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NASA Spaceline Current Awareness List #898 8 May 2020 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, May 8, 2020

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

 

Papers deriving from NASA support:

 

 

1

Avila-Herrera A, Thissen J, Urbaniak C, Be NA, Smith DJ, Karouia F, Mehta S, Venkateswaran K, Jaing C.

Crewmember microbiome may influence microbial composition of ISS habitable surfaces.

PLoS One. 2020 Apr 29;15(4):e0231838.

https://pubmed.ncbi.nlm.nih.gov/32348348

PIs: C. Jaing, K. Venkateswaran

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: 2.776

Funding: "Aram Avila-Herrera, James Thissen, Nicholas A Be, Crystal Jaing were funded by NASA Space Biology under contract #: 80NSSC18K0113....Camilla Urbaniak and Kasthuri Venkateswaran were funded by NASA Space Biology Task Plan #47-700062....Satish Mehta was funded by NASA Space Biology under contract #: 80NSSC18K0113. David J Smith was funded by NASA Ames Space Biology program....Fathi Karouia was supported through the KBRwyle/FILMSS subcontract with the Department of Pharmaceutical Chemistry at the University of California San Francisco, # NNA14AB82C, at NASA Ames Research Center."

 

2

Qin YX, Hu M, Li X.

Biomechanics of bone and cartilage.

In: Cheng CK, Woo SLY, eds. Frontiers in Orthopaedic Biomechanics. Singapore: Springer, 2020. p. 1-35.

https://link.springer.com/chapter/10.1007/978-981-15-3159-0_1

PI: Y.X. Qin

Journal Impact Factor: Not applicable to this publication

Funding: "This research was supported by the National Institutes of Health (R01 AR52379, AR61821, and AR49286), and the National Space Biomedical Research Institute through a NASA Cooperative Agreement NCC 9-58."

 

3

Prins TJ, Myers ZA, Saldate JJ, Hoffman LF.

Calbindin expression in adult vestibular epithelia.

J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2020 Apr 29. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32350587

PI: L.R. Hoffman

Journal Impact Factor: 1.882

Funding: "This investigation was made possible by funding from the National Aeronautics and Space Administration (NNX13AL99G) and the Victor Goodhill Ear Center."

 

4

Carter DR, Cullen-Lester KL, Jones JM, Gerbasi A, Chrobot-Mason D, Nae EY.

Functional leadership in interteam contexts: Understanding 'what' in the context of why? where? when? and who?

Leadersh Q. 2020 Feb;31(1):101378. Review.

http://www.sciencedirect.com/science/article/pii/S1048984318308403

PI: D.R. Carter

Note: This article may be obtained online without charge.

Journal Impact Factor: 5.631

Funding: "The development of this paper was supported in part by funding from the National Science Foundation (SES, #1853470, #1853404), the National Institutes of Health (NIH, #UL1TR002378), and the National Aeronautics and Space Administration (NASA, #80NSSC18K0511)."

 

5

Romero E, Francisco D.

The NASA human system risk mitigation process for space exploration.

Acta Astronaut. 2020 Apr 28. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0094576520302617

Note: From the abstract: "This paper describes NASA's innovative approach to assess and mitigate astronaut health and performance risks for space exploration missions beyond Low-Earth Orbit, with Mars as the focal destination."

Journal Impact Factor: 2.482

Funding: No funding cited. E. Romero is affiliated with NASA Johnson Space Center, D. Francisco is affiliated with NASA Headquarters.

______________________________________________________

 

 

Other papers of interest:

 

1

Sychev VN, Novikova ND, Poddubko SV, Deshevaya EA, Orlov OI.

The biological threat: The threat of planetary quarantine failure as a result of outer space exploration by humans.

Dokl Biol Sci. 2020 Jan;490(1):28-30.

https://pubmed.ncbi.nlm.nih.gov/32342323

Note: ISS results.

 

2

Chandler JO, Haas FB, Khan S, Bowden L, Ignatz M, Enfissi EMA, Gawthrop F, Griffiths A, Fraser PD, Rensing SA, Leubner-Metzger G.

Rocket science: The effect of spaceflight on germination physiology, ageing, and transcriptome of Eruca sativa seeds.

Life (Basel). 2020 Apr 24;10(4):E49.

https://pubmed.ncbi.nlm.nih.gov/32344775

Note: ISS results. This article may be obtained online without charge.

 

3

Leacy JK, O'Halloran KD, Day TA.

Simulating the space station: A launch pad for new explorations in integrative physiology.

J Physiol. 2020 Apr 29. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32347549

Note: Head-down tilt bed rest study.

 

4

Grimm D, Wehland M, Corydon TJ, Richter P, Prasad B, Bauer J, Egli M, Kopp S, Lebert M, Krüger M.

The effects of microgravity on differentiation and cell growth in stem cells and cancer stem cells.

Stem Cells Transl Med. 2020 Apr 30. [Epub ahead of print] Review.

https://pubmed.ncbi.nlm.nih.gov/32352658

Note: Studies discussed were conducted on the ISS as well as using rotating wall vessels, the Rotary Cell Culture System, random positioning machines, and clinostats. This article may be obtained online without charge.

 

5

Lin X, Zhang K, Wei D, Tian Y, Gao Y, Chen Z, Qian A.

The impact of spaceflight and simulated microgravity on cell adhesion.

Int J Mol Sci. 2020 Apr 25;21(9):E3031. Review.

https://pubmed.ncbi.nlm.nih.gov/32344794

Note: Modes of microgravity used in the studies reviewed include spaceflight, parabolic flight, sounding rockets, hindlimb unloading, the Rotary Cell Culture System, clinostats, and random positioning machines. This article may be obtained online without charge.

 

6

Robin A, Auvinet A, Degryse B, Murphy R, Bareille M-P, Beck A, Gharib C, Gauquelin-Koch G, Daviet A, Larcher F, Custaud M-A, Navasiolava N.

DI-5-CUFFS: Venoconstrictive thigh cuffs limit body fluid changes but not orthostatic intolerance induced by a 5-day dry immersion.

Front Physiol. 2020 May 5;11:383.

https://www.frontiersin.org/article/10.3389/fphys.2020.00383

Note: Dry immersion was used. This article may be obtained online without charge.

 

7

Akiyama T, Horie K, Hinoi E, Hiraiwa M, Kato A, Maekawa Y, Takahashi A, Furukawa S.

How does spaceflight affect the acquired immune system?

npj Microgravity. 2020 May 7;6(1):14. Review.

https://www.nature.com/articles/s41526-020-0104-1

Note: Studies discussed are not specified, but were conducted during spaceflight and using ground-based simulation methods. This article may be obtained online without charge.

 

8

Elwy R, Soliman MA, Hasanain AA, Ezzat AA, Elbaroody M, Alsawy MF, El Refaee E.

Visual changes after space flight: Is it really caused by increased intracranial tension? A systematic review.

J Neurosurg Sci. 2020 Apr 29. [Epub ahead of print] Review.

https://pubmed.ncbi.nlm.nih.gov/32347675

Note: From the abstract: "Our aim is to provide a comprehensive qualitative analysis of literature contrasting simulation and spaceflight studies, focusing on the pathophysiology of SANS, and highlighting gaps in current knowledge."

 

9

Händel A, Stern C, Jordan J, Dietlein T, Enders P, Cursiefen C.

[Eye changes in space: New insights into clinical aspects, pathogenesis and prevention].

Ophthalmologe. 2020 Apr 28. German. [Epub ahead of print] German. Review.

https://pubmed.ncbi.nlm.nih.gov/32347333

Note: Spaceflight results are reviewed.

 

10

Malatesta M, Costanzo M, Cisterna B, Zancanaro C.

Satellite cells in skeletal muscle of the hibernating dormouse, a natural model of quiescence and re-activation: Focus on the cell nucleus.

Cells. 2020 Apr 23;9(4):E1050.

https://pubmed.ncbi.nlm.nih.gov/32340154

Note: This article may be obtained online without charge.

 

11

Teigen LE, Sundberg CW, Kelly LJ, Hunter SK, Fitts RH.

Ca2+ dependency of limb muscle fiber contractile mechanics in young and older adults.

Am J Physiol Cell Physiol. 2020 Apr 29. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32348175

 

12

Liu HY, Zhao S, Zhang H, Huang SY, Peng WT, Zhang CQ, Wang W.

Research on solute transport behaviors in the lacunar-canalicular system using numerical simulation in microgravity.

Comput Biol Med. 2020 Apr;119:103700.

https://pubmed.ncbi.nlm.nih.gov/32339112

Note: From the abstract: "A multi-scale 3D fluid-solid coupled finite element model of osteon with a two-stage pore structure was developed using COMSOL software in order to investigate solute transport behaviors in the lacunar-canalicular system (LCS) induced by physiological strain loading."

 

13

Stavnichuk M, Mikolajewicz N, Corlett T, Morris MB, Komarova SV.

A systematic review and meta-analysis of bone loss in space travelers.

npj Microgravity. 2020 May 5;6(1):13. Review.

https://www.nature.com/articles/s41526-020-0103-2

Note: From the abstract: "…we used a meta-analytic approach to combine systematically identified data reporting measurements of bone density or biochemical bone markers in humans who have been to space according to the Fédération Aéronautique Internationale (FAI) definition." This article may be obtained online without charge.

 

14

Takemura A, Pajevic PD, Egawa T, Teshigawara R, Hayashi T, Ishihara A.

Effects of mild hyperbaric oxygen on osteoporosis induced by hindlimb unloading in rats.

J Bone Miner Metab. 2020 Apr 29. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32350615

Note: Hindlimb unloading study.

 

15

Furukawa S, Nagamatsu A, Nenoi M, Fujimori A, Kakinuma S, Katsube T, Wang B, Tsuruoka C, Shirai T, Nakamura AJ, Sakaue-Sawano A, Miyawaki A, Harada H, Kobayashi M, Kobayashi J, Kunieda T, Funayama T, Suzuki M, Miyamoto T, Hidema J, Yoshida Y, Takahashi A.

Space radiation biology for "living in space."

Biomed Res Int. 2020 Apr 8;2020:4703286. Review.

https://pubmed.ncbi.nlm.nih.gov/32337251

Note: This article may be obtained online without charge.

 

16

Nakajima K, Gao T, Kume K, Iwata H, Hirai S, Omachi C, Tomita J, Ogino H, Naito M, Shibamoto Y.

Fruit fly, Drosophila melanogaster, as an in vivo tool to study the biological effects of proton irradiation.

Radiat Res. 2020 Apr 28. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32343638

 

17

Vidal LM, Pimentel E, Cruces MP, Sánchez-Meza JC.

Evaluating the effect of low dose rate of gamma rays in germ cells of Drosophila melanogaster.

Int J Radiat Biol. 2020 Apr 27. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32338555

 

18

Xu H, Liu Y, Li Y, Diao L, Xun Z, Zhang Y, Wang Z, Li D.

RadAtlas 1.0: A knowledgebase focusing on radiation-associated genes.

Int J Radiat Biol. 2020 Apr 27. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32338561

 

19

White O, Gaveau J, Bringoux L, Crevecoeur F.

The gravitational imprint on sensorimotor planning and control.

J Neurophysiol. 2020 Apr 29. [Epub ahead of print] Review.

https://pubmed.ncbi.nlm.nih.gov/32348686

 

20

Patel T, Ivo J, Faisal S, McDougall A, Carducci J, Pritchard S, Chang F.

A prospective study of usability and workload of electronic medication adherence products by older adults, caregivers, and health care providers.

J Med Internet Res. 2020 Mar 28. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32348292

Note: The NASA Task Load Index was used. This article may be obtained online without charge.

...

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