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NASA Spaceline Current Awareness List #610 8 August 2014
Posted: Friday, August 8, 2014
Papers deriving from NASA support:
Yi B, Rykova M, Feuerecker M, Jäger B, Ladinig C, Basner M, Hörl M, Matzel S, Kaufmann I, Strewe C, Nichiporuk I, Vassilieva G, Rinas K, Baatout S, Schelling G, Thiel M, Dinges DF, Morukov B, Choukèr A.
520-d Isolation and confinement simulating a flight to Mars reveals heightened immune responses and alterations of leukocyte phenotype.
Funding: “A. Choukèr has received a financial support (Grant No. 50WB0919, 50WB1317) from the German Ministry of Technology and Economics (BMWi as handled by DLR). The work of M. Basner and D. F. Dinges was funded by the National Space Biomedical Research Institute (NSBRI) through NASA NCC 9-58 and by the Institute for Experimental Psychiatry Research Foundation. S.B. received a financial support from the BELSPO/PRODEX/ESA contract (42-000-90-380).”
Wang JH, Singh R, Benoit M, Keyhan M, Sylvester M, Hsieh M, Thathireddy A, Hsieh YJ, Matin AC.
(PI: D. Bajaj, NSBRI Postdoctoral Fellowship Program)
Journal Impact Factor: 3.823
Funding: “Funding sources: The National Institutes of Health (RR010601; AR007581; AR047838; AR062002; AR063351), the National Space Biomedical Research Institute (NASA contract NCC 9-58).”
Lau AG, Sun J, Hannah WB, Livingston EW, Heymann D, Bateman TA, Monahan PE.
Joint bleeding in factor VIII deficient mice causes an acute loss of trabecular bone and calcification of joint soft tissues which is prevented with aggressive factor replacement. Haemophilia. 2014 Apr 8. [Epub ahead of print]
Funding: “Baxter Health Care Corporation: Provided Investigator – Initiated Study support to Paul E. Monahan and Ted A. Bateman. NIH: P01 HL112761 – Paul E. Monahan. NIH: 5R01AR059221-02 -Ted A. Bateman. National Space Biomedical Research Institute: PF03003 through NASA NCC 9-58 – Anthony G Lau. Center for the Advancement of Science in Space (CASIS) – Ted A. Bateman.”
Lloyd SA, Loiselle AE, Zhang Y, Donahue HJ.
Evidence for the role of connexin 43-mediated intercellular communication in the process of intracortical bone resorption via osteocytic osteolysis.
(PI: J.A. Cartriene for the ePST software used in the study)
Journal Impact Factor: 3.099
Funding: From the Headnote: “We appreciate the National Space Biomedical Research Institute for supporting the development of the ePST™ program through NASA NCC 9-58.” From the Disclosure Statement: “This research was funded by a Dartmouth Center for Clinical and Translational Research SYNERGY Pilot Project Grant awarded to Mark Hegel.”
Pellegrino R, Kavakli IH, Goel N, Cardinale CJ, Dinges DF, Kuna ST, Maislin G, Van Dongen HP, Tufik S, Hogenesch JB, Hakonarson H, Pack AI.
A Novel BHLHE41 variant is associated with short sleep and resistance to sleep deprivation in humans.
Funding: “This work was supported in part by NIH grant P01 HL094307 and Institutional Development Fund from the Center for Applied Genomics at The Children’s Hospital of Philadelphia. Data analyzed from experiments on chronic partial sleep deprivation were supported by the National Space Biomedical Research Institute through NASA NCC 9-58, NIH NR004281, CTRC UL1RR024134 and the Department of the Navy, Office of Naval Research Award No. N00014-11-1-0361.”
Dhoble AS, Pullammanappallil PC.
Design and operation of an anaerobic digester for waste management and fuel generation during long term lunar mission.
Note: From the abstract: “The general Content of this Resolution was discussed and agreed at the 19th International Academy of Astronautics Humans in Space Symposium in Cologne, Germany, July 7 to 12, 2013 and finally endorsed by the 392 participants of the Symposium from 26 countries. This resolution thus reflects the opinion of a substantial percentage of the global Space Medicine and Physiology Community.”
Ochiai M, Niu A, Steffens H, Balogh W, Haubold H, Othman M, Doi T.
United Nations Human Space Technology Initiative (HSTI).
Note: From the abstract: “The Human Space Technology…aims to involve more countries in activities related to human spaceflight and space exploration and to increase the benefits from the outcome of such activities through international cooperation, to make space exploration a truly international effort.”
Note: From the abstract: “Cosmic Study Group SG3.19/1.10 was established in February 2013 under the aegis of the International Academy of Astronautics to consider and compare the dose limits adopted by various space agencies for astronauts in Low Earth Orbit…The present paper presents preliminary results of the study reported at a Symposium held in Turin by the Academy in July2013.”
Fu Q, Levine BD.
Pathophysiology of neurally mediated syncope: Role of cardiac output and total peripheral resistance.
Auton Neurosci. 2014 Jul 16. pii: S1566-0702(14)00098-8. [Epub ahead of print] Review.
Note: From the abstract: “The great versatility that characterizes it, makes U-BRAIN applicable in many of the fields in which there are data to be analyzed.” This article may be obtained online without charge.