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NASA Spaceline Current Awareness List #852 7 June 2019 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, June 7, 2019

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website athttps://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

 

Papers deriving from NASA support:

 

1

Traina-Dorge V, Mehta S, Rooney B, Crucian B, Doyle-Meyers L, Das A, Coleman C, Nagel M, Mahalingam R.

Simian varicella virus DNA in saliva and buccal cells after experimental acute infection in rhesus macaques.

Front Microbiol. 2019 May 9;10:1009.

https://www.ncbi.nlm.nih.gov/pubmed/31143167

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.019

Funding: "This work was supported in part by Public Health Service grants AG032958 (to RM, VT-D, AD, LD-M, MN) from the National Institutes of Health and NASA Grants 111-30-10-03 and 111-3010-06 (SM, BR, BC), and in part, with federal funds from the National Center for Research Resources and the Office of Research Infrastructure Programs (ORIP) of the NIH through grant P51 OD011104 to the Tulane National Primate Research Center (VT-D, AD, LD-M)."

 

2

Blue RS, Chancellor JC, Antonsen EL, Bayuse TM, Daniels VR, Wotring VE.

Limitations in predicting radiation-induced pharmaceutical instability during long-duration spaceflight.

npj Microgravity. 2019 Jun 6;5(1):15.

https://www.nature.com/articles/s41526-019-0076-1

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.00

Funding: No funding cited. E.L. Antonsen is affiliated with NASA Johnson Space Center.

 

3

Bokhari RS, Metzger CE, Black JM, Franklin KA, Boudreaux RD, Allen MR, Macias BR, Hogan HA, Braby LA, Bloomfield SA.

Positive impact of low-dose, high-energy radiation on bone in partial- and/or full-weightbearing mice.

npj Microgravity. 2019 Jun 4;5(1):13.

https://www.nature.com/articles/s41526-019-0074-3

PI: S.A. Bloomfield

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.00

Funding: "These experiments were funded by NASA Cooperative Agreement NCC 9-58 with National Space Biomedical Research Institute (S. Bloomfield, PI). The open access publishing fees for this article have been covered by the Texas A&M University Open Access to Knowledge Fund (OAKFund), supported by the University Libraries and the Office of the Vice President for Research."

 

4

Miousse IR, Skinner CM, Sridharan V, Seawright JW, Singh P, Landes RD, Cheema AK, Hauer-Jensen M, Boerma M, Koturbash I.

Changes in one-carbon metabolism and DNA methylation in the hearts of mice exposed to space environment-relevant doses of oxygen ions (16O).

Life Sci Space Res. 2019 Aug;22:8-15. Epub 2019 May 31.

http://www.sciencedirect.com/science/article/pii/S2214552418300828

PIs: M. Boerma/M. Hauer-Jensen/I. Koturbash/Center for Research on Cardiac, Vascular, and Acute Effects of Space Radiation

Journal Impact Factor: 1.97

Funding: "The study was supported in part by the National Space Biomedical Research Institute through NCC 9–58 (MB), and Centers of Biomedical Research Excellence (P20, GM109005, MHJ and IK)."

 

5

Engler ST, Binsted K, Leung H.

HI-SEAS habitat energy requirements and forecasting.

Acta Astronaut. 2019 Sep;162:50-5. Epub 2019 May 31.

http://www.sciencedirect.com/science/article/pii/S0094576518302674

PI: K. Binsted

Journal Impact Factor: 2.227

Funding: "This work was made possible through NASA HFBP grants NNX11AE53G, NNX13AM78G, and NNX15AN05G, ICS department of the University of Hawaii, ground support from Blue Planet Research Inc., and the HI-SEAS mission support volunteers."

 

6

Marcec MJ, Gilroy S, Poovaiah BW, Tanaka K.

Mutual interplay of Ca2+ and ROS signaling in plant immune response.

Plant Sci. 2019 Jun;283:343-54. Review.

https://www.ncbi.nlm.nih.gov/pubmed/31128705

PI: S. Gilroy

Journal Impact Factor: 3.712

Funding: "The work was supported by USDA NIFA (Hatch project 1015621) and NSFIOS-1557813 to K.T., NSF IOS-1021344 to B.W.P., NSF IOS-1557899 and NASA NNX14AT25G/ NNX17AD52G to S.G., and the NIH Biotechnology Training Program to M.J.M. PPNS No. 0771, Department of Plant Pathology, College of Agriculture, Human and Natural Resource Sciences, Agricultural Research Center, Washington State University, Pullman, WA 99164-6430, USA."

 

Please Note: The June issue of Neurology India (vol. 67, no. 8, Supplement) is a special issue entitled "Extra-Terrestrial Neurosciences," edited by K. Ganapathy. The idea for the issue came from the announcement by the Indian Space Research Organisation that India would send a manned mission into Low Earth Orbit. Articles by NASA-affiliated authors appear here; those by non-NASA authors appear at the end of the ‘Other papers of interest’ section.

 

7

Andrews RJ.

Fallout of space technology for neurosciences on Earth.

Neurol India. 2019 May-Jun;67(8):172-3.

https://www.ncbi.nlm.nih.gov/pubmed/31134906

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.166

Funding: No funding cited. R.J. Andrews is affiliated with NASA Ames Research Center.

 

8

Kandarpa K, Schneider V, Ganapathy K.

Human health during space travel: An overview.

Neurol India. 2019 May-Jun;67(8):176-81. Review.

https://www.ncbi.nlm.nih.gov/pubmed/31134907

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.166

Funding: No funding cited. V. Schneider is affiliated with NASA Headquarters.

 

9

Doarn CR, Polk JD, Shepanek M.

Health challenges including behavioral problems in long-duration spaceflight.

Neurol India. 2019 May-Jun;67(8):190-5. Review.

https://www.ncbi.nlm.nih.gov/pubmed/31134909

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.166

Funding: No funding cited. The authors are affiliated with NASA Headquarters.

 

10

Mann V, Sundaresan A, Mehta SK, Crucian B, Doursout MF, Devakottai S.

Effects of microgravity and other space stressors in immunosuppression and viral reactivation with potential nervous system involvement.

Neurol India. 2019 May-Jun;67(8):198-203. Review.

https://www.ncbi.nlm.nih.gov/pubmed/31134910

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.166

Funding: No funding cited. S.K. Mehta and B. Crucian are affiliated with NASA Johnson Space Center.

________________________________________________________

 

 

Other papers of interest:

 

1

Krüger M, Melnik D, Kopp S, Buken C, Sahana J, Bauer J, Wehland M, Hemmersbach R, Corydon TJ, Infanger M, Grimm D.

Fighting thyroid cancer with microgravity research.

Int J Mol Sci. 2019 May 24;20(10):E2553. Review.

https://www.ncbi.nlm.nih.gov/pubmed/31137658

Note: The authors review thyroid cell studies conducted during spaceflight, parabolic flight, and on sounding rockets, as well as in simulated microgravity (clinostats, rotating wall vessels, and random positioning machines). This article may be obtained online without charge.

 

2

Loktev SS, Ogneva IV.

DNA methylation of mouse testes, cardiac and lung tissue during long-term microgravity simulation.

Sci Rep. 2019 May 28;9(1):7974.

https://www.ncbi.nlm.nih.gov/pubmed/31138883

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

3

Aversa Z, Zhang X, Fielding RA, Lanza I, LeBrasseur NK.

The clinical impact and biological mechanisms of skeletal muscle aging.

Bone. 2019 Oct;127:26-36. Epub May 22.

https://www.ncbi.nlm.nih.gov/pubmed/31128290

 

4

Gardell SJ, Zhang X, Kapoor N, Petucci C, Coen PM.

Metabolomics analyses of muscle atrophy induced by hind limb unloading.

Methods Mol Biol. 2019;1996:297-309.

https://www.ncbi.nlm.nih.gov/pubmed/31127563

Note: Hindlimb unloading study.

 

5

Gao Y, Li T, Sun Q, Huo B.

Gradient fluid shear stress regulates migration of osteoclast precursors.

Cell Adh Migr. 2019 Dec;13(1):183-91. Epub 2019 May 28.

https://www.ncbi.nlm.nih.gov/pubmed/31131719

Note: This article may be obtained online without charge.

 

6

Qin W, Liu L, Wang Y, Wang Z, Yang A, Wang T.

Mir-494 inhibits osteoblast differentiation by regulating BMP signaling in simulated microgravity.

Endocrine. 2019 May 25. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31129811

Note: Hindlimb unloading study.

 

7

Srinivasan S, Balsiger D, Huber P, Ausk BJ, Bain SD, Gardiner EM, Gross TS.

Static preload inhibits loading-induced bone formation.

JBMR Plus. 2019 May;3(5):e10087. Epub 2018 Oct 11.

https://www.ncbi.nlm.nih.gov/pubmed/31131340

Note: This article may be obtained online without charge.

 

8

Caplin N, Willey N.

Predicting the effects of low dose-rate ionizing radiation on redox potential in plant cells.

Methods Mol Biol. 2019;1990:135-42.

https://www.ncbi.nlm.nih.gov/pubmed/31148068

 

9

Michalson KT, Macintyre AN, Sempowski GD, Bourland JD, Howard TD, Hawkins GA, Dugan GO, Cline JM, Register TC.

Monocyte polarization is altered by total-body irradiation in male rhesus macaques: Implications for delayed effects of acute radiation exposure.

Radiat Res. 2019 Jun 4. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31161966

 

10

Puukila S, Muise S, McEvoy J, Bouchier T, Hooker AM, Boreham DR, Khaper N, Dixon DL.

Acute pulmonary and splenic response in an in vivo model of whole-body low-dose X-radiation exposure.

Int J Radiat Biol. 2019 May 29. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31140892

 

11

Thür C, Roel Lesur M, Bockisch CJ, Lopez C, Lenggenhager B.

The tilted self: Visuo-graviceptive mismatch in the full-body illusion.

Front Neurol. 2019 May 8;10:436.

https://www.ncbi.nlm.nih.gov/pubmed/31133959

Note: From the abstract: "The present experiment investigates the influence of conflicting gravity-related visual and bodily information on the sense of a body and, vice versa, the influence of altered embodiment on verticality and own-body orientation perception." This article may be obtained online without charge.

 

12

Tighilet B, Bordiga P, Cassel R, Chabbert C.

Peripheral vestibular plasticity vs central compensation: Evidence and questions.

J Neurol. 2019 May 27. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31134376

 

13

Murray JM, Phillips AJK, Magee M, Sletten TL, Gordon C, Lovato N, Bei B, Bartlett DJ, Kennaway DJ, Lack LC, Grunstein RR, Lockley SW, Rajaratnam SMW.

Sleep regularity is associated with sleep-wake and circadian timing, and mediates daytime function in Delayed Sleep-Wake Phase Disorder.

Sleep Med. 2019 Jun;58:93-101.

https://www.ncbi.nlm.nih.gov/pubmed/31132578

 

14

Wolkow AP, Barger LK, O'Brien CS, Sullivan JP, Qadri S, Lockley SW, Czeisler CA, Rajaratnam SMW.

Associations between sleep disturbances, mental health outcomes and burnout in firefighters, and the mediating role of sleep during overnight work: A cross-sectional study.

J Sleep Res. 2019 May 26. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31131535

 

15

Kirkpatrick MAW.

Point-of-care resuscitation research: From extreme to mainstream: Trauma Association of Canada Fraser Gurd Lecture 2019.

J Trauma Acute Care Surg. 2019 May 24. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31136525

Note: Parabolic flight studies are discussed. "This manuscript was an invited Podium Presentation at the Annual Scientific Meeting of the Trauma Association of Canada, as the named Fraser Gurd Lecture 2019."

 

16

Sundaram S, Kellnhofer P, Li Y, Zhu JY, Torralba A, Matusik W.

Learning the signatures of the human grasp using a scalable tactile glove.

Nature. 2019 May;569(7758):698-702.

https://www.ncbi.nlm.nih.gov/pubmed/31142856

 

17

Zou Y, Qin T, Wang N, Li J, Xu M.

Passive force control of multimodal astronaut training robot.

Int J Adv Robot Syst. 2019 May 29;16(3):1-9.

https://journals.sagepub.com/doi/10.1177/1729881419848261

Note: This article may be obtained online without charge.

 

18

Wahba R, Datta RR, Hedergott A, Bußhoff J, Bruns T, Kleinert R, Dieplinger G, Fuchs H, Giezelt C, Möller D, Hellmich M, Bruns CJ, Stippel DL.

3D vs. 4K display system - Influence of "State-of-the-art" - Display technique on Surgical Performance (IDOSP-Study) in minimally invasive surgery: Protocol for a randomized cross-over trial.

Trials. 2019 May 28;20(1):299.

https://www.ncbi.nlm.nih.gov/pubmed/31138290

Note: The NASA Task Load Index was used. This article may be obtained online without charge.

 

19

Zargari Marandi R, Madeleine P, Omland Ø, Vuillerme N, Samani A.

An oculometrics-based biofeedback system to impede fatigue development during computer work: A proof-of-concept study.

PLoS One. 2019 May 31;14(5):e0213704.

https://www.ncbi.nlm.nih.gov/pubmed/31150405

Note: The NASA Task Load Index was used. This article may be obtained online without charge.

 

 

Please Note: The remaining articles from the Neurology India special issue, "Extra-Terrestrial Neurosciences," are listed below:

 

20

Ganapathy K.

Extra-terrestrial neurosciences.

Neurol India. 2019 May-Jun;67(8):165-6.

https://www.ncbi.nlm.nih.gov/pubmed/31134902

Note: This article may be obtained online without charge.

 

21

Nair SU.

Challenges to human spaceflight program: The emerging role of bioastronautics.

Neurol India. 2019 May-Jun;67(8):167-8.

https://www.ncbi.nlm.nih.gov/pubmed/31134903

Note: This article may be obtained online without charge.

 

22

Agarwal A.

Human spaceflight from one's own soil.

Neurol India. 2019 May-Jun;67(6):169.

https://www.ncbi.nlm.nih.gov/pubmed/31134904

Note: This article may be obtained online without charge.

 

23

Sharma R.

Likely challenges facing future astronauts assigned to long duration space flights.

Neurol India. 2019 May-Jun;67(8):170-1.

https://www.ncbi.nlm.nih.gov/pubmed/31134905

Note: This article may be obtained online without charge.

 

24

Frantzidis CA, Kontana E, Karkala A, Nigdelis V, Karagianni M, Nday CM, Ganapathy K, Kourtidou-Papadeli C.

Current trends and future perspectives of space neuroscience towards preparation for interplanetary missions.

Neurol India. 2019 May-Jun;67(8):182-7. Review.

https://www.ncbi.nlm.nih.gov/pubmed/31134908

Note: This article may be obtained online without charge.

 

25

Mader TH, Gibson CR, Miller NR, Subramanian PS, Patel NB, Lee AG.

An overview of spaceflight-associated neuro-ocular syndrome (SANS).

Neurol India. 2019 May-Jun;67(8):206-11. Review.

https://www.ncbi.nlm.nih.gov/pubmed/31134911 

Note: This citation appeared in SPACELINE Current Awareness List ##851, 31 May 2019; it is included here for completeness. This article may be obtained online without charge.

 

26

Russomano T, da Rosa M, Dos Santos MA.

Space motion sickness: A common neurovestibular dysfunction in microgravity.

Neurol India. 2019 May-Jun;67(8):214-8. Review.

https://www.ncbi.nlm.nih.gov/pubmed/31134912

Note: This article may be obtained online without charge.

 

27

Nday CM, Frantzidis C, Jackson G, Bamidis P, Kourtidou-Papadeli C.

Neurophysiological changes in simulated microgravity: An animal model.

Neurol India. 2019 May-Jun;67(8):221-6. Review.

https://www.ncbi.nlm.nih.gov/pubmed/31134913

Note: Hindlimb unloading methods are discussed. This article may be obtained online without charge.

 

28

Hammond BT, da Silva Melo DA, de Farias RP, da Rosa M, Lamadrid I, Disiuta L, Marquesde Lima JC, Russomano T.

Mars walking simulation: An electromyographic analysis.

Neurol India. 2019 May-Jun;67(8):230-5.

https://www.ncbi.nlm.nih.gov/pubmed/31134914

Note: Lower body positive pressure was used. This article may be obtained online without charge.

...

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