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NASA Spaceline Current Awareness List #896 24 April 2020 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, April 24, 2020

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

 

Papers deriving from NASA support:

 

1

Roma PG, Beckner ME, Mehta SK, Nindl BC, Crucian BE.

Salivary bioscience in military, space, and operational research.

In: Granger DA, Taylor MK, eds. Salivary Bioscience: Foundations of Interdisciplinary Saliva Research and Applications. Cham: Springer, 2020. p. 585-610.

https://link.springer.com/chapter/10.1007%2F978-3-030-35784-9_24

PI: D.F. Dinges

Journal Impact Factor: Not applicable to this publication

Funding: "PGR and SKM are supported by KBR's Human Health & Performance Contract NNJ15HK11B through the National Aeronautics and Space Administration. MEB, BCN, and PGR are supported in part by United States Army grant W81XWH-17-2-0070 (B. C. Nindl, PI) and NASA Human Research Program grant NNX15AK76A (D. F. Dinges, PI/PD). BEC is supported by the National Aeronautics and Space Administration, Human Health and Performance Directorate."

 

2

Caulfield KA, Lopez JW, Cox CE, Roberts DR, McTeague LM.

A new, open-source 3D-printed transcranial magnetic stimulation (TMS) coil tracker holder for double blind, sham-controlled neuronavigation studies.

Brain Stimul. 2020 May-Jun;13(3):600-2.

https://www.ncbi.nlm.nih.gov/pubmed/32289684

PI: D.R. Roberts

Note: This article may be obtained online without charge.

Journal Impact Factor: 6.919

Funding: "This study was supported by the Translational Research Institute for Space Health through NASA, NNX16AO69A."

 

3

Clément GR, Boyle RD, George KA, Nelson GA, Reschke MF, Williams TJ, Paloski WH.

Challenges to the central nervous system during human spaceflight missions to Mars.

J Neurophysiol. 2020 Apr 15. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/32292116

Journal Impact Factor: 2.614

Funding: No funding cited. G.R. Clément, R.D. Boyle, K.A. George, M.F. Reschke, T.J. Williams, and W.H. Paloski are affiliated with NASA.

 

4

Steczina S, Tahimic CGT, Pendleton M, M'Saad O, Lowe M, Alwood JS, Halloran BP, Globus RK, Schreurs AS.

Dietary countermeasure mitigates simulated spaceflight-induced osteopenia in mice.

Sci Rep. 2020 Apr 16;10(1):6484.

https://www.ncbi.nlm.nih.gov/pubmed/32300161

PI: A.S. Schreurs

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.011

Funding: "This work was supported by a NASA Human Research Program (HRP) Human Health Countermeasure (HHC) omnibus (15–15Omni2–0039, PI: Ann-Sofie Schreurs). Funding was also provided through NASA Space Biology with NASA Post-Doctoral Program (NPP) and Space Life Science Training Program (SLSTP) support."

 

5

Marchant A, Ball N, Witchalls J, Waddington G, Mulavara AP, Bloomberg JJ.

The effect of acute body unloading on somatosensory performance, motor activation, and visuomotor tasks.

Front Physiol. 2020 Apr 17;11:318.

https://www.frontiersin.org/articles/10.3389/fphys.2020.00318

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.201

Funding: No funding cited. J.J. Bloomberg and A.P. Mulavara are affiliated with NASA Johnson Space Center.

 

6

Taylor Z.

A study of space bathroom design.

Acta Astronaut. 2020 Apr 21. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0094576520302319

Journal Impact Factor: 2.482

Funding: No funding cited. Z. Taylor is affiliated with NASA Johnson Space Center.

 

7

Massaro Tieze S, Liddell LC, Santa Maria SR, Bhattacharya S.

BioSentinel: A biological CubeSat for deep space exploration.

Astrobiology. 2020 Apr 13. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32282239

Note: This article may be obtained online without charge.

Journal impact Factor: 3.768

Funding: "This work was supported by NASA's Advanced Exploration Systems Division in the Human Exploration and Operations Mission Directorate."

______________________________________________________

 

 

Other paper of interest:

 

1

Angelaki DE, Ng J, Abrego AM, Cham HX, Asprodini EK, Dickman JD, Laurens J.

A gravity-based three-dimensional compass in the mouse brain.

Nat Commun. 2020 Apr 15;11(1):1855.

https://www.ncbi.nlm.nih.gov/pubmed/32296057

Note: A tilt table and multi-axis rotator were used. This article may be obtained online without charge.

 

2

Bevelacqua JJ, Welsh J, Mortazavi SMJ.

Comment on "Salivary antimicrobial proteins and stress biomarkers are elevated during a 6-month mission to the International Space Station."

J Appl Physiol (1985). 2020 Apr 1;128(4):1088-9.

https://www.ncbi.nlm.nih.gov/pubmed/32293920

Note: The authors comment on: Agha NH, Baker FL, Kunz HE, Spielmann G, Mylabathula PL, Rooney BV, Mehta SK, Pierson DL, Laughlin MS, Markofski MM, Crucian BE, Simpson RJ. Salivary antimicrobial proteins and stress biomarkers are elevated during a 6-month mission to the International Space Station. J Appl Physiol (1985) 128: 264–275, 2020. https://www.ncbi.nlm.nih.gov/pubmed/31751178, which appeared in SPACELINE Current Awareness List #876 on 29 Nov 2019. This article may be obtained online without charge.

 

3

Yim J, Cho SW, Kim B, Park S, Han YH, Seo SW.

Transcriptional profiling of the probiotic Escherichia coli Nissle 1917 strain under simulated microgravity.

Int J Mol Sci. 2020 Apr 11;21:8.

https://www.ncbi.nlm.nih.gov/pubmed/32290466

Note: A clinostat was used. This article may be obtained online without charge.

 

4

Flores K, Siques P, Brito J, Ordenes S, Arriaza K, Pena E, León-Velarde F, López R, López de Pablo ÁL, Arribas S.

Lower body weight in rats under hypobaric hypoxia exposure would lead to reduced right ventricular hypertrophy and increased AMPK activation.

Front Physiol. 2020 Apr 20;11:342.

https://www.frontiersin.org/article/10.3389/fphys.2020.00342

Note: This article may be obtained online without charge.

 

5

Zhang R, Jiang M, Zhang J, Qiu Y, Li D, Li S, Liu J, Liu C, Fang Z, Cao F.

Regulation of the cerebrovascular smooth muscle cell phenotype by mitochondrial oxidative injury and endoplasmic reticulum stress in simulated microgravity rats via the PERK-eIF2α-ATF4-CHOP pathway.

Biochim Biophys Acta Mol Basis Dis. 2020 Apr 15. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32304741

Note: Hindlimb unloading study.

 

6

Pollock RD, Gates SD, Storey JA, Radcliffe JJ, Stevenson AT.

Indices of acceleration atelectasis and the effect of hypergravity duration on its development.

Exp Physiol. 2020 Apr 13. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32281162

Note: Centrifugation was used.

 

7

Fernandez-Gonzalo R, Tesch PA, Lundberg TR, Alkner BA, Rullman E, Gustafsson T.

Three months of bed rest induce a residual transcriptomic signature resilient to resistance exercise countermeasures.

FASEB J. 2020 Apr 15. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32293758

Note: Bed rest study. This article may be obtained online without charge.

 

8

Nay K, Martin D, Orfila L, Saligaut D, Martin B, Horeau M, Cavey T, Kenawi M, Island ML, Ropert M, Loréal O, Koechlin-Ramonatxo C, Derbré F.

Intermittent reloading does not prevent iron availability decrease and hepcidin upregulation caused by hindlimb unloading.

Exp Physiol. 2020 Apr 13. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32281155

Note: Hindlimb unloading study.

 

9

Vikne H, Strøm V, Hugo Pripp A, Gjøvaag T.

Human skeletal muscle fiber type percentage and area after reduced muscle use. A systematic review and meta-analysis.

Scand J Med Sci Sports. 2020 Apr 13. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/32281690

Note: From the abstract: "The reduced muscle activity models were detraining, leg unloading and bed rest."  This article may be obtained online without charge.

 

10

Poirier Y, Belley MD, Dewhirst MW, Yoshizumi TT, Down JD.

Transitioning from gamma rays to X-rays for comparable biomedical research irradiations: Energy matters.

Radiat Res. 2020 Apr 21. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32315248

 

11

Basu D, Shoots JM, Haswell ES.

Interactions between the N- and C- termini of mechanosensitive ion channel AtMSL10 are consistent with a three-step mechanism for activation.

J Exp Bot. 2020 Apr 13. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32280992

 

12

Fahrion J, Fink C, Zabel P, Schubert D, Mysara M, Van Houdt R, Eikmanns B, Beblo-Vranesevic K, Rettberg P.

Microbial monitoring in the EDEN ISS greenhouse, a mobile test facility in Antarctica.

Front Microbiol. 2020 Mar 3;11:525.

https://www.ncbi.nlm.nih.gov/pubmed/32296408

Note: This article may be obtained online without charge.

 

13

Coleman ML, Bause GS.

No monkeying around: An anesthesiologist at the heart of NASA and Project Mercury.

Anesthesiology. 2020 May;132(5):1033.

https://www.ncbi.nlm.nih.gov/pubmed/32287161

Note: This is a brief note about Dr. Cloid Green, the NASA project officer charged with development of a life support system for Project Mercury primate flights.

 

14

Wein AJ.

Re: How do astronauts urinate? The history of innovations enabling voiding in the void.

J Urol. 2020 Apr 15. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32293963

Note: The author comments on: Maciolek KA, Best SL. How do astronauts urinate? The history of innovations enabling voiding in the void. Urology. 2019 Jun;128:8-13. Epub 2019 Feb 26.https://www.ncbi.nlm.nih.gov/pubmed/30822481, which appeared in SPACELINE Current Awareness List #840, 15 Mar 2019.

 

15

Harris K.

Where no one can hear you scream: Regulating the commercial space industry to ensure human safety.

Health Matrix. 2020;30(1):375-405.

https://scholarlycommons.law.case.edu/healthmatrix/vol30/iss1/9

Note: This article may be obtained online without charge.

 

16

Alyan E, Saad NM, Kamel N.

Effects of workstation type on mental stress: fNIRS study.

Hum Factors. 2020 Apr 14. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32286888

Note: The NASA Task Load Index was used.

// end //

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