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NASA Spaceline Current Awareness List #881 10 January 2020 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, January 10, 2020

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

 

Papers deriving from NASA support:

 

1

Auñón-Chancellor SM, Pattarini JM, Moll S, Sargsyan A.

Venous thrombosis during spaceflight.

N Engl J Med. 2020 Jan 2;382(1):89-90.

https://www.ncbi.nlm.nih.gov/pubmed/31893522

Note: ISS results.

Journal Impact Factor: 70.670

Funding: No funding cited. S.M. Auñón-Chancellor, J.M. Pattarini, and A. Sargsyan are affiliated with NASA Johnson Space Center.

 

2

Iosim S, MacKay M, Westover C, Mason CE.

Translating current biomedical therapies for long duration, deep space missions.

Precis Clin Med. 2019 Dec;2(4):259-69.

https://www.ncbi.nlm.nih.gov/pubmed/31886035

PI: C.E. Mason

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "We would like to thank the Epigenomics Core Facility at Weill Cornell Medicine, the Scientific Computing Unit (SCU), as well as the Starr Cancer Consortium (I9-A9–071) and funding from the Irma T. Hirschl and Monique Weill-Caulier Charitable Trusts, Bert L and N Kuggie Vallee Foundation, the WorldQuant Foundation, the Pershing Square Sohn Cancer Research Alliance, NASA (Grants No. NNX14AH50G, NNX17AB26G), the National Institutes of Health (Grants No. R25EB020393, R01NS076465, R01AI125416, R01ES021006, 1R21AI129851, P01HD067244, 1R01MH117406), TRISH (Grants No. NNX16AO69A:0107, NNX16AO69A:0061), the Bill and Melinda Gates Foundation (Grants No. OPP1151054), the Leukemia and Lymphoma Society (LLS) grants (No. LLS 9238–16, Mak, No. LLS-MCL-982, Chen-Kiang) and the NSF (Grants No. 1840275), the Alfred P. Sloan Foundation (Grants No. G-2015-13964)."

 

3

Nicholson WL, Ricco AJ.

Nanosatellites for biology in space: In situ measurement of Bacillus subtilis spore germination and growth after 6 months in low Earth orbit on the O/OREOS Mission.

Life (Basel). 2019 Dec 29;10(1):E1.

https://www.ncbi.nlm.nih.gov/pubmed/31905771

Note: O/OREOS mission results. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This research was funded by NASA grant numbers NNA06CB58G and NNX10AV22G to W.L.N. and by NASA-IPA contract NNA19OB01P to A.J.R."

 

4

Ung L, Bispo PJM, Bryan NC, Andre C, Chodosh J, Gilmore MS.

The best of all worlds: Streptococcus pneumoniae conjunctivitis through the lens of community ecology and microbial biogeography.

Microorganisms. 2019 Dec 25;8(1):E46.

https://www.ncbi.nlm.nih.gov/pubmed/31881682

PI: N. Bryan, Space Biology Postdoctoral Fellowship

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.167

Funding: "This research was supported in part by EY024285 and AI083214 from the National Institutes of Health, and an unrestricted grant to the Department of Ophthalmology, Harvard Medical school, from Research to Prevent Blindness, NY, NY. L.U. was also supported by the Dozoretz Family Foundation. N.C.B. was supported by a NASA Space Biology Fellowship, award 80NSSC17K0688."

 

5

Khokhlova TD, Schade GR, Wang YN, Buravkov SV, Chernikov VP, Simon JC, Starr F, Maxwell AD, Bailey MR, Kreider W, Khokhlova VA.

Pilot in vivo studies on transcutaneous boiling histotripsy in porcine liver and kidney.

Sci Rep. 2019 Dec 27;9(1):20176.

https://www.ncbi.nlm.nih.gov/pubmed/31882870

PIs: V.A. Khokhlova; M.R. Bailey; and J.C. Simon, NSBRI Postdoctoral Fellowship Program

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.011

Funding: "This work was supported by NIH R01 EB7643, R01 GM122859, R21CA219793, NSBRI through NASA NCC 9-58, Urology Care Foundation, and RFBR 17-54-33034."

 

6

Mellor LF, Nordberg RC, Huebner P, Mohiti-Asli M, Taylor MA, Efird W, Oxford JT, Spang JT, Shirwaiker RA, Loboa EG.

Investigation of multiphasic 3D-bioplotted scaffolds for site-specific chondrogenic and osteogenic differentiation of human adipose-derived stem cells for osteochondral tissue engineering applications.

J Biomed Mater Res B Appl Biomater. 2019 Dec 27. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31880408

PI: L.F. Mellor

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.221

Funding: "This work was supported in part by the OREF Career Development Award/National Stem Cell Foundation # 15-059 (J.S., E.G.L., R.A.S.). National Space Biomedical Research Institute through NASA NCC9-58 (L.F.M.), NIH/NIBIB 1R03EB008790 (E.G.L.), NIH/CTSA 550KR71418 (E.G.L.), NIH/CTSA 550KR61325 (E.G.L.), NSF/CBET 1133427 and 1702841 (E.G.L.) and NIH/COBRE P20GM109095 (J.T.O.) and NIH/INBRE P20GM103408 (J.T.O.). The 3D-bioplotting aspect of this study was supported by a grant from NCSU Faculty Research and Professional Development (FRPD) program (RAS)."

 

7

Bond D, Goddard B, Singleterry R Jr, Bilbao y León S.

Whole body effective dose equivalent dataset for MAX and FAX shielded with common aerospace materials in deep space.

Data Brief. 2020 Feb;28:104885.

https://www.ncbi.nlm.nih.gov/pubmed/31886346

Note: From the abstract: "The data in this article is used for the paper, 'Evaluating the effectiveness of common aerospace materials at lowering the whole body effective dose equivalent in deep space.' " (Bond DK, Goddard B, Singleterry RC Jr, Bilbao y León S. Evaluating the effectiveness of common aerospace materials at lowering the whole body effective dose equivalent in deep space. Acta Astronaut. 2019 Dec;165:68-95. Epub 2019 Aug 22. http://www.sciencedirect.com/science/article/pii/S0094576519311853, which appeared in SPACELINE Current Awareness List #863, 30 Aug 2019.)  This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: No funding cited. R. Singleterry Jr is affiliated with NASA Johnson Space Center.

 

8

Huang EG, Wang R, Xie L, Chang P, Yao G, Zhang B, Ham DW, Lin Y, Blakely E, Sachs R.

Simulating galactic cosmic ray effects: Synergy modeling of murine tumor prevalence after exposure to two one-ion beams in rapid sequence.

Life Sci Space Res. 2020 Jan 7. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552420300018

PI: E.A. Blakely

Journal Impact Factor: 2.066

Funding: "EAB, PYC, and RKS gratefully acknowledge funding support from NASA [Grant no. NNJ16HP22I (EAB)], under the auspices of the U.S. Department of Energy Office of Science under Contract No. DE-AC02-05CH11231."

 

9

Jones CB, Davis CM, Sfanos KS.

The potential effects of radiation on the gut-brain axis.

Radiat Res. 2020 Jan 3. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31898468

PI: C.M. Davis/VNSCOR

Journal Impact Factor: 2.530

Funding: "We gratefully acknowledge Space@Hopkins (to CBJ, CMD and KSS) and the National Aeronautics and Space Administration (NASA funding no. 80NSSC18K1080 to CMD) for research support, as well as the Pathobiology Graduate Program at the Johns Hopkins University School of Medicine."

______________________________________________________

 

Other papers of interest:

 

1

Häder DP.

On the way to Mars—Flagellated algae in bioregenerative life support systems under microgravity conditions.

Front Plant Sci. 2020 Jan 8;10:1621. Review.

https://www.frontiersin.org/article/10.3389/fpls.2019.01621

Note: Foton M1, Foton M3 results are discussed. This article may be obtained online without charge.

 

2

Dubayle D, Vanden-Bossche A, Beraneck M, Vico L, Morel J-L.

Effects of centrifugation and whole-body vibrations on blood-brain barrier permeability in mice.

npj Microgravity. 2020 Jan 7;6(1):1.

https://www.nature.com/articles/s41526-019-0094-z

Note: Centrifugation and whole body vibration were used. This article may be obtained online without charge.

 

3

Strube F, Infanger M, Dietz C, Romswinkel A, Kraus A.

Short-term effects of simulated microgravity on morphology and gene expression in human breast cancer cells.

Physiol Int. 2019 Dec;106(4):311-22.

https://www.ncbi.nlm.nih.gov/pubmed/31896265

Note: A random positioning machine was used.

 

4

Lipman GS, Marvel JT, Burns P.

Re: "Ultrasound in austere environments" by Canepa and Harris.

High Alt Med Biol. 2019 Dec;20(4):440.

https://www.ncbi.nlm.nih.gov/pubmed/31880496

Note: The authors comment on: Canepa CA, Harris NS. Clinician's corner: Ultrasound in austere environments. High Alt Med Biol.  2019 Jun;20(2):103-111. https://www.ncbi.nlm.nih.gov/pubmed/31112050, which appeared in SPACELINE Current Awareness List #851, 31 May 2019.

 

5

Harris NS.

Response to Lipman et al. re: "Ultrasound in austere environments."

High Alt Med Biol. 2019 Dec;20(4):441.

https://www.ncbi.nlm.nih.gov/pubmed/31880495

Note: The author responds to #4 above.

 

6

Kimbara Y, Shimada Y, Kuboyama T, Tohda C.

Cistanche tubulosa (Schenk) Wight extract enhances hindlimb performance and attenuates myosin heavy chain IId/IIx expression in cast-immobilized mice.

Evid Based Complement Alternat Med. 2019 Oct 22;2019:9283171.

https://www.ncbi.nlm.nih.gov/pubmed/31885674

Note: Hindlimb immobilization was accomplished via casting. This article may be obtained online without charge.

 

7

Salucci S, Falcieri E.

Polyphenols and their potential role in preventing skeletal muscle atrophy.

Nutr Res. 2019 Nov 20;74:10-22. Review.

https://www.ncbi.nlm.nih.gov/pubmed/31895993

 

8

Kaiser J, Allaire B, Fein PM, Lu D, Adams A, Kiel DP, Jarraya M, Guermazi A, Demissie S, Samelson EJ, Bouxsein ML, Morgan EF.

Heterogeneity and spatial distribution of intravertebral trabecular bone mineral density in the lumbar spine is associated with prevalent vertebral fracture.

J Bone Miner Res. 2019 Dec 30. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31886907

 

9

Williams JA, Windmill JFC, Tanner KE, Riddell JS, Coupaud S.

Global and site-specific analysis of bone in a rat model of spinal cord injury-induced osteoporosis.

Bone Rep. 2020 Jun;12:100233. Epub 2019 Nov 29.

https://www.ncbi.nlm.nih.gov/pubmed/31886322

Note: This article may be obtained online without charge.

 

10

Elbakrawy EM, Hill MA, Kadhim MA.

Radiation-induced chromosome instability: The role of dose and dose rate.

Genome Integr. 2019 Oct 25;10:3.

https://www.ncbi.nlm.nih.gov/pubmed/31897286

Note: This article may be obtained online without charge.

 

11

Wang Q, Pujol-Canadell M, Taveras M, Garty G, Perrier J, Bueno-Beti C, Shuryak I, Brenner DJ, Turner HC.

DNA damage response in peripheral mouse blood leukocytes in vivo after variable, low-dose rate exposure.

Radiat Environ Biophys. 2020 Jan 2. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31897603

 

12

Yamaguchi M, Nishida T, Sato Y, Nakai Y, Kashiwakura I.

Identification of radiation-dose-dependent expressive genes in individuals exposed to external ionizing radiation.

Radiat Res. 2020 Jan 7. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31910119

 

13

Li ZM, Liu H, Zhang WZ, Liu H.

Psychophysiological and cognitive effects of strawberry plants on people in isolated environments.

J Zhejiang Univ Sci B. 2020 Jan.;21(1):53-63.

https://www.ncbi.nlm.nih.gov/pubmed/31898442

Note: Researchers assessed the effects of viewing strawberry plants on the mood as indicated by heart rate, salivary cortisol, and psychological scales. The experiment was repeated in the Lunar Palace 1, a bioregenerative life support system (BLSS) used as an analog space station. This article may be obtained online without charge.

 

14

Klaus MP, Schöne CG, Hartmann M, Merfeld DM, Schubert MC, Mast FW.

Roll tilt self-motion direction discrimination training: First evidence for perceptual learning.

Atten Percept Psychophys. 2020 Jan 2. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31898068

 

15

Mshelmbula B, Akomolafe G.

Preliminary effect of centrifugal force on germination and early growth of maize (Zea Mays L.).

Trans Sci Tech. 2019 Dec;8(4):328 - 33.

http://tost.unise.org/pdfs/vol6/no4/vol6n4.html

Note: Centrifugation was used. This article may be obtained online without charge.

 

16

Rana BB, Kamimukai M, Bhattarai M, Koide Y, Murai M.

Responses of earliness and lateness genes for heading to different photoperiods, and specific response of a gene or a pair of genes to short day length in rice.

Hereditas. 2019 Dec 18;156:36.

https://www.ncbi.nlm.nih.gov/pubmed/31889942

Note: This article may be obtained online without charge.

 

17

Lauridsen KG, Watanabe I, Løfgren B, Cheng A, Duval-Arnould J, Hunt EA, Good GL, Niles D, Berg RA, Nishisaki A, Nadkarni VM.

Standardising communication to improve in-hospital cardiopulmonary resuscitation.

Resuscitation. 2019 Dec 28. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31891790

Note: The NASA Task Load Index was used.

...

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