NASA Spaceline Current Awareness List #804 22 June 2018 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Sunday, June 24, 2018

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,

 Papers deriving from NASA support:


Tirumalai MR, Stepanov VG, Wunsche A, Montazari S, Gonzalez RO, Venkateswaran K, Fox GE.

Bacillus safensis FO-36b and Bacillus pumilus SAFR-032: A whole genome comparison of two spacecraft assembly facility isolates.

BMC Microbiol. 2018 Jun 8;18(1):57.

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.644

Funding: "This work was funded in part by NASA Grant NNX14AK36G to GEF."



Rooney BV, Bigley AB, LaVoy EC, Laughlin M, Pedlar C, Simpson RJ.

Lymphocytes and monocytes egress peripheral blood within minutes after cessation of steady state exercise: A detailed temporal analysis of leukocyte extravasation.

Physiol Behav. 2018 Jun 7. [Epub ahead of print]

PI: R.J. Simpson

Journal Impact Factor: 2.341

Funding: "We would like to thank Rod Azadan, Forrest Baker and Rachel Graff for their technical support. This work was supported by NASA Grants NNJ10ZSA003N, NNJ14ZSA001N-FLAGSHIP and NNJ14ZSA001N-MIXEDTOPICS and NIH Grant R21 CA197527-01A1."



Rahman M, Hewitt JE, Van-Bussel F, Edwards H, Blawzdziewicz J, Szewczyk NJ, Driscoll M, Vanapalli SA.

NemaFlex: A microfluidics-based technology for standardized measurement of muscular strength of C. elegans.

Lab Chip. 2018 Jun 12. [Epub ahead of print]

PI: S. Vanapalli

Journal Impact Factor: 6.045

Funding: "This work was partially supported by funding from NASA (Grant No. NNX15AL16G), NIH (Grant No. R21 AG050503, R01 AG051995-01A1), NSF CAREER (Grant No. 1150836), CPRIT (Grant No. RP160806), and BBSRC (grant number N015894)."



Low EK, Brudvik E, Kuhlman BM, Wilson PF, Almeida-Porada GM, Porada CD.

Microgravity impairs DNA damage repair in human hematopoietic stem/progenitor cells and inhibits their differentiation into dendritic cells.

Stem Cells Dev. 2018 Jun 14. [Epub ahead of print]

PI: C.D. Porada

Note: A rotary cell culture system was used.

Journal Impact Factor: 3.562

Funding: "This work was supported by grant # NNX17AE49G from the National Aeronautics and Space Administration (NASA) Space Biology Program."



Sng NJ, Paul A-L, Ferl RJ.

Phenotypic characterization of an Arabidopsis T-DNA insertion line SALK_063500.

Data Brief. 2018 Jun;18:913-9.

PIs: A-L. Paul, R.J. Ferl

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was supported by the NASA Space Life and Physical Sciences (SLPS) grants NNX09AL96G, NNX07AH270, NNX12AN69G and NNX14AT24G awarded to RJF and A-LP."




Other papers of interest:



Jin JP, Chen H, Cai W.

Transcriptomic analysis reveals the effects of microgravity on rice calli on board the Chinese spaceship Shenzhou 8.

Microgravity Sci Technol. 2018 Jun 14. [Article in Press]

Note: Shenzhou 8 results.



Bode F, Nastase I, Croitoru C, Sandu M, Dogeanu A, Ursu I.

Preliminary numerical studies for the improvement of the ventilation system of the crew quarters on board of the International Space Station.

INCAS Bull. 2018 Apr-Jun;10(2):137-43.  

Note: ISS study. This article may be obtained online without charge.



Receno CN, Roffo KE, Mickey MC, DeRuisseau KC, DeRuisseau LR.

Quiet breathing in hindlimb casted mice.

Respir Physiol Neurobiol. 2018 Jun 7. [Epub ahead of print]

Note: Hindlimb casting was used for immobilization.



He JP, Feng X, Wang JF, Shi WG, Li H, Danilchenko S, Kalinkevich A, Zhovner M.

Icariin prevents bone loss by inhibiting bone resorption and stabilizing bone biological apatite in a hindlimb suspension rodent model.

Acta Pharmacol Sin. 2018 Jun 11. [Epub ahead of print]

Note: Hindlimb unloading study.



Luo Y, Luo C, Cai Y, Jiang T, Chen T, Xiao W, Guo J, Fan Y.

Analysis of bone mineral density/content of paratroopers and hoopsters.

J Healthc Eng. 2018 May 20;2018:6030624.

Note: This article may be obtained online without charge.



Markina EA, Kokhan VS, Roe MP, Andrianova IV, Shtemberg AS, Buravkova LB.

The effects of radiation and hindlimb unloading on rat bone marrow progenitor cells.

Cell Tissue Biol. 2018 May 1;12(3):183-96.

Note: Hindlimb unloading study.



Grajewski B, Yong LC, Bertke SJ, Bhatti P, Little MP, Ramsey MJ, Tucker JD, Ward EM, Whelan EA, Sigurdson AJ, Waters M.

Chromosome translocations and cosmic radiation dose in male U.S. commercial airline pilots.

Aerosp Med Hum Perform. 2018 Jul;89(7):616-25. 



Rashid AM, Ramalingam L, Al-Jawadi A, Moustaid-Moussa N, Moussa H.

Low dose radiation, inflammation, cancer and chemoprevention.

Int J Radiat Biol. 2018 Jun 8. [Epub ahead of print]



Schröder S, Juerß D, Kriesen S, Manda K, Hildebrandt G.

Immunomodulatory properties of low-dose ionizing radiation on human endothelial cells.

Int J Radiat Biol. 2018 Jun 8. [Epub ahead of print]

Note: This article may be obtained online without charge.



Shao S, Gao Y, Liu J, Tian M, Gou Q, Su X.

Ferulic acid mitigates radiation injury in human umbilical vein endothelial cells in vitro via the thrombomodulin pathway.

Radiat Res. 2018 Jun 14. [Epub ahead of print]



Pettijohn KA, Geyer D, Gomez J, Becker WJ, Biggs AT.

Postural instability and simulator seasickness.

Aerosp Med Hum Perform. 2018 Jul;89(7):634-41.



Sano A, Taylor S, McHill AW, Phillips AJ, Barger LK, Klerman E, Picard R.

Identifying objective physiological markers and modifiable behaviors for self-reported stress and mental health status using wearable sensors and mobile phones: Observational study.

J Med Internet Res. 2018 Jun 8;20(6):e210.

Note: This article may be obtained online without charge.



Lazarev IE, Tomilovskaya ES, Kozlovskaya IB.

Resting state brain activity during long-term dry immersion.

Aerosp Med Hum Perform. 2018 Jul;89(7):642-7. 

Note: Dry immersion was used.



Cox SM, Ekstrom LJ, Gillis GB.

The influence of visual, vestibular and hindlimb proprioceptive ablations on landing preparation in cane toads.

Integr Comp Biol. 2018 Jun 12. [Epub ahead of print]

Note: The paper was presented at the symposium "Sensory Feedback and Animal Locomotion: Perspectives from Biology and Biorobotics" at the annual meeting of the Society for Integrative and Comparative Biology, January 5, 2018, in San Francisco, CA.



Bolkhovsky JB, Ritter FE, Chon KH, Qin M.

Performance trends during sleep deprivation on a tilt-based control task.

Aerosp Med Hum Perform. 2018 Jul;89(7):626-33. 



O'Hagan AD, Issartel J, McGinley E, Warrington G.

A pilot study exploring the effects of sleep deprivation on analogue measures of pilot competencies.

Aerosp Med Hum Perform. 2018 Jul 1;89(7):609-15.



Abbas M, Hernández-Garcia J, Pollmann S, Samodelov SL, Kolb M, Friml J, Hammes UZ, Zurbriggen MD, Blázquez MA, Alabadi D.

Auxin methylation is required for differential growth in Arabidopsis.

Proc Natl Acad Sci U S A. 2018 Jun 13. [Epub ahead of print]



Yuan P, Du L, Poovaiah BW.

Ca2+/calmodulin-dependent AtSR1/CAMTA3 plays critical roles in balancing plant growth and immunity.

Int J Mol Sci. 2018 Jun 14;19(6):1764.

Note: This article may be obtained online without charge.



Salvi AM, DeMali KA.

Mechanisms linking mechanotransduction and cell metabolism.

Curr Opin Cell Biol. 2018 Jun 11;54:114-20.



Panesar SS, Ashkan K.

Surgery in space.

BJS. 2018 Jun 19. [Epub ahead of print] Review.



Hobe S, Popova R.

Legal aspects of human orbital and suborbital spaceflight: Some legal, medical and ethical considerations.

REACH. 2018 Jun 19. [Article in Press]


// end //

More status reports and news releases or top stories.

Please follow SpaceRef on Twitter and Like us on Facebook.