NASA Spaceline Current Awareness List #805 29 June 2018 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, June 29, 2018

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,

In case you missed it: Dr. Norman Lewis (Washington State University) was interviewed on June 8, 2018, by Hannah Whisenant of Northwest Public Broadcasting about his research. In the segment entitled “Plants in Space: Not Your Average Garden Variety Cosmos Exploration,” he discusses his study of Arabidopsis thaliana growth in space. His current project was launched in May 2018 and is now growing in the Advanced Plant Habitat onboard the International Space Station. The interview is available at:

Papers deriving from NASA support:


Ploutz-Snyder LL, Downs M, Goetchius E, Crowell B, English KL, Ploutz-Snyder R, Ryder J, Dillon EL, Sheffield-Moore M, Scott JM.

Exercise training mitigates multi-system deconditioning during bed rest.

Med Sci Sports Exerc. 2018 Mar 26. [Epub ahead of print]

PI: L.L. Ploutz-Snyder

Note: Bed rest study.

Journal Impact Factor: 4.141

Funding: "This study was supported by the Human Research Program of the National Aeronautics and Space Administration (NASA) and National Space Biomedical Research Institute (NSBRI NNJ11ZSA002N)....This study was conducted with the support of the Institute for Translational Sciences at the University of Texas Medical Branch, supported in part by a Clinical and Translational Science Award (UL1TR000071) from the National Center for Advancing Translational Sciences, National Institutes of Health."



National Academies of Sciences, Engineering, and Medicine.

A Midterm Assessment of Implementation of the Decadal Survey on Life and Physical Sciences Research at NASA.

Washington, DC: National Academies Press, 2017. 145 p. 

Note: This publication may be obtained online without charge.

Journal Impact Factor: Not applicable to this publication

Funding: "This activity was supported by Contract NNH16CE01B with the National Aeronautics and Space Administration."




Other papers of interest:



Onofri S, Selbmann L, Pacelli C, de Vera JP, Horneck G, Hallsworth JE, Zucconi L.

Integrity of the DNA and cellular ultrastructure of cryptoendolithic fungi in space or Mars conditions: A 1.5-year study at the International Space Station.

Life (Basel). 2018 Jun 19;8(2):E23.

Note: ISS results. This article may be obtained online without charge.



Malla MA, Dubey A, Yadav S, Kumar A, Hashem A, Abd Allah EF.

Understanding and designing the strategies for the microbe-mediated remediation of environmental contaminants using omics approaches.

Front Microbiol. 2018 Jun 4;9:1132.

Note: This article may be obtained online without charge.



Magnusson SP, Kjaer M.

The impact of loading, unloading, ageing and injury on the human tendon.

J Physiol. 2018 Jun 19. [Epub ahead of print]



Buffelli M, Tognana E, Cangiano A, Busetto G.

Activity-dependent vs neurotrophic modulation of acetylcholine receptor expression: Evidence from rat soleus and extensor digitorum longus muscles confirms the exclusive role of activity.

Eur J Neurosci. 2018 Jun 14. [Epub ahead of print]



Madinei S, Motabar H, Ning X.

The influence of external load configuration on trunk biomechanics and spinal loading during sudden loading.

Ergonomics. 2018 Jun 19. [Epub ahead of print]



Montero D, Oberholzer L, Haider T, Breenfeldt-Andersen A, Dandanell S, Meinild-Lundby AK, Maconochie H, Lundby C.

Increased capillary density in skeletal muscle is not associated with impaired insulin sensitivity induced by bed rest in healthy young men.

Appl Physiol Nutr Metab. 2018 Jun 19. [Epub ahead of print]

Note: Bed rest study.



Pileggi CA, Hedges CP, D'Souza RF, Durainayagam BR, Markworth JF, Hickey AJR, Mitchell CJ, Cameron-Smith D.

Exercise recovery increases skeletal muscle H2O2 emission and mitochondrial respiratory capacity following two-weeks of limb immobilization.

Free Radic Biol Med. 2018 Aug 20;124:241-8. Epub 2018 Jun 15.

Note: Knee braces were used for immobilization.



Edwards WB, Simonian N, Haider IT, Anschel AS, Chen D, Gordon KE, Gregory EK, Kim KH, Parachuri R, Troy KL, Schnitzer TJ.

Effects of teriparatide and vibration on bone mass and bone strength in people with bone loss and spinal cord injury: A randomized, controlled trial.

J Bone Miner Res. 2018 Jun 15. [Epub ahead of print]



Paul GR, Malhotra A, Müller R.

Mechanical stimuli in the local in vivo environment in bone: Computational approaches linking organ-scale loads to cellular signals.

Curr Osteoporos Rep. 2018 Jun 18. [Epub ahead of print]




Yang J, Meng X, Dong D, Xue Y, Chen X, Wang S, Shen Y, Zhang G, Shang P.

Iron overload involved in the enhancement of unloading-induced bone loss by hypomagnetic field.

Bone. 2018 Jun 18. [Epub ahead of print]

Note: Hindlimb unloading study.



de la Fuente Rosales L, Incerti S, Francis Z, Bernal MA.

Accounting for radiation-induced indirect damage on DNA with the Geant 4-DNA code.

Phys Med. 2018 Jun 13. [Epub ahead of print]



Forster JC, Douglass MJJ, Harriss-Phillips WM, Bezak E.

Monte Carlo simulation of the oxygen effect in DNA damage induction by ionizing radiation.

Radiat Res. 2018 Jun 28. [Epub ahead of print]



Wunderlich R, Rühle PF, Deloch L, Roedel F, Fietkau R, Gaipl US, Frey B.

Ionizing radiation reduces the capacity of activated macrophages to induce T-cell proliferation, but does not trigger dendritic cell-mediated non-targeted effects.

Int J Radiat Biol. 2018 Jun 18:1-36. [Epub ahead of print]



Jörges B, Hagenfeld L, López-Moliner J.

The use of visual cues in gravity judgements on parabolic motion.

Vision Res. 2018 Aug;149:47-58. Epub 2018 Jun 21.

Note: From the Introduction: "…the present study takes a look at how well the visual system computes gravity from observing its effects on the objects in a virtual environment. Furthermore, we scrutinize the roles of different visual and temporal cues humans may rely upon for their decision."



Branoner F, Straka H.

Semicircular canal influences on the developmental tuning of the translational vestibulo-ocular reflex.

Front Neurol. 2018 Jun 5;9:404.

Note: This article may be obtained online without charge.



Demidchik V, Shabala S, Isayenkov S, Cuin TA, Pottosin I.

Calcium transport across plant membranes: Mechanisms and functions.

New Phytol. 2018 Jun 19. [Epub ahead of print] Review. 



Jaroensanti-Tanaka N, Miyazaki S, Hosoi A, Tanaka K, Ito S, Iuchi S, Nakano T, Kobayashi M, Nakajima M, Asami T.

The chemical NJ15 affects hypocotyl elongation and shoot gravitropism via cutin polymerization.

Biosci Biotechnol Biochem. 2018 Jun 18. [Epub ahead of print]



Schumacher P, Demarsy E, Waridel P, Petrolati LA, Trevisan M, Fankhauser C.

A phosphorylation switch turns a positive regulator of phototropism into an inhibitor of the process.

Nat Commun. 2018 Jun 19;9(1):2403.

Note: This article may be obtained online without charge.

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