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NASA Spaceline Current Awareness List #858 19 July 2019 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, July 19, 2019

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website athttps://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

 

 

Papers deriving from NASA support:

 

1

Voorhies AA, Ott MC, Mehta S, Pierson DL, Crucian BE, Feiveson A, Oubre CM, Torralba M, Moncera K, Zhang Y, Zurek E, Lorenzi HA.

Study of the impact of long-duration space missions at the International Space Station on the astronaut microbiome.

Sci Rep. 2019 Jul 9;9(1):9911.

https://www.ncbi.nlm.nih.gov/pubmed/31289321

PI: H.A. Lorenzi

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: 4.011

Funding: "This work was supported by the NASA Human Research Program under grant number NNX12AB02G."

 

2

Grover K, Hu M, Lin L, Muir J, Qin YX.

Functional disuse initiates medullary endosteal micro-architectural impairment in cortical bone characterized by nanoindentation.

J Bone Miner Metab. 2019 Jul 10. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31292723

PI: Y.X. Qin

Note: Hindlimb unloading study.

Journal Impact Factor: 2.310

Funding: "This work is kindly supported by the National Institute of Health (R01 AR52379 and R01AR61821), the US Army Medical Research and Materiel Command, The National Space Biomedical Research Institute through NASA contract NCC 9-58."

 

3

Plante I, Ponomarev A, Patel Z, Slaba T, Hada M.

RITCARD: Radiation-induced tracks, chromosome aberrations, repair and damage.

Radiat Res. 2019 Jul 11. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31295089

PI: M. Hada

Journal Impact Factor: 2.530

Funding: "This work was supported by NASA Space Radiation Program (grant no. NNX16AR97G to MH), NASA Human Health and Performance Contract (HHPC; no. NNJ15HK11B), and TAMU Chancellor’s Research Initiative, Texas A&M University."

 

4

Whitman K, Norbury JW, Lee K, Slaba TC, Badavi FF.

Comparison of space radiation GCR models to AMS heavy ion data.

Life Sci Space Res. 2019 Jul 12. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552419300483

PI: J.W. Norbury

Journal Impact Factor: 2.066

Funding: "This work was supported by the Advanced Exploration Systems (AES) Division under the Human Exploration and Operations Mission Directorate of NASA."

 

5

Ronca AE, Moyer EL, Talyansky Y, Lowe M, Padmanabhan S, Choi S, Gong C, Cadena SM, Stodieck L, Globus RK.

Author Correction: Behavior of mice aboard the International Space Station.

Sci Rep. 2019 Jul 9;9(1):10154.

https://www.ncbi.nlm.nih.gov/pubmed/31289284

Note: Corrections were made to an author address and, in the abstract, the number of days after launch that mice began circling behavior. The original article was: Ronca AE, Moyer EL, Talyansky Y, Lowe M, Padmanabhan S, Choi S, Gong C, Cadena SM, Stodieck L, Globus RK. Behavior of mice aboard the International Space Station. Sci Rep. 2019 Apr 11;9(1):4717. https://www.ncbi.nlm.nih.gov/pubmed/30976012, and was cited in SPACELINE Current Awareness List #845, 19 Apr 2019. The original article has been corrected and may be obtained online without charge.

Journal Impact Factor: 4.011

Funding: From the original article: "Funding was provided by the NASA Ames Research Center Space Biology Program, Rodent Research Project, and Center Directors Fund."

 

6

Scheuring RA, Schmid JF, Polk JD.

Environmental extremes: Space.

In: O'Connor FG, Schoomaker EB, Smith DC, eds. Fundamentals of Military Medicine. Textbooks of Military Medicine. Ft. Sam Houston, TX: Borden Institute, 2019. p. 347-62.

https://www.cs.amedd.army.mil/borden/bookDetail.aspx?ID=a875991f-3640-4cab-afa5-66f02f917333%20&pageTitle=Fundamentals%20of%20Military%20Medicine

Journal Impact Factor: Not applicable to this publication

Funding: No funding cited. J.D. Polk is affiliated with NASA Headquarters.

 

7

International Space Station Benefits for Humanity.

Houston, TX: NASA Johnson Space Center, 2019. 236 p. NP-2018-06-013-JSC.

https://www.nasa.gov/mission_pages/station/research/news/b4h-3rd-ed-book 

Note: The book is a collaborative work by the members of the International Space Station Program Science Forum: National Aeronautics and Space Administration, Canadian Space Agency, European Space Agency, Japan Aerospace Exploration Agency, Russian Federal Space Agency, and Italian Space Agency. From the Executive Summary: "The third edition of the International Space Station Benefits for Humanity is a compilation of benefits being realized from International Space Station (ISS) activities in the areas of human health, Earth observations and disaster response, innovative technology, global education, and economic development of space. This revision also includes new assessments of economic value and scientific value in more detail than the second edition. The third edition contains updated statistics on the impacts of the benefits as well as new benefits that have developed since the previous publication. International Space Station Benefits for Humanity is a product of the ISS Program Science Forum (PSF), which consists of senior science representatives across the ISS international partnership." This publication may be obtained online without charge.

Journal Impact Factor: Not applicable to this publication

Funding: From the acknowledgements: "A Product of the International Space Station Program Science Forum."

______________________________________________________

 

 

Other papers of interest:

 

1

Tseng WS, Chien WC, Chung CH, Chou YC, Tzeng NS.

Risk of sleep disorders in patients with decompression sickness: A nationwide, population-based study in Taiwan.

Psychiatr Danub. 2019 Jun;31(2):172-81.

https://www.ncbi.nlm.nih.gov/pubmed/31291221

Note: This article may be obtained online without charge.

 

2

Jalal N, Gracies JM, Zidi M.

Mechanical and microstructural changes of skeletal muscle following immobilization and/or stroke.

Biomech Model Mechanobiol. 2019 Jul 6. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31280449

Note: Rat forelimb immobilization was used.

 

3

Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, Zhou C, Chou J, Parkman VA, Novick SJ, Strutzenberg TS, Pascal BD, Le PT, Brooks DJ, Roche AM, Gerber KK, Mattheis L, Chen W, Tu H, Bouxsein ML, Griffin PR, Baron R, Rosen CJ, Bonewald LF, Spiegelman BM.

Irisin mediates effects on bone and fat via αV integrin receptors [Erratum].

Cell. 2019 Jul 11;178(2):507-8.

https://www.ncbi.nlm.nih.gov/pubmed/31299203

Note: From the authors: "Our paper identified αV integrins as the cellular receptors for irisin, acting in osteocytes and adipocytes. During figure preparation, we inadvertently duplicated the β-actin western blot image from Figure S6A in Figure S4C. We have now corrected Figure S4C with the β-actin control that was executed with the experiment shown. In addition, in Figure S4D, the protein integrin α was mistakenly labeled as "integrin αV." This label has been amended. The corrected figure appears below and in the paper online. We apologize for any confusion this duplication may have caused." The original article was: Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, Zhou C, Chou J, Parkman VA, Novick SJ, Strutzenberg TS, Pascal BD, Le PT, Brooks DJ, Roche AM, Gerber KK, Mattheis L, Chen W, Tu H, Bouxsein ML, Griffin PR, Baron R, Rosen CJ, Bonewald LF, Spiegelman BM. Irisin mediates effects on bone and fat via ɑV integrin receptors. Cell. 2018 Dec 13;175(7):1756-68.e17. https://www.ncbi.nlm.nih.gov/pubmed/30550785. It was cited in SPACELINE Current Awareness List #829, 21 Dec 2018. The author correction may be obtained online without charge.

 

4

Kirby TJ.

Mechanosensitive pathways controlling translation regulatory processes in skeletal muscle and implications for adaptation.

J Appl Physiol (1985). 2019 Jul 11. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/31295035

 

5

Sun W, Chi S, Li Y, Ling S, Tan Y, Xu Y, Jiang F, Li J, Liu C, Zhong G, Cao D, Jin X, Zhao D, Gao X, Liu Z, Xiao B, Li Y.

The mechanosensitive Piezo1 channel is required for bone formation.

Elife. 2019 Jul 10;8:e47454.

https://www.ncbi.nlm.nih.gov/pubmed/31290742

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

6

Yang PF, Nie XT, Wang Z, Al-Qudsy LHH, Ren L, Xu HY, Rittweger J, Shang P.

Disuse impairs the mechanical competence of bone by regulating the characterizations of mineralized collagen fibrils in cortical bone.

Front Physiol. 2019 Jun 21;10:775.

https://www.ncbi.nlm.nih.gov/pubmed/31293444

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

7

Li Q, Li K, Zhang S, Zhou Y, Hong J, Zhou X, Li Z, Wu B, Wu G, Meng R.

The effect of ionizing radiation on the subcellular localization and kinase activity of protein kinase CK2 in human non-small cell lung cancer cells.

Int J Radiat Biol. 2019 Jul 10. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31290713

 

8

Liu R, Zhao T, Swat MH, Reynoso FJ, Higley KA.

Development of computational model for cell dose and DNA damage quantification of multicellular system.

Int J Radiat Biol. 2019 Jul 10. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31290712

 

9

Razskazovskiy Y, Tegomoh M, Roginskaya M.

Association with polyamines and polypeptides increases the relative yield of 2-deoxyribonolactone lesions in radiation-damaged DNA.

Radiat Res. 2019 Jul 12. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31298612

 

10

Royba E, Repin M, Pampou S, Karan C, Brenner DJ, Garty G.

RABiT-II-DCA: A fully-automated dicentric chromosome assay in multiwell plates.

Radiat Res. 2019 Jul 11. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31295087

 

11

Saif-Elnasr M, Abdel Fattah SM, Swailam HM.

Treatment of hepatotoxicity induced by γ-radiation using platelet rich plasma and/or low molecular weight chitosan in experimental rats.

Int J Radiat Biol. 2019 Jul 10. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31290709

 

12

Song CH, Joo HM, Han SH, Kim JI, Nam SY, Kim JY.

Low-dose ionizing radiation attenuates mast cell migration through suppression of monocyte chemoattractant protein-1 (MCP-1) expression by Nr4a2.

Int J Radiat Biol. 2019 Jul 9. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31287373

 

13

Yushkova E.

Effects of ionizing radiation at Drosophila melanogaster with differently active hobo transposons.

Int J Radiat Biol. 2019 Jul 9. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31287364

 

14

Dias RD, Zenati MA, Stevens R, Gabany JM, Yule SJ.

Physiological synchronization and entropy as measures of team cognitive load.

J Biomed Inform. 2019 Jul 8. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31295623

 

15

Ma Q, Sandal GM, Wu R, Xiong J, Li Y, Xu Z, He L, Liu Y.

Personal value diversity in confinement and isolation: Pilot study results from the 180-day CELSS integration experiment.

Acta Astronaut. 2019 Jul 12. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0094576519303418

Note: Results are reported from a 180-day study in the Chinese Controlled Ecological Life Support System (CELSS).

 

16

Martins-Lopes V, Bellmunt A, Greguske EA, Maroto AF, Boadas-Vaello P, Llorens J.

Quantitative assessment of anti-gravity reflexes to evaluate vestibular dysfunction in rats.

J Assoc Res Otolaryngol. 2019 Jul 11. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31297642

Note: Vestibular dysfunction was elicited by acute or sub-chronic exposure to 3,3'-iminodipropionitrile (IDPN).

 

17

Sayyid ZN, Wang T, Chen L, Jones SM, Cheng AG.

Atoh1 directs regeneration and functional recovery of the mature mouse vestibular system.

Cell Rep. 2019 Jul 9;28(2):312-24.e4.

https://www.ncbi.nlm.nih.gov/pubmed/31291569

Note: This article may be obtained online without charge.

 

18

Lewkowicz R.

A centrifuge-based flight simulator: Optimization of a baseline acceleration profile based on the motion sickness incidence.

Acta Astronaut. 2019 Nov;164:23-33. Epub 2019 Jul 12.

http://www.sciencedirect.com/science/article/pii/S0094576518317296

Note: A centrifuge was used.

 

19

Rakici SY, Tumkaya L, Celebi Edirvanli O, Yazici U, Dursun E, Arpa M, Mercantepe T.

Radioprotective effect of endogenous melatonin secretion associated with the circadian rhythm in irradiated rats.

Int J Radiat Biol. 2019 Jul 9. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31287351

 

20

Spitschan M, Stefani O, Blattner P, Gronfier C, Lockley SW, Lucas RJ.

How to report light exposure in human chronobiology and sleep research experiments.

Clocks Sleep. 2019 Jul 1;1(3):280-9.

https://www.ncbi.nlm.nih.gov/pubmed/31281903

Note: This article may be obtained online without charge beginning September 1, 2019.

 

21

Ogura T, Goeschl C, Filiault D, Mirea M, Slovak R, Wolhrab B, Satbhai SB, Busch W.

Root system depth in Arabidopsis is shaped by EXOCYST70A3 via the dynamic modulation of auxin transport.

Cell. 2019 Jul 11;178(2):400-12.e16.

https://www.ncbi.nlm.nih.gov/pubmed/31299202

 

22

Tada Y.

The HKT transporter gene from Arabidopsis, AtHKT1;1, is dominantly expressed in shoot vascular tissue and root tips and is mild salt stress-responsive.

Plants (Basel). 2019 Jul 4;8(7):E204.

https://www.ncbi.nlm.nih.gov/pubmed/31277362

Note: This article may be obtained online without charge.

 

23

Wang M, Dong C, Gao W.

Evaluation of the growth, photosynthetic characteristics, antioxidant capacity, biomass yield and quality of tomato using aeroponics, hydroponics and porous tube-vermiculite systems in bio-regenerative life support systems.

Life Sci Space Res. 2019 Aug;22:68-75.

http://www.sciencedirect.com/science/article/pii/S221455241930001X

 

24

Melo HM, Hoeller AA, Walz R, Takase E.

Resting cardiac vagal tone is associated with long-term frustration level of mental workload: Ultra-short term recording reliability.

Appl Psychophysiol Biofeedback. 2019 Jul 8. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31286301

Note: The NASA Task Load Index was used.

// end //

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