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NASA Spaceline Current Awareness List #996 22 April 2022 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, April 22, 2022

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Shawna Byrd, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.
 
Call for articles to cite in the weekly lists: Authors at NASA Centers and NASA PIs—do you have an article that has recently published or will publish in the upcoming weeks within a peer-reviewed journal and is in the scope of space life sciences? If so, send it our way! Send your article to the email address mentioned above. Articles received by Wednesday will appear within that week's list—articles received after Wednesday will appear the following week.
 
Papers deriving from NASA support:
 
1
Marshall-Goebel K.
Neuro-ocular effects of spaceflight.
In: Handbook of Space Pharmaceuticals. Cham, Switzerland: Springer, 2022. p. 261-71. 978-3-030-05525-7.
https://doi.org/10.1007/978-3-030-05526-4_1
PI: K. Marshall-Goebel
Note: The spaceflight information is not evident in the available abstract.
Funding: "This work was supported by the Translational Research Institute through Cooperative Agreement NNX16AO69A."
 
2
Yule S, Robertson JM, Mormann B, Smink DS, Lipsitz S, Abahuje E, Kennedy-Metz L, Park S, Miccile C, Pozner CN, Doyle T, Musson D, Dias RD.
Research article in revision for human factors special issue: Human factors and ergonomics in space exploration crew autonomy during simulated medical event management on long duration space exploration missions.
Hum Factors. 2022 Apr 16:187208211067575. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/35430922
PI: S. Yule
Note: NASA Task Load Index assessment. From the article: "This was a randomized controlled trial in which participants formed teams of three members whose task was to manage a series of four simulated in-flight medical emergencies. Using a random number generator, teams were randomly assigned to one of two groups: with support from a Flight Surgeon (with FS) and without support from a Flight Surgeon (without FS). The spacecraft vehicle simulator and mission control console used in this study are located at the STRATUS Center for Medical Simulation at Brigham and Women's Hospital in Boston, MA, USA." This article may be obtained online without charge.
Journal Impact Factor: 2.888
Funding: "The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was funded through a research grant from the National Aeronautics and Space Administration, number 80NSSC19K0745."
 
3
Carbino B, Guy A, Durka M, Zakerzadeh R.
The effects of geometric features of intraluminal thrombus on the vessel wall oxygen deprivation.
Front Bioeng Biotechnol. 2022 Mar 28;10:814995.
https://pubmed.ncbi.nlm.nih.gov/35419349
Note: This article is part of Research Topic "Hemodynamic Forces and Endothelial Mechanobiology in Vascular Diseases" (https://www.frontiersin.org/research-topics/20516/hemodynamic-forces-and-endothelial-mechanobiology-in-vascular-diseases#articles). This article may be obtained online without charge.
Journal Impact Factor: 5.890
Funding: M. Durka is affiliated with NASA Jet Propulsion Laboratory.
 
___________________________________________________
 
 
Other papers of interest:
 
1
Waisberg E, Ong J, Zaman N, Kamran SA, Lee AG, Tavakkoli A.
A non-invasive approach to monitor anemia during long-duration spaceflight with retinal fundus images and deep learning.
Life Sci Space Res. 2022 Apr 19. Online ahead of print.
https://doi.org/10.1016/j.lssr.2022.04.004
Note: From the abstract: "During spaceflight, astronauts can experience significantly higher levels of hemolysis. With future space missions exposing astronauts to longer periods of microgravity, such as missions to Mars, there will be a need to for better understanding this phenomenon. We have proposed that retinal fundus photography and deep learning may be utilized to help further understand this microgravity-induced, anemic process for future spaceflight. By utilizing astronaut and terrestrial analog metadata, a foundation can be built to develop an algorithm that allows for non-invasive retinal imaging to quantify hemoglobin levels and detect anemia during spaceflight. This approach would allow for a non-invasive retinal photograph that can be done frequently during spaceflight as opposed to an invasive blood draw and subsequent tests."
 
2
Yusupova A, Supolkina N, Shved D, Gushin V, Nosovsky A, Savinkina A.
Subjective perception of time in space flights and analogs.
Acta Astronaut. 2022 Apr 18. Online ahead of print.
https://doi.org/10.1016/j.actaastro.2022.04.016
Note: From the abstract: "A number of studies have shown that under certain conditions, perception of time tends to change. In isolation experiments, under monotony, time seems to slow down. In space flight, especially under stress of first days of flight, time seems to run too fast, and it is difficult for the cosmonauts to keep up with the schedule. Earth has to make special scheduling for the cosmonauts, taking into account the difficulties linked to microgravity and stress. Since 2015 we've been studying communication using content analysis of crew's communication with [multi-crew coordination] MCC that is happening through open channels."
 
3
Dixit J, Jagtap S, Vidyasagar P.
Short-term hypergravity-induced changes in growth, photo synthetic parameters, and assessment of threshold values in wheat (Triticum aestivum L.).
Gravit Space Res. 2022 Apr 12;10(1):10-7.
https://doi.org/10.2478/gsr-2022-0002
Note: From the abstract: "The reduction in growth and development of plants constantly exposed to different ranges of hypergravity (acceleration more than 1 g) is adequately documented. However, earlier studies did not reveal the threshold hypergravity value at which these effects were seen.The understanding of the threshold g-value is an important consideration while we plan hypergravity experiments as different plants can perceive and respond differently at the same g-value. The aim of the present work is to study the effect on growth and photosynthetic parameters as well as to assess the threshold values in wheat seedlings grown from hypergravity-exposed seeds." This article may be obtained online without charge.
 
4
Pannico A, Cimini G, Quadri C, Paradiso R, Bucchieri L, Rouphael Y, De Pascale S.
A plant characterization unit for closed life support: Hardware and control design for atmospheric systems.
Front Astron Space Sci. 2022 Apr 14;9:820752.
https://doi.org/10.3389/fspas.2022.820752
Note: This article is part of Research Topic "Bioregenerative Life-Support Systems for Crewed Missions to the Moon and Mars" (https://www.frontiersin.org/research-topics/16705/bioregenerative-life-support-systems-for-crewed-missions-to-the-moon-and-mars#articles). The Research Topic also includes articles from previous Current Awareness Lists #960 https://doi.org/10.3389/fspas.2021.699688, https://doi.org/10.3389/fmicb.2021.699525, https://doi.org/10.3389/fspas.2021.700370, https://doi.org/10.3389/fspas.2021.711550,https://doi.org/10.3389/fmicb.2021.700010, https://doi.org/10.3389/fspas.2021.700579, and https://doi.org/10.3389/fspas.2021.699097; #961 https://doi.org/10.3389/fspas.2021.665649; #962 https://doi.org/10.3389/fspas.2021.700270; #964 https://doi.org/10.3389/fmicb.2021.709746; #975 https://doi.org/10.3389/fmicb.2021.700810; #979 https://doi.org/10.3389/fmicb.2021.733244; #987 https://doi.org/10.3389/fspas.2021.734343, https://doi.org/10.3389/fspas.2021.733944, and https://doi.org/10.3389/fspas.2021.747821. This article may be obtained online without charge.
 
5
Topolski C, Divo E, Li X, Hicks J, Chavez A, Castillo H.
Phenotypic and transcriptional changes in Escherichia coli K12 in response to simulated microgravity on the EagleStat, a new 2D microgravity analog for bacterial studies.
Life Sci Space Res. 2022 Apr 18. Online ahead of print.
https://doi.org/10.1016/j.lssr.2022.04.003
Note: A 2D clinostat was used in this study.
 
6
Belaidi E, Khouri C, Harki O, Baillieul S, Faury G, Briançon-Marjollet A, Pépin JL, Arnaud C.
Cardiac consequences of intermittent hypoxia: A matter of dose? A systematic review and meta-analysis in rodents.
Eur Respir Rev. 2022 Jun 30;31(164):210269. Review.
https://pubmed.ncbi.nlm.nih.gov/35418489
Note: This article may be obtained online without charge.
 
7
Horiuchi M, Nishida A, Dobashi S, Koyama K.
Comparisons between normobaric normoxic and hypoxic recovery on post-exercise hemodynamics after sprint interval cycling in hypoxia.
Front Physiol. 2022 Mar 24;13:843574.
https://pubmed.ncbi.nlm.nih.gov/35399262
Note: This article is part of Research Topic "Near-Infrared Spectroscopy Technique and its Application in Exercise Settings" (https://www.frontiersin.org/research-topics/19329/near-infrared-spectroscopy-technique-and-its-application-in-exercise-settings#articles). This article may be obtained online without charge.
 
8
Cai S, Yang Y, Kong Y, Guo Q, Xu Y, Xing P, Sun Y, Qian J, Xu R, Xie L, Hu Y, Wang M, Li M, Tian Y, Mao W.
Gut bacteria Erysipelatoclostridium and its related metabolite ptilosteroid A could predict radiation-induced intestinal injury.
Front Public Health. 2022 Mar 28;10:862598.
https://pubmed.ncbi.nlm.nih.gov/35419331
Note: This article is part of Research Topic "Astroparticle Experiments to Improve the Biological Risk Assessment of Exposure to Ionizing Radiation in the Exploratory Space Missions" (https://www.frontiersin.org/research-topics/28918/astroparticle-experiments-to-improve-the-biological-risk-assessment-of-exposure-to-ionizing-radiatio#articles). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.
 
9
Nakaji-Hirabayashi T, Matsumura K, Ishihara R, Ishiguro T, Nasu H, Kanno M, Ichida S, Hatashima T.
Enhanced proliferation and differentiation of human mesenchymal stem cells in the gravity-controlled environment.
Artif Organs. 2022 Apr 11. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/35403254
Note: From the abstract: "Human bone marrow mesenchymal stem cells (hMSCs) present a promising cell source with a potential to be used for curing various intractable diseases. And it is expected that the development of regenerative medicine employing cell-based therapy would be significantly accelerated when such methods are established. For that, powerful methods for selective growth and differentiation of hMSCs should be developed."
 
10
Pemov A, Kim J, Jones K, Vogt A, Sadetzki S, Stewart DR.
Examination of genetic susceptibility in radiation-associated meningioma.
Radiat Res. 2022 Apr 11. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/35405740
 
11
Tandl D, Sponagel T, Alansary D, Fuck S, Smit T, Hehlgans S, Jakob B, Fournier C, Niemeyer BA, Rödel F, Roth B, Moroni A, Thiel G.
X-ray irradiation triggers immune response in human T-lymphocytes via store-operated Ca2+ entry and NFAT activation.
J Gen Physiol. 2022 May 2;154(5):e202112865.
https://pubmed.ncbi.nlm.nih.gov/35416945
Note: This article may be obtained online without charge.
 
12
Villagomez-Bernabe B, Chan SW, Coulter JA, Roseman AM, Currell FJ.
Fast ion-beam inactivation of viruses, where radiation track structure meets RNA structural biology.
Radiat Res. 2022 Apr 18. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/35436347
 
13
Chu TH, Vo MC, Lakshmi TJ, Ahn SY, Kim M, Song GY, Yang DH, Ahn JS, Kim HJ, Jung SH, Lee JJ.
Novel IL-15 dendritic cells have a potent immunomodulatory effect in immunotherapy of multiple myeloma.
Transl Oncol. 2022 June;20:101413.
https://pubmed.ncbi.nlm.nih.gov/35413499
Note: This article may be obtained online without charge.
 
14
Dislich B, Mertz KD, Gloor B, Langer R.
Interspatial distribution of tumor and immune cells in correlation with PD-L1 in molecular subtypes of gastric cancers.
Cancers (Basel). 2022 Mar 29;14(7):1736.
https://pubmed.ncbi.nlm.nih.gov/35406506
Note: This article is part of Special Issue "Feature Paper from Journal Reviewers" (https://www.mdpi.com/journal/cancers/special_issues/reviewer). This article may be obtained online without charge.
 
15
Jochem C, Leitzmann M.
Physical activity and sedentary behavior in relation to cancer survival: A narrative review.
Cancers (Basel). 2022 Mar 28;14(7):1720. Review.
https://pubmed.ncbi.nlm.nih.gov/35406492
Note: From the abstract: "From a public health perspective, cancer is a major issue, and it contributes to a high economic and societal burden. Lifestyle-associated risk factors play a crucial role in cancer prevention. The present narrative review aims to summarize the existing evidence on the relationship of physical activity and sedentary behavior to cancer survival, including the evidence on mortality and other health-related outcomes." This article may be obtained online without charge.
 
16
Mantilla-Rojas C, Velasquez FC, Morton JE, Clemente LC, Parra ER, Torres-Cabala C, Sevick-Muraca EM.
Enhanced T-cell priming and improved anti-tumor immunity through lymphatic delivery of checkpoint blockade immunotherapy.
Cancers (Basel). 2022 Apr 4;14(7):1823.
https://pubmed.ncbi.nlm.nih.gov/35406595
Note: This article may be obtained online without charge.
 
17
Rigoni I, Bonci T, Bifulco P, Fratini A.
Characterisation of the transient mechanical response and the electromyographical activation of lower leg muscles in whole body vibration training.
Sci Rep. 2022 Apr 14;12:6232.
https://pubmed.ncbi.nlm.nih.gov/35422059
Note: This article may be obtained online without charge.
 
18
Shugaba A, Lambert JE, Bampouras TM, Nuttall HE, Gaffney CJ, Subar DA.
Should all minimal access surgery be robot-assisted? A systematic review into the musculoskeletal and cognitive demands of laparoscopic and robot-assisted laparoscopic surgery.
J Gastrointest Surg. 2022 Apr 14. Review.
https://pubmed.ncbi.nlm.nih.gov/35426034
Note: From the abstract: "Surgeons are among the most at risk of work-related musculoskeletal health decline because of the physical demands of surgery, which is also associated with cognitive fatigue. Minimally invasive surgery offers excellent benefits to patients but the impact of robotic or laparoscopic surgery on surgeon well-being is less well understood. This work examined the musculoskeletal and cognitive demands of robot-assisted versus standard laparoscopic surgery." This article may be obtained online without charge.
 
19
Liu K, Liu Y, Cai F, Fan C, Ren P, Yusufu A.
Efficacy comparison of trifocal bone transport using unilateral external fixator for femoral and tibial bone defects caused by infection.
BMC Surg. 2022 Apr 12;22(1):141.
https://pubmed.ncbi.nlm.nih.gov/35413897
Note: This article may be obtained online without charge.
 
20
Perier-Metz C, Cipitria A, Hutmacher DW, Duda GN, Checa S.
An in silico model predicts the impact of scaffold design in large bone defect regeneration.
Acta Biomater. 2022 Apr 10;S1742-7061(22)00213-6. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/35417799
 
21
Du J, Huang Y, Zhao Z, Wang Y, Xu S, Zhang R, Xiao L, Xu J, Wang H, Su T, Tang Y.
Planning ability and alertness after nap deprivation: Beneficial effects of acute moderate-intensity aerobic exercise greater than sitting naps.
Front Public Health. 2022 Mar 24;10:861923.
https://pubmed.ncbi.nlm.nih.gov/35400075
Note: This article is part of Research Topic "Association of Physical Activity and Fitness with Mental Health Outcomes: Current Advances and Future Directions" (https://www.frontiersin.org/research-topics/26448/association-of-physical-activity-and-fitness-with-mental-health-outcomes-current-advances-and-future#articles). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.
 
22
Miyake T, Egawa G, Chow Z, Asahina R, Otsuka M, Nakajima S, Nomura T, Shibuya R, Ishida Y, Nakamizo S, Murata T, Kitoh A, Kabashima K.
Circadian rhythm affects the magnitude of contact hypersensitivity response in mice.
Allergy. 2022 Apr 15. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/35426135
 
23
Voldsbekk I, Bjørnerud A, Groote I, Zak N, Roelfs D, Maximov, II, Geier O, Due-Tønnessen P, Bøen E, Kuiper YS, Løkken LL, Strømstad M, Blakstvedt TY, Bjorvatn B, Malt UF, Westlye LT, Elvsåshagen T, Grydeland H.
Evidence for widespread alterations in cortical microstructure after 32 h of sleep deprivation.
Transl Psychiatry. 2022 Apr 14;12:161.
https://pubmed.ncbi.nlm.nih.gov/35422097
Note: This article may be obtained online without charge.
 
24
Wellman LL, Lonart G, Adkins AM, Sanford LD.
Regulation of dark period sleep by the amygdala: A microinjection and optogenetics study.
Brain Res. 2022 Apr 15;1781:147816.
https://pubmed.ncbi.nlm.nih.gov/35131286
 
25
Chen J, Cao Z, Cannon J, Fan Y, Baker JR, Jr., Wang SH.
Effective treatment of skin wounds co-infected with multidrug-resistant bacteria with a novel nanoemulsion.
Microbiol Spectr. 2022 Apr 12;e0250621. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/35412373
Note: This article may be obtained online without charge.
 
26
Delafontaine A, Vialleron T, Diakhaté DG, Fourcade P, Yiou E.
Effects of experimentally induced cervical spine mobility alteration on the postural organisation of gait initiation.
Sci Rep. 2022 Apr 11;12:6055.
https://pubmed.ncbi.nlm.nih.gov/35410364
Note: This article may be obtained online without charge.
 
27
Fadillioglu C, Kanus L, Möhler F, Ringhof S, Hellmann D, Stein T.
Influence of controlled stomatognathic motor activity on sway, control and stability of the center of mass during dynamic steady-state balance-An uncontrolled manifold analysis.
Front Hum Neurosci. 2022 Mar 25;16:868828.
https://pubmed.ncbi.nlm.nih.gov/35399352
Note: This article and the article below (J. Heil) are part of Research Topic "Acute and chronic changes in postural control in response to different physiological states and external environmental conditions" (https://www.frontiersin.org/research-topics/22905/acute-and-chronic-changes-in-postural-control-in-response-to-different-physiological-states-and-exte#articles). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.
 
28
Heil J.
Load-induced changes of inter-limb asymmetries in dynamic postural control in healthy subjects.
Front Hum Neurosci. 2022 Mar 11;16:824730.
https://pubmed.ncbi.nlm.nih.gov/35360281
Note: This article and the article above (Fadillioglu et al.) are part of Research Topic "Acute and chronic changes in postural control in response to different physiological states and external environmental conditions" (https://www.frontiersin.org/research-topics/22905/acute-and-chronic-changes-in-postural-control-in-response-to-different-physiological-states-and-exte#articles). This article may be obtained online without charge.
 

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