In case you missed it:Theastrobiology webwebsite features an article titled, "Researchers Put Space Garden Microbes Under the Microscope," discussing how NASA scientists are carefully monitoring the microbiome of the International Space Station with two goals in mind—to map and keep track of microbes present through time, and to discover any patterns of microbial growth that could potentially affect the crew's health and safety—in order to determine whether or not the station itself creates conditions that spur microbial growth. Further reading is available athttp://astrobiology.com/2021/12/researchers-put-space-garden-microbes-under-the-microscope.html.
Papers deriving from NASA support:
Haveman NJ, Schuerger AC.
Diagnosing an opportunistic fungal pathogen on spaceflight-grown plants using the MinION sequencing platform.
PI:N.J. Haveman, NASA Space Biology Postdoctoral Fellowship
Note:ISS results. From the abstract: "In this study, we show how the MinION sequencing platform can be used to diagnose the opportunistic pathogen,Fusarium oxysporum sensulato; a fungal infection onZinnia hybrida(zinnia) plants that were grown on the International Space Station (ISS) in 2015–2016."
Journal Impact Factor:4.335
Funding:"This study was supported in part by NASA Space Biology Postdoctoral Fellowship (80NSSC19K0520) awarded to N.J.S."
Note:From the abstract: "This study extends previous findings by analyzing how spaceflight affects characteristics of sleep spindles and slow waves, two sleep oscillations associated with sleep quality and quantity, in four astronauts before, during and after two Space Shuttle missions." This article may be obtained online without charge.
Journal Impact Factor:4.415
Funding:"We thank the Space Shuttle crew members who participated in this study; Dr. Leopold Summerer and ESA’s Advanced Concepts Team for their help in initiating and running this study; Dr. R. Hughes for his role in the original study; NASA’s LSDA, LSAH, and IRB teams, as well as Inês Antunes, ESA’s Human Research Science Coordinator, for their continuous support. Dr. Flynn-Evans was supported by the NASA Human Research Program. Drs. Barger and Czeisler and Mr. Sullivan were supported in part by R01OH011773."
Bretl KN, Clark TK.
Predicting individual acclimation to the cross-coupled illusion for artificial gravity.
Note:From the abstract: "Eleven subjects were exposed to the CC illusion for up to 50 25-minute acclimation sessions. The metric of acclimation rate was calculated as the slope of each subject's linear increase in spin rate across sessions. As potential predictors of acclimation rate, we gathered age, gender, demographics, and activity history, and measured subjects' vestibular perceptual thresholds in the yaw, pitch, and roll rotation axes."
Journal Impact Factor:2.435
Funding:"The funding for this research was provided via a NASA Space Technology Research Fellowship, Grant Number 80NSSCK0085."
Kiffer FC, Luitel K, Tran FH, Patel RA, Guzman CS, Soler I, Xiao R, Shay JW, Yun S, Eisch AJ.
Effects of a 33-ion sequential beam galactic cosmic ray analog on male mouse behavior and evaluation of CDDO-EA as a radiation countermeasure.
PIs:J.W. Shay, S. Yun, A.J. Eisch, F.C. Kiffer, TRISH Postdoctoral Program Fellowship
Journal Impact Factor:3.332
Funding:"This work was supported by NASA grants 80NSSC17K0060 (Eisch), 80NSSC21K0814 (Yun), NNX16AE08G (Shay); by the Translational Research Institute for Space Health through NASA cooperative agreement NNX16AO69A (Kiffer); NIH MH107945 (Eisch and Yun); the University of Pennsylvania McCabe Fund (Yun); the NARSAD Brain & Behavior Research Foundation award for Young Investigators (Yun); the Children’s Hospital of Philadelphia Department of Anesthesiology and Critical Care Development Fund (Eisch)."
De Martino E, Hides J, Elliott JM, Hoggarth MA, Zange J, Lindsay K, Debuse D, Winnard A, Beard D, Cook JA, Salomoni SE, Weber T, Scott J, Hodges PW, Caplan N.
Intramuscular lipid concentration increased in localized regions of the lumbar muscles following 60-day bedrest.
Spine J. 2021 Nov 20;S1529-9430(21)01028-7. Online ahead of print.
Note:Head-down tilt bedrest study. This article may be obtained online without charge.
Journal Impact Factor:4.166
Funding:"The AGBRESA study was funded by the German Aerospace Center, the European Space Agency (contract number: 4000113871/15/NL/PG), and the National Aeronautics and Space Administration (contract number: 80JSC018P0078). The study was performed at the ":envihab" research facility of the DLR Institute of Aerospace Medicine. Funding for this ESA-selected project (ESA-HSO-U-LE-0629) was received from the STFC/UK Space Agency (ST/R005753/1)."
Yamazaki EM, Antler CA, Casale CE, MacMullen LE, Ecker AJ, Goel N.
Cortisol and C-reactive protein vary during sleep loss and recovery but are not markers of neurobehavioral resilience.
Funding:"This work was supported by the National Aeronautics and Space Administration (NASA) [grant numbers NNX14AN49G and 80NSSC20K0243 (to NG)]. This work was also partially supported from National Institutes of Health [grant number NIH R01DK117488 (to NG)]."
Plante I, Poignant F, Slaba T.
Track structure components: Characterizing energy deposited in spherical cells from direct and peripheral HZE ion hits.
Note:From the abstract: "To understand the biological effects of radiation, it is important to determine how ionizing radiation deposits energy in micrometric targets. The energy deposited in a target located in an irradiated tissue is a function of several factors such as the radiation type and the irradiated volume size. We simulated the energy deposited by energetic ions in spherical targets of 1, 2, 4, and 8 µm radii encompassed in irradiated parallelepiped volumes of various sizes using the stochastic radiation track structure code Relativistic Ion Tracks (RITRACKS)." This article and an article below in the "Other" section (Calvaruso et al.) are part of Special Issue "Space Radiobiology" (https://www.mdpi.com/journal/life/special_issues/space_radiobiology). The Special Issue also includes an article from previous Current Awareness List #968https://doi.org/10.3390/life11080849. Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
Journal Impact Factor:3.817
Funding:"This work was supported by NASA Human Health and Performance (HHPC) contract number NNJ15HK11B (I.P.) and by the NASA Langley Cooperative Agreement 80LARC17C0004 (F.P.). This work is supported by the Human Research Program under the Human Exploration and Operations Mission Directorate at NASA (T.S.)."
Roberts DR, Collins HR, Al Kasab S.
The importance of the intracranial compartment in the development of spaceflight-associated neuro-ocular syndrome.
JAMA Ophthalmol. 2021 Nov 24. Online ahead of print.
Note:From the abstract: "This review aims to elucidate the detailed molecular mechanisms and genetic mutations found in plants used in recent space crop projects and how these can be applied in space breeding programs in the future." This article is part of the Research Topic "Enviromics in Plant Breeding" (https://www.frontiersin.org/research-topics/17196/enviromics-in-plant-breeding#articles). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.
Strigari L, Strolin S, Morganti AG, Bartoloni A.
Dose-effects models for space radiobiology: An overview on dose-effect relationships.
Note:From the abstract: "In our study, we aimed to characterize, at the biological and mechanical level, a Random Positioning Machine in order to simulate microgravity in an in vitro model of Triple-Negative Breast Cancer (TNBC)." This is article and an article above in the "NASA" section (Plante et al.) are part of Special Issue "Space Radiobiology" (https://www.mdpi.com/journal/life/special_issues/space_radiobiology). This article may be obtained online without charge.
Guillon L, Kermorgant M, Charvolin T, Bonneville F, Bareille M-P, Cassol E, Beck A, Beaurain M, Péran P, Lotterie J-A, Traon AP-L, Payoux P.
Note:From the abstract: "…this study investigated lower limb joint kinematics and gastrocnemius medialis behavior during running at 1 g, simulated Martian gravity, and simulated Lunar gravity on the vertical treadmill facility." This article may be obtained online without charge.
Abdelfattah OM, Sayed A, Elgendy IY, Munir M, Saleh Y, Kapadia SR, Abela GS, Jneid H.
Patent foramen ovale closure and decompression sickness among divers.
Cardiovasc Revasc Med. 2021 Nov 20;S1553-8389(21)00745-4. Online ahead of print.
Note:From the abstract: "Humans and animals learn the internal model of bodies and environments from their experience and stabilize posture against disturbances based on the predicted future states according to the internal model. We evaluated the mechanism of predictive control during standing, by using rats to construct a novel experimental system and comparing their behaviors with a mathematical model." This article is part of Research Topic "The Neural Basis of Hyper-Adaptability in Humans and Animals" (https://www.frontiersin.org/research-topics/18103/the-neural-basis-of-hyper-adaptability-in-humans-and-animals#articles). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.
Bodnyk KA, Kim DG, Pan X, Hart RT.
The long-term residual effects of low-magnitude mechanical stimulation on murine femoral mechanics.
J Biomech Eng. 2021 Nov 24. Online ahead of print.
Note:From the abstract: "As an alternative to drug treatments, low-magnitude mechanical stimulation (LMMS) may improve skeletal health without potential side effects from drugs. LMMS has been shown to increase bone health short term in both animal and clinical studies. Long term changes to the mechanical properties of bone from LMMS are currently unknown, so the objective of this research is to investigate the long-term effects of whole body vibration therapy on the elastic and viscoelastic properties of bone."
Harijanto C, Lim A, Vogrin S, Duque G.
Does whole-body vibration training have a concurrent effect on bone and muscle health? A systematic review and meta-analysis.
Gerontology. 2021 Nov 15;1-11. Online ahead of print.