pt 24):5351.
http://www.ncbi.nlm.nih.gov/pubmed/25512438
12
Maurer MM, Weinkamer R, Müller R, Ruffoni D.
Does mechanical stimulation really protect the architecture of trabecular bone? A simulation study.
Biomech Model Mechanobiol. 2014 Dec 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25501464
13
Wang A, Zang J, Wang J, Nie G, Zhao G, Chen B.
Excessive iron and weightlessness effects on the femurs and livers of rats.
Aerosp Med Human Perform. 2015 Jan;86(1):8-14.
http://ingentaconnect.com/content/asma/asem/2015/00000086/00000001/art00005
Note: Hindlimb unloading study.
14
Toma S, Sciutti A, Papaxanthis C, Pozzo T.
Visuo-motor adaptation to a visual rotation is gravity dependent.
J Neurophysiol. 2014 Dec 10:jn.00369.2014. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25505105
15
Fetisova EK, Antoschina MM, Cherepanynets VD, Izumov DS, Kireev II, Kireev RI, Lyamzaev KG, Riabchenko NI, Chernyak BV, Skulachev VP.
Radioprotective effects of mitochondria-targeted antioxidant SkQR1.
Radiat Res. 2014 Dec 12. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25496313
16
Meroz Y, Bastien R.
Stochastic processes in gravitropism.
Front Plant Sci. 2014 Nov 26;5:674. Review.
http://www.ncbi.nlm.nih.gov/pubmed/25505482
Note: This article may be obtained online without charge.
17
Lu Y, Ding C, Wang J, Shang P.
An illuminated growth system for the study of Arabidopsis thaliana during diamagnetic levitation by a superconducting magnet.
Adv Space Res. 2015 Jan 1;55(1):525-33.
http://www.sciencedirect.com/science/article/pii/S0273117714005857
18
Benoit L, Belin E, Dürr C, Chapeau-Blondeau F, Demilly D, Ducournau S, Rousseau D.
Computer vision under inactinic light for hypocotyl–radicle separation with a generic gravitropism-based criterion.
Comput Electron Agric. 2015 Feb;111:12-7.
http://www.sciencedirect.com/science/article/pii/S0168169914003111
19
Ren J, Liu L, Jin XL, Fu SL, Ding ZC.
Physiological and morphological responses induced by α-particle radiation on Arabidopsis thaliana embryos.
Genet Mol Res. 2014 Nov 12;13(4):9569-77.
http://www.ncbi.nlm.nih.gov/pubmed/25501166
20
Burke D, Kelly DJ.
A mechanobiological model of endothelial cell migration and proliferation.
Comput Methods Biomech Biomed Engin. 2014 Dec 16:1-10. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25513718
