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NASA Spaceline Current Awareness List #897 1 May 2020 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, May 1, 2020

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

 

 

Papers deriving from NASA support:

 

1

Urbaniak C, Lorenzi H, Thissen J, Jaing C, Crucian B, Sams C, Pierson D, Venkateswaran K, Mehta S.

The influence of spaceflight on the astronaut salivary microbiome and the search for a microbiome biomarker for viral reactivation.

Microbiome. 2020 Apr 20;8(1):56.

https://www.ncbi.nlm.nih.gov/pubmed/32312311

PIs: H. Lorenzi; C. Jaing; C. Sams; K. Venkateswaran; C. Urbaniak, NASA Postdoctoral Program Fellowship

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: 10.465

Funding: "Part of the research described in this publication was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with NASA. We would like to thank all the astronauts who participated in this study which is funded by the NASA Human Research Program SMO-015 (CS) and NNX12AB02G (HL). LLNL research was funded by a 2014 Space Biology NNH14ZTT002N grant no. 80NSSC18K0113 award to CJ. This research was also funded by a 2012 Space Biology NNH12ZTT001N grant no. 19-12829-26 under Task Order NNN13D111T award to KV. This grant and NASA Postdoctoral Program sponsored by Space Biology funded the fellowship for CU."

 

2

Jain V, Ploutz-Snyder R, Young M, Charvat JM, Wotring VE.

Potential venous thromboembolism risk in female astronauts.

Aerosp Med Hum Perform. 2020 May 1;91(5):432-9.

https://www.ncbi.nlm.nih.gov/pubmed/32327017

Note: Space Shuttle and ISS results.

Journal Impact Factor: 0.889

Funding: No funding cited. M. Young and J.M. Charvat are affiliated with NASA Johnson Space Center.

 

3

Smith RC, Cramer MS, Mitchell PJ, Lucchesi J, Ortega AM, Livingston EW, Ballard D, Zhang L, Hanson J, Barton K, Berens S, Credille KM, Bateman TA, Ferguson VL, Ma YL, Stodieck LS. 

Inhibition of myostatin prevents microgravity-induced loss of skeletal muscle mass and strength.

PLoS One. 2020 Apr 21;15(4):e0230818.

https://www.ncbi.nlm.nih.gov/pubmed/32315311

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: 2.776

Funding: "Funding for this work was provided in part to VLF, TAB, and LSS by the Center for the Advancement of Science in Space or CASIS (GA-2016-239, T/O #003)....Additional support was provided by NASA for the development of the anesthesia/recovery system and anesthesia protocol used in the study (NNJ10GA25A). Development and provision of the ISS Bone Densitometer was supported by CASIS and NASA contracts NNJ13GA01C and NNJ10GA35C to Techshot, Inc. Eli Lilly and Company and TechShot Inc. provided support in the form of salaries for authors [RCS, MSC, PJM, JL, DB, LZ, JH, SB, KMC, YLM, KB], but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript."

 

4

Simpson RJ, Katsanis E.

The immunological case for staying active during the COVID-19 pandemic.

Brain Behav Immun. 2020 Apr 18. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32311497

PI: R.J. Simpson

Note: ISS results are discussed. This article may be obtained online without charge.

Journal Impact Factor: 6.17

Funding: "This work was supported by NASA grant 80NSSC19K105."

 

5

McIntyre ABR, Gokhale NS, Cerchietti L, Jaffrey SR, Horner SM, Mason CE.

Limits in the detection of m6A changes using MeRIP/m6A-seq.

Sci Rep. 2020 Apr 20;10(1):6590.

https://www.ncbi.nlm.nih.gov/pubmed/32313079

PI: C.E. Mason

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.011

Funding: "We are grateful for funding from the Starr Cancer Consortium (I9-A9-071), the Bert L and N. Kuggie Vallee Foundation, the WorldQuant Foundation, The Pershing Square Sohn Cancer Research Alliance, NASA (NNX14AH50G), the National Institutes of Health (R01AI125416, R21AI129851, R01MH117406), the Leukemia and Lymphoma Society (LLS) grants (LLS 9238-16, Mak, LLS-MCL-982, Chen-Kiang), the Burroughs Wellcome Fund (S.M.H.), the Natural Sciences and Engineering Research Council of Canada (A.B.R.M. PGS-D funding), and the American Heart Association (N.S.G. Pre-doctoral Fellowship, 17PRE33670017)."

 

6

Chappell LJ, Elgart SR, Milder CM, Semones EJ.

Assessing nonlinearity in Harderian gland tumor induction using three combined HZE-irradiated mouse datasets.

Radiat Res. 2020 Apr 24. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32330076

Journal Impact Factor: 2.530

Funding: No funding cited. L.J. Chappell, C.M. Milder, and E.J. Semones are affiliated with NASA Johnson Space Center.

 

7

Nasrini J, Hermosillo E, Dinges DF, Moore TM, Gur RC, Basner M.

Cognitive performance during confinement and sleep restriction in NASA's Human Exploration Research Analog (HERA).

Front Physiol. 2020 Apr 28;11:394.

https://www.frontiersin.org/article/10.3389/fphys.2020.00394

PI: M. Basner

Note: Results are from the Human Exploration and Research (HERA) project. This article may be obtained online without charge.

Journal Impact Factor: 3.201

Funding: "Supported by NASA through NNX14AH98G and the National Space Biomedical Research Institute through NASA NCC 9-58."

 

8

Tang YQ, Lee SA, Rahman M, Vanapalli SA, Lu H, Schafer WR.

Ankyrin is an intracellular tether for TMC mechanotransduction channels.

Neuron. 2020 Apr 11. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32325031

PI: S.A. Vanapalli

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.776

Funding: "This work was funded by Medical Research Council grant MC-A023-5PB91 and Wellcome Trust grant WT103784MA to W.R.S., NIH grant 1R21DC015652 to H.L. and W.R.S., NIH grant R01NS096581 to H.L., and grants from NASA (NNX15AL16G) and the Cancer Prevention and Research Institute of Texas (RP160806) to S.A.V."

 

9

Kusuma P, Pattison PM, Bugbee B.

From physics to fixtures to food: Current and potential LED efficacy.

Hortic Res. 2020 Mar 30;7:56.

https://www.ncbi.nlm.nih.gov/pubmed/32257242

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.640

Funding: "This work was supported by the Utah Agricultural Experiment Station, Utah State University, journal paper number 9260; the USDA-NIFA-SCRI award 2018-51181-28365 (LAMP Project); the NASA-CUBES award number NNX17AJ31G, and the Department of Energy through the Energy Efficiency and Renewable Energy Buildings Technologies Office Lighting R&D Program under contract #DEFE0025912 at the National Energy Technology Laboratory on the Mission Execution and Strategic Analysis contract with KeyLogic."

______________________________________________________

 

 

Other papers of interest:

 

1

Bringoux L, Macaluso T, Sainton P, Chomienne L, Buloup  F, Mouchnino L, Simoneau M, Blouin J.

Double-step paradigm in microgravity: Preservation of sensorimotor flexibility in altered gravitational force field.

Front Physiol. 2020 Apr 24;11:377.

https://www.frontiersin.org/article/10.3389/fphys.2020.00377

Note: Parabolic flight results. This article may be obtained online without charge.

 

2

Koryak YA.

Isokinetic force and work capacity after long-duration space station Mir and short-term International Space Station missions.

Aerosp Med Hum Perform. 2020 May 1;91(5):422-31.

https://www.ncbi.nlm.nih.gov/pubmed/32327016

Note: Mir and ISS results.

 

3

Vasilieva NA, Tchabovsky AV.

Early predictors of female lifetime reproductive success in a solitary hibernator: Evidence for "silver spoon" effect.

Oecologia. 2020 Apr 21. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32318852

 

4

Lin T, Du J, Liu L, Wu Z, Kong X, Liu Y, Cai Y.

Treatment with minocycline suppresses microglia activation and reverses neural stem cell loss after simulated microgravity.

Biomed Res Int. 2020 Apr 25;2020:7348745.

https://www.hindawi.com/journals/bmri/2020/7348745/

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

5

Belova SP, Mochalova EP, Kostrominova TY, Shenkman BS, Nemirovskaya TL.

P38α-MAPK signaling inhibition attenuates soleus atrophy during early stages of muscle unloading.

Int J Mol Sci. 2020 Apr 15;21(8):2756.

https://www.ncbi.nlm.nih.gov/pubmed/32326654

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

6

Owen PJ, Ambrecht G, Bansmann M, Zange J, Pohle-Fröhlich R, Felsenberg D, Belavý DL.

Whey protein supplementation with vibration exercise ameliorates lumbar paraspinal muscle atrophy in prolonged bed-rest.

J Appl Physiol (1985). 2020 Apr 23. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32324477

Note: Bed rest study.

 

7

McDonnell AC, Eiken O, Mekjavic IB, Žlak N, Drobnič M.

The influence of a sustained 10-day hypoxic bed rest on cartilage biomarkers and subchondral bone in females: The FemHab study.

Physiol Rep. 2020 Apr;8(8):e14413.

https://www.ncbi.nlm.nih.gov/pubmed/32333524

Note: Bed rest study. This article may be obtained online without charge.

 

8

Cortesão M, de Haas A, Unterbusch R, Fujimori A, Schütze T, Meyer V, Moeller R.

Aspergillus niger spores are highly resistant to space radiation.

Front Microbiol. 2020 Apr 3;11:560.

https://www.ncbi.nlm.nih.gov/pubmed/32318041

Note: This article may be obtained online without charge.

 

9

Gleason JD, Oishi M, Simkulet M, Tuzikas A, Hanifin JP, Brainard GC, Brueck SRJ, Karlicek RF Jr, Brown LK.

Smart lighting clinical testbed pilot study on circadian phase advancement.

IEEE J Transl Eng Health Med. 2019 Aug 30;7:3200110.

https://www.ncbi.nlm.nih.gov/pubmed/32309057      

Note: This article may be obtained online without charge.

 

10

Fowler CG, Dallapiazza M, Hadsell KT.

Vestibular function and motion sickness susceptibility: Videonystagmographic evidence from oculomotor and caloric tests.

Am J Audiol. 2020 Apr 22. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32320620

 

11

Jennings RT, Charles JB.

Need more chimp flights: Medical drama and presidential decision-making in Project Mercury.

Aerosp Med Hum Perform. 2020 May 1;91(5):462-4.

https://www.ncbi.nlm.nih.gov/pubmed/32327025

Note: The authors recount events and decisions around the number of chimp flights leading up to human flight in Project Mercury.

 

12

Kreykes AJ, Petersen EH, Lowry CL.

Expanding knowledge and exposure to aerospace medicine by creating a medical student curriculum.

Aerosp Med Hum Perform. 2020 May 1;91(5):448-52.

https://www.ncbi.nlm.nih.gov/pubmed/32327019

 

13

Criscuolo F, Sueur C, Bergouignan A.

Human adaptation to deep space environment: An evolutionary perspective of the foreseen interplanetary exploration.

Front Public Health. 2020 Apr 24;8:119.

https://www.frontiersin.org/article/10.3389/fpubh.2020.00119

Note: This article may be obtained online without charge.

 

14

Dinneny JR.

Mechanobiology: Plant cells face pressure from neighbors.

Curr Biol. 2020 Apr 20;30(8):R344-R346.

https://www.ncbi.nlm.nih.gov/pubmed/32315631

 

15

Medina FJ.

Growing plants in human space exploration enterprises.

Acta Futura. 2020 Apr 10;12:151-63.

https://zenodo.org/record/3747367#.XqhGp5kpBPY

Note: This article may be obtained online without charge.

 

16

Rath M, Dümmer M, Galland P, Forreiter C.

A gravitropic stimulus alters the distribution of EHB1, a negative effector of root gravitropism in Arabidopsis.

Plant Direct. 2020 Apr 20;4(4):e00215.

https://www.ncbi.nlm.nih.gov/pubmed/32318652

Note: This article may be obtained online without charge.

 

17

Wang X, Yu R, Wang J, Lin Z, Han X, Deng Z, Fan L, He H, Deng XW, Chen H.

The asymmetric expression of SAUR genes mediated by ARF7/19 promotes the gravitropism and phototropism of plant hypocotyls.

Cell Rep. 2020 Apr 21;31(3):107529.

https://www.ncbi.nlm.nih.gov/pubmed/32320660

Note: This article may be obtained online without charge.

 

18

Cao S, Han TY, Li Q, Peng L, Zhao C, Tang Y, Xu J.

Tunable spectrum resemblance of LED lights for improving the photosynthetic action of Chinese cabbages.

Life Sci Space Res. 2020 Apr 28. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552420300213

 

19

Amalfitano S, Levantesi C, Copetti D, Stefani F, Locantore I, Guarnieri V, Lobascio C, Bersani F, Giacosa D, Detsis E, Rossetti S.

Water and microbial monitoring technologies towards the near future space exploration.

Water Res. 2020 Jun;177:115787. Epub 2020 Apr 11.

https://www.ncbi.nlm.nih.gov/pubmed/32315899

 

20

Ding Y, Cao Y, Duffy VG, Wang Y, Xuefeng Z.

Measurement and identification of mental workload during simulated computer tasks with multimodal methods and machine learning.

Ergonomics. 2020 Apr 24. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32330080

Note: The NASA Task Load Index was used.

// end //

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