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NASA Spaceline Current Awareness List #887 21 February 2020 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, February 21, 2020

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website athttps://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

  

Papers deriving from NASA support:

 

1

Choi SY, Saravia-Butler A, Shirazi-Fard Y, Leveson-Gower D, Stodieck LS, Cadena SM, Beegle J, Solis S, Ronca A, Globus RK.

Validation of a new rodent experimental system to investigate consequences of long duration space habitation.

Sci Rep. 2020 Feb 11;10(1):2336.

https://www.ncbi.nlm.nih.gov/pubmed/32047211

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: 4.011

Funding: No funding cited. S.Y. Choi, Y. Shirazi-Fard, D. Leveson-Gower, J. Beegle, A. Ronca, and R.K. Globus are affiliated with NASA Ames Research Center.

 

2

O'Rourke A, Lee MD, Nierman WC, Everroad RC, Dupont CL.

Genomic and phenotypic characterization of Burkholderia isolates from the potable water system of the International Space Station.

PLoS One. 2020 Feb 20;15(2):e0227152. 

https://www.ncbi.nlm.nih.gov/pubmed/32074104

PIs: A. O'Rouke and M.D. Lee, NASA Postdoctoral Fellowships

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: 2.776

Funding: "Aubrie O’Rourke was funded by NASA Space Biology under grant 80NSSC17K0035. Michael D. Lee was funded by NASA Space Biology under grant NNH16ZTT001N-MOBE. Chris L. Dupont was funded by the NASA Astrobiology Institute Alternative Earths."

 

3

Padgen MR, Chinn TN, Friedericks CR, Lera MP, Chin M, Parra MP, Piccini ME, Ricco AJ, Spremo SM.

The EcAMSat fluidic system to study antibiotic resistance in low Earth orbit: Development and lessons learned from space flight.

Acta Astronaut. 2020 Feb 19. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S009457652030093X

Note: Design and assembly of the E. coli AntiMicrobial Satellite (EcAMSat) are discussed.

Journal Impact Factor: 2.482

Funding: "This research was supported by NASA's Space Life and Physical Sciences Research Division, Human Exploration and Operations Mission Directorate, at NASA/ARC."

 

4

Ortega SB, Torres VO, Latchney SE, Whoolery CW, Noorbhai IZ, Poinsatte K, Selvaraj UM, Benson MA, Meeuwissen AJM, Plautz EJ, Kong X, Ramirez DM, Ajay AD, Meeks JP, Goldberg MP, Monson NL, Eisch AJ, Stowe AM. 

B cells migrate into remote brain areas and support neurogenesis and functional recovery after focal stroke in mice.

Proc Natl Acad Sci U S A. 2020 Feb 12. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32051245

PI: A.J. Eisch

Note: This article may be obtained online without charge.

Journal Impact Factor: 9.580

Funding: "This study was funded by grants to A.M.S. from the American Heart Association (14SDG18410020), NIH/NINDS (NS088555), the Dana Foundation David Mahoney Neuroimaging Program, and The Haggerty Center for Brain Injury and Repair (UTSW); to S.B.O. from the American Heart Association (14POST20480373) and NIH/NINDS (3R01NS088555-03S1); to V.O.T. from the NIH/NIAID (5T32AI005284-40) and NIH/NINDS (3R01NS088555-02S1); to U.M.S. from the American Heart Association (17PRE33660147); and to A.J.E. from the NIH (DA023701, DA023555, MH107945) and the US National Aeronautics and Space Administration (NNX15AE09G). S.E.L. and C.W.W. were funded by an NIH institutional training grant (DA007290, Basic Science Training Program in the Drug Abuse Research, Principal Investigator A.J.E.). The UT Southwestern Whole Brain Microscopy Facility and the Neuro-Models Facility are supported by the Texas Institute for Brain Injury and Repair (TIBIR)."

 

5

Baker FL, Bigley AB, Agha NH, Pedlar CR, O'Connor DP, Bond RA, Bollard CM, Katsanis E, Simpson RJ.

Systemic β-adrenergic receptor activation augments the ex vivo expansion and anti-tumor activity of Vγ9Vδ2 T-cells.

Front Immunol. 2020 Jan 24;10:3082.

https://www.ncbi.nlm.nih.gov/pubmed/32038628

PI: R.J. Simpson

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.716

Funding: "This work was supported by NASA Grants NNX12AB48G, NNX16AB29G, and NNX16AG02G and NIH Grant R21 CA197527-01A1."

 

6

McDonald JT, Stainforth R, Miller J, Cahill T, da Silveira WA, Rathi KS, Hardiman G, Taylor D, Costes SV, Chauhan V, Meller R, Beheshti A.

NASA GeneLab platform utilized for biological response to space radiation in animal models.

Cancers (Basel). 2020 Feb 7;12(2):E381.

https://www.ncbi.nlm.nih.gov/pubmed/32045996

Note: GeneLab is available at: https://genelab.nasa.gov/. This article may be obtained online without charge.

Journal Impact Factor: 6.162

Funding: "Research funding was provided by the GeneLab Project at NASA Ames Research Center, through NASA's Space Biology Program in the Division of Space Life and Physical Sciences Research and Applications (SLPSRA)."

 

7

Suman S, Shuryak I, Kallakury B, Brenner DJ, Fornace AJ Jr, Johnson MD, Datta K.

Protons show greater relative biological effectiveness for mammary tumorigenesis with higher ERα and HER2 positive tumors relative to γ-rays in APCMin/+ mice.

Int J Radiat Oncol Biol Phys. 2020 Feb 6. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32036005

PIs: K. Datta; A.J. Fornace Jr/D.J. Brenner/K. Datta/NSCOR

Journal Impact Factor: 6.203

Funding: "This study is supported by NASA Grant# NNX13AD58G and NNX15AI21G."

______________________________________________________

 

 

Other papers of interest:

 

1

Cai, ZY, Wang WY, Lin JD, Wu CM.

Effects of whole body vibration training combined with blood flow restriction on muscle adaptation.

Eur J Sport Sci. 2020 Feb 13. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32050853

 

2

Thalacker-Mercer A, Riddle E, Barre L.

Protein and amino acids for skeletal muscle health in aging.

Adv Food Nutr Res. 2020;91:29-64.

https://www.ncbi.nlm.nih.gov/pubmed/32035599

 

3

Liu J, Wang J, Guo Y.

Effect of collagen peptide, alone and in combination with calcium citrate, on bone loss in tail-suspended rats.

Molecules. 2020 Feb 12;25(4):E782.

https://www.ncbi.nlm.nih.gov/pubmed/32059436

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

4

Mohammad Rahimi GR, Smart NA, Liang MTC, Bijeh N, Albanaqi AL, Fathi M, Niyazi A, Mohammad Rahimi N.

The impact of different modes of exercise training on bone mineral density in older postmenopausal women: A systematic review and meta-analysis research.

Calcif Tissue Int. 2020 Feb 13. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/32055889

 

5

Nakajima K, Matsunaga S, Morioka T, Nakano T, Abe S, Furuya Y, Yajima Y.

Effects of unloading by tail suspension on biological apatite crystallite alignment in mouse femur.

Dent Mater J. 2020 Feb 7. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32037388

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

6

Riquelme MA, Cardenas ER, Xu H, Jiang JX.

The role of connexin channels in the response of mechanical loading and unloading of bone.

Int J Mol Sci. 2020 Feb 9;21(3):E1146. Review.

https://www.ncbi.nlm.nih.gov/pubmed/32050469

Note: Mouse models for hindlimb unloading are discussed. This article may be obtained online without charge.

 

7

Robling AG, Bonewald LF.

The osteocyte: New insights.

Annu Rev Physiol. 2020 Feb 10;82:485-506. Review.

https://www.ncbi.nlm.nih.gov/pubmed/32040934

 

8

Yang BC, Kuang MJ, Kang JY, Zhao J, Ma JX, Ma XL.

Human umbilical cord mesenchymal stem cell-derived exosomes act via the miR-1263/Mob1/Hippo signaling pathway to prevent apoptosis in disuse osteoporosis.

Biochem Biophys Res Commun. 2020 Feb 10. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32057365

Note: Hindlimb unloading study.

 

9

Yi X, Wu L, Liu J, Qin YX, Li B, Zhou Q.

Low-intensity pulsed ultrasound protects subchondral bone in rabbit temporomandibular joint osteoarthritis by suppressing TGF-β1/Smad3 pathway.

J Orthop Res. 2020 Feb 15. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32060941

 

10

Farris MK, Helis CA, Hughes RT, LeCompte MC, Borg AM, Nieto K, Munley MT, Willey JS.

Bench to bedside: Animal models of radiation induced musculoskeletal toxicity.

Cancers (Basel). 2020 Feb 12;12(2):E427. Review.

https://www.ncbi.nlm.nih.gov/pubmed/32059447

Note: This article may be obtained online without charge.

 

11

Gronberg MP, Tailor RC, Smith SA, Kry SF, Followill DS, Stojadinovic S, Niedzielski JS, Lindsay PE, Krishnan S, Aguirre F, Fujimoto TN, Taniguchi CM, Howell RM.

A mail audit independent peer review system for dosimetry verification of a small animal irradiator.

Radiat Res. 2020 Feb 18. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32068498

 

12

Laurenzi S, de Zanet G, Santonicola MG.

Numerical investigation of radiation shielding properties of polyethylene-based nanocomposite materials in different space environments.

Acta Astronaut. 2020 Feb 18. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0094576520300898

 

13

Li Y, Cucinotta FA.

Mathematical model of ATM activation and chromatin relaxation by ionizing radiation.

Int J Mol Sci. 2020 Feb 12;21(4):E1214.

https://www.ncbi.nlm.nih.gov/pubmed/32059363

Note: This article may be obtained online without charge.

 

14

Porras DC, Zeilig G, Doniger GM, Bahat Y, Inzelberg R, Plotnik M.

Seeing gravity: Gait adaptations to visual and physical inclines  A virtual reality study.

Front Neurosci. 2020 Jan 24;13:1308.

https://www.ncbi.nlm.nih.gov/pubmed/32038123

Note: This article may be obtained online without charge.

 

15

Bronstein AM, Golding JF, Gresty MA.

Visual vertigo, motion sickness, and disorientation in vehicles.

Semin Neurol. 2020 Feb 11. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32045940

 

16

Keywan A, Badarna H, Jahn K, Wuehr M.

No evidence for after-effects of noisy galvanic vestibular stimulation on motion perception.

Sci Rep. 2020 Feb 13;10(1):2545.

https://www.ncbi.nlm.nih.gov/pubmed/32054910

Note: This article may be obtained online without charge.

 

17

Emenecker RJ, Strader LC.

Auxin-abscisic acid interactions in plant growth and development.

Biomolecules. 2020 Feb 12;10(2):E281. Review.

https://www.ncbi.nlm.nih.gov/pubmed/32059519

Note: This article may be obtained online without charge.

 

18

Li Y, Wang Y, Tan S, Li Z, Yuan Z, Glanc M, Domjan D, Wang K, Xuan W, Guo Y, Gong Z, Friml J, Zhang J.

Root growth adaptation is mediated by PYLs ABA receptor-PP2A protein phosphatase complex.

Adv Sci (Weinh). 2020 Feb;7(3):1901455.

https://www.ncbi.nlm.nih.gov/pubmed/32042554

Note: This article may be obtained online without charge.

 

19

Garot O, Rössler J, Pfarr J, Ganter MT, Spahn DR, Nöthiger CB, Tscholl DW.

Avatar-based versus conventional vital sign display in a central monitor for monitoring multiple patients: A multicenter computer-based laboratory study.

BMC Med Inform Decis Mak. 2020 Feb 10;20(1):26. https://www.ncbi.nlm.nih.gov/pubmed/32041584

Note: The NASA Task Load Index was used. This article may be obtained online without charge.

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