NASA Spaceline Current Awareness List Current Awareness List #606 11 July 2014


This issue contains some articles from earlier in 2014. We will continue to fill in some of the publications from the early part of the year as time permits. Please note that the next issue of SPACELINE Current Awareness (List #607) will be sent on Monday, July 21.

 
Papers deriving from NASA support:
 
1
Smith SM, Zwart SR, Heer M, Hudson EK, Shackelford L, Morgan JL.
Men and women in space: Bone loss and kidney stone risk after long-duration spaceflight.
J Bone Miner Res. 2014 Jul;29(7):1639-45.
http://www.ncbi.nlm.nih.gov/pubmed/24470067
(PI: S.M. Smith)
Note: ISS results.
Journal Impact Factor: 6.128
Funding: “This project was funded by the NASA Human Research Program and by a grant from the German Federal Ministry for Economics and Technology/DLR Forschung unter Weltraumbedingungen (50WB0931) to MH.”
 
2
Koppelmans V, Erdeniz B, De Dios YE, Wood SJ, Reuter-Lorenz PA, Kofman I, Bloomberg JJ, Mulavara AP, Seidler RD.
Study protocol to examine the effects of spaceflight and a spaceflight analog on neurocognitive performance: Extent, longevity, and neural bases.
BMC Neurol. 2013 Dec 18;13:205.
http://www.ncbi.nlm.nih.gov/pubmed/24350728
(PI: R.D. Seidler)
Note: Future ISS. This article may be obtained online without charge.
Journal Impact Factor: 2.560
Funding: “This work is funded by NASA NNX11AR02G and through the NASA Cooperative Agreement NCC 9–58 with the National Space Biomedical Research Institute (awarded to RDS).”
 
3
Law J, Van Baalen M, Foy M, Mason SS, Mendez C, Wear ML, Meyers VE, Alexander D.
Relationship between carbon dioxide levels and reported headaches on the International Space Station.
J Occup Environ Med. 2014 May;56(5):477-83.
http://www.ncbi.nlm.nih.gov/pubmed/24806559
NOTE: ISS results.
Journal Impact Factor: 1.845
 
4
Beach JM, Mihaljevic T, Rajeswaran J, Marwick T, Edwards ST, Nowicki ER, Thomas J, Svensson LG, Griffin B, Gillinov AM, Blackstone EH.
Ventricular hypertrophy and left atrial dilatation persist and are associated with reduced survival after valve replacement for aortic stenosis.
J Thorac Cardiovasc Surg. 2014 Jan;147(1):362-9.e8. Epub 2013 Jan 11.
http://www.ncbi.nlm.nih.gov/pubmed/23312984
(PI: J. Thomas)
Note: This article may be obtained online without charge at http://www.jtcvsonline.org/article/S0022-5223%2812%2901541-3/fulltext
Journal Impact Factor: 3.526
Funding: “This work was supported by awards from the American Heart Association (to J.M.B.). It was also supported in part by the Donna and Ken Lewis Chair in Cardiothoracic Surgery (to T.M.); the Charles and Lorraine Moore Endowed Chair in Cardiovascular Imaging (to J.T.); the National Space Biomedical Research Institute through NASA NCC 9-58 (to J.T.); the Judith Dion Pyle Endowed Chair in Heart Valve Research (to A.M.G.); the John and Rosemary Brown Endowed Chair in Cardiovascular Medicine (to B.G.); and the Kenneth Gee and Paula Shaw, PhD, Chair in Heart Research (to E.H.B.).”
 
5
Faghih RT, Dahleh MA, Adler GK, Klerman EB, Brown EN.
Deconvolution of serum cortisol levels by using compressed sensing.
PLoS One. 2014 Jan 28;9(1):e85204.
http://www.ncbi.nlm.nih.gov/pubmed/24489656
(PI: E.B. Klerman)
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.370
Funding: “RTF’s work was supported in part by the NSF Graduate Fellowship. For this work ENB is supported in part by NIH DP1 OD003646 and NSF 0836720. MAD is supported in part by EFRI-0735956 while EBK is supported in part by NIH P01-AG09975, K24-HL105664, RC2-HL101340, R01-HL-11408, and HFP01603 and HFP02802 from the National Space Biomedical Research Institute through NASA NCC 9-58. Finally, GKA is supported in part by NIH K24 HL103845. Clinical studies were performed on the Brigham and Women’s Hospital General Clinical Research Center. Grants supporting the original data collection include NIH R01AR43130 (GKA), M01RR20635 (BWH GCRC), K01AG00661 (EBK), R01GM 53559 (ENB), and NASA NCC9-58 with the NSBRI.”
 
6
Lillehoj PB, Kaplan CW, He J, Shi W, Ho CM.
Rapid, electrical impedance detection of bacterial pathogens using immobilized antimicrobial peptides.
J Lab Autom. 2014 Feb;19(1):42-9. Epub 2013 Jul 12.
http://www.ncbi.nlm.nih.gov/pubmed/23850865
(PI: Y-C. Tai)
Journal Impact Factor: 1.457
Funding: “This work was funded by the following agencies: NASA National Space Biomedical Research Institute (grant NCC 9-58-317) and UCLA T32 Dentist-Scientist & Oral Health Scientist Training Program (grant DE 007296).”
 
7
Hall ET, Sá RC, Holverda S, Arai TJ, Dubowitz DJ, Theilmann RJ, Prisk GK, Hopkins SR.
The effect of supine exercise on the distribution of regional pulmonary blood flow measured using proton MRI.
J Appl Physiol (1985). 2014 Feb 15;116(4):451-61. Epub 2013 Dec 19.
http://www.ncbi.nlm.nih.gov/pubmed/24356515
(PI: R.C. Sá, NSBRI Postdoctoral Fellowship Program)
Journal Impact Factor: 3.484
Funding: “This study was supported by National Heart, Lung, and Blood Institute (NHLBI) Grant HL-080203 (Principal Investigator: G. K. Prisk). R. C. Sá’s work was supported by the National Space Biomedical Research Institute through NASA NCC 9–58. E. T. Hall was supported by NHLBI Grant 2T35-HL-007491.”
 
8
Causey L, Lewandowski BE.
A mathematical model of oxygen transport in skeletal muscle during hindlimb unloading.
Cleveland: NASA Glenn Research Center. 2014 March; 24p. NASA/TM-2014-216631.
http://ntrs.nasa.gov/search.jsp?R=20140006741&hterms=20140006741
Note: Hindlimb unloading study. This report may be obtained online without charge.
 
9
Hu M, Qin YX.
Dynamic fluid flow stimulation on cortical bone and alterations of the gene expressions of osteogenic growth factors and transcription factors in a rat functional disuse model.
Arch Biochem Biophys. 2014 Mar 1;545:154-61. Epub 2014 Jan 30.
http://www.ncbi.nlm.nih.gov/pubmed/24486201
(PI: Y.X. Qin)
Note: Hindlimb unloading study.
Journal Impact Factor: 3.370
Funding: “This research is kindly supported by the National Institute of Health (R01 AR52379 and AR61821), the US Army Medical Research and Materiel Command, and the National Space
Biomedical Research Institute through NASA Cooperative Agreement NCC 9-58.”
 
10
Xu K, Ta D, He R, Qin YX, Wang W.
Axial transmission method for long bone fracture evaluation by ultrasonic guided waves: Simulation, phantom and in vitro experiments.
Ultrasound Med Biol. 2014 Apr;40(4):817-27. Epub 2014 Jan 13.
http://www.ncbi.nlm.nih.gov/pubmed/24433749
(PI: Y.X. Qin)
Journal Impact Factor: 2.455
Funding: “This work was supported by the National Natural Science Foundation of China (NSFC, Grants 11174060, 11304043 and 11327405); the Ph.D. Programs Foundation, Ministry of  Education of China (Grant 20110071130004); the Science and Technology Support Program of Shanghai (Grant 13441901900); the New Century Excellent Talents Support Program, Ministry of Education of China (Grant NCET-10-0349); and the China Postdoctoral Science Foundation (Grant 2012 M520826). The work was also partially supported by the National Space Biomedical Research Institute through NASA Cooperative Agreement NCC 9-58 and by a New York State Foundation for Science, Technology and Innovation grant to Stony Brook University.”
 
11
Lin L, Oon HY, Lin W, Qin YX.
Principal trabecular structural orientation predicted by quantitative ultrasound is strongly correlated with µFEA determined anisotropic apparent stiffness.
Biomech Model Mechanobiol. 2014 Jan 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/24419558
(PI: Y.X. Qin)
Journal Impact Factor: 3.331
Funding: “This work is kindly supported by the National Space Biomedical Research Institute through NASA Cooperative Agreement NCC 9-58, NIH (AR52379 & AR61821), and NYSTAR.”
 
12
Watson AB.
A formula for human retinal ganglion cell receptive field density as a function of visual field location.
J Vis. 2014 Jun 30;14(7). pii: 15.
http://www.ncbi.nlm.nih.gov/pubmed/24982468
Note: This article may be obtained online without charge.
Journal Impact Factor: 2.479
Funding: “This work supported by the NASA Space Human Factors Research Project WBS 466199.”
 
13
Zhou Y, Ni H, Balint K, Sanzari JK, Dentchev T, Diffenderfer ES, Wilson JM, Cengel KA, Weissman D.
Ionizing radiation selectively reduces skin regulatory T cells and alters immune function.
PLoS One. 2014 Jun 24;9(6):e100800.
http://www.ncbi.nlm.nih.gov/pubmed/24959865
(PI: A.R. Kennedy)
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.730
Funding: “This work was supported by a grant from the National Space Biomedical Research Institute through National Aeronautics and Space Administration NCC 9-58.”
 
14
Li M, Holmes V, Zhou Y, Ni H, Sanzari JK, Kennedy AR, Weissman D.
Hindlimb suspension and SPE-like radiation impairs clearance of bacterial infections.
PLoS One. 2014 Jan 15;9(1):e85665.
http://www.ncbi.nlm.nih.gov/pubmed/24454913
(PI: A.R. Kennedy)
Note: Hindlimb unloading study. This article may be obtained online without charge.
Journal Impact Factor: 3.730
Funding: “This work was supported by a grant from the National Space Biomedical Research Institute (NSBRI) through NASA NCC 9-58.”
 
15
Ftouni S, Rahman SA, Crowley KE, Anderson C, Rajaratnam SM, Lockley SW.
Temporal dynamics of ocular indicators of sleepiness across sleep restriction.
J Biol Rhythms. 2013 Dec;28(6):412-24.
http://www.ncbi.nlm.nih.gov/pubmed/24336419
(PI: S.W. Lockley)
Journal Impact Factor: 3.229
Funding: “This work was supported by the National Space Biomedical Research Institute (HPF01301). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Center for Research Resources or the National Institutes of Health. The project described was supported by Brigham and Women’s Hospital General Clinical Research Center grant M01 RR02635 and by Clinical Translational Science Award UL1RR025758 to Harvard University and Brigham and Women’s Hospital from the National Center for Research Resources. Optalert equipment was supported by grant FA9550-05-1-0197 (Czeisler) and grant FA9550-07-1-0242 (Czeisler) from the Air Force Office of Scientific Research (AFOSR): Defense University Research Instrumentation Program (DURIP). S.A.R. and S.W.L. were supported in part by the National Space Biomedical Research Institute through NASA NCC 9-58. S.F. was supported by student funding provided by the Australian Victoria Government Fellowship. K.E.C. was supported in-part by an unrestricted fellowship to SWL from Optalert Pty Ltd.”
 
16
Harper JD, Dunmire B, Wang YN, Simon JC, Liggitt D, Paun M, Cunitz BW, Starr F, Bailey MR, Penniston KL, Lee FC, Hsi RS, Sorensen MD.
Preclinical safety and effectiveness studies of ultrasonic propulsion of kidney stones.
http://www.ncbi.nlm.nih.gov/pubmed/24975708
(PI: M.R. Bailey)
Journal Impact Factor: 2.424
Funding: “This work supported by National Institutes of Health DK43881, DK092197, the National Space and Biomedical Research Institute through NASA NCC 9-58, the Wallace H. Coulter Foundation, and the Institute of Translational Health Science. This material is the result of work supported by resources from the VA Puget Sound Health Care System, Seattle, Washington.”
 
17
Watkins JM, Hechler PJ, Muday GK.
Ethylene-induced flavonol accumulation in guard cells suppresses reactive oxygen species and moderates stomatal aperture.
Plant Physiol. 2014 Apr;164(4):1707-17. Epub 2014 Mar 4.
http://www.ncbi.nlm.nih.gov/pubmed/24596331
(PI: G.K. Muday)
Note: This article may be obtained online without charge.
Journal Impact Factor: 6.555
Funding: “This work was supported by the U.S. Department of Agriculture National Institute of Food and Agriculture program (grant no. 2009–65116–20436 to G.K.M.) and the National Aeronautics and Space Administration (grant no. NNX09AK82G to G.K.M.). Grants from the National Science Foundation Major Research Instrumentation Program supported the purchase of the stereomicroscope and laser scanning confocal microscopes used in these experiments (grant nos. NSF–DBI 0500702, MRI–0722926, and MRI–1039755) and the purchase of an Orbitrap Mass spectrometer (NSF award no. 947028).”
 
_________________________________________________________________________
 
Other papers of interest:
 
1
Verhaar AP, Hoekstra E, Tjon AS, Utomo WK, Deuring JJ, Bakker ER, Muncan V, Peppelenbosch MP.
Dichotomal effect of space flight-associated microgravity on stress-activated protein kinases in innate immunity.
Sci Rep. 2014 Jun 27;4:5468.
http://www.ncbi.nlm.nih.gov/pubmed/24968806
Note: Soyuz and sounding rocket results. This article may be obtained online without charge.
 
2
Horslen BC, Dakin CJ, Inglis JT, Blouin JS, Carpenter MG.
Modulation of human vestibular reflexes with increased postural threat.
J Physiol. 2014 Jun 27. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/24973412
 
3
Lackner JR.
Motion sickness: More than nausea and vomiting.
Exp Brain Res. 2014 Jun 25. [Epub ahead of print] Review.
http://www.ncbi.nlm.nih.gov/pubmed/24961738
Note: This article may be obtained online without charge.
 
4
Keshavarz B, Hettinger LJ, Kennedy RS, Campos JL.
Demonstrating the potential for dynamic auditory stimulation to contribute to motion sickness. PLoS One. 2014 Jul 1;9(7):e101016.
http://www.ncbi.nlm.nih.gov/pubmed/24983752
Note: This article may be obtained online without charge.
 
5
Buzzacott P, Mazur A, Wang Q, Lambrechts K, Theron M, Mansourati J, Guerrero F.
A new measure of decompression sickness in the rat.
Biomed Res Int. 2014;2014:123581. Epub 2014 May 25.
http://www.ncbi.nlm.nih.gov/pubmed/24963469
Note: This article may be obtained online without charge.
 
6
Grimm D, Pietsch J, Wehland M, Richter P, Strauch SM, Lebert M, Magnusson NE, Wise P, Bauer J.
The impact of microgravity-based proteomics research.
Expert Rev Proteomics. 2014 Jun 24:1-12. [Epub ahead of print] Review.
http://www.ncbi.nlm.nih.gov/pubmed/24957700
 
7
Wei L, Liu C, Kang L, Liu Y, Shi S, Wu Q, Li Y.
Experimental study on effect of simulated microgravity on structural chromosome instability of human peripheral blood lymphocytes.
PLoS One. 2014 Jun 25;9(6):e100595.
http://www.ncbi.nlm.nih.gov/pubmed/24963972.
Note: Microgravity simulated by rotary cell culture system. This article may be obtained online without charge.
 
8
Brooks NE, Myburgh KH.
Skeletal muscle wasting with disuse atrophy is multi-dimensional: The response and interaction of myonuclei, satellite cells and signaling pathways.
Front Physiol. 2014 Mar 17;5:99. Review.
http://www.ncbi.nlm.nih.gov/pubmed/24672488
Note: This article may be obtained online without charge.
 
9
Khajuria DK, Disha C, Razdan R, Mahapatra DR, Vasireddi R.
Prophylactic effects of propranolol versus the standard therapy on a new model of disuse osteoporosis in rats.
Sci Pharm. 2013 Dec 9;82(2):357-74.
http://www.ncbi.nlm.nih.gov/pubmed/24959400
Note: Hindlimb unloading study. This article may be obtained online without charge.
 
10
Chen YJ, Chang MC, Jane Yao CC, Lai HH, Chang JZ, Jeng JH.
Mechanoregulation of osteoblast-like MG-63 cell activities by cyclic stretching.
J Formos Med Assoc. 2014 Jul;113(7):447-53. Epub 2012 Dec 25.
http://www.ncbi.nlm.nih.gov/pubmed/24961187
Note: This article may be obtained online without charge.
 
11
Moore SR, Saidel GM, Knothe U, Knothe Tate ML.
Mechanistic, mathematical model to predict the dynamics of tissue genesis in bone defects via mechanical feedback and mediation of biochemical factors.
PLoS Comput Biol. 2014 Jun 26;10(6):e1003604.
http://www.ncbi.nlm.nih.gov/pubmed/24967742
Note: This article may be obtained online without charge.
 
12
Yang C, Chen J, Wu F, Li J, Liang P, Zhang H, Wang H, Li Y, Wan Y, Qin L, Liang KS, Dai Z, Li Y.
Effects of 60-day head-down bed rest on osteocalcin, glycolipid metabolism and their association with or without resistance training.
Clin Endocrinol (Oxf). 2014 Jun 26. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/24975467
Note: Bed rest study.
 
13
Tillakaratne NJ, Duru P, Fujino H, Zhong H, Xiao MS, Edgerton VR, Roy RR.
Identification of interneurons activated at different inclines during treadmill locomotion in adult rats.
J Neurosci Res. 2014 Jun 27. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/24975393
 
14
Schneider S, Cheung JJ, Frick H, Krehan S, Micke F, Sauer M, Dalecki M, Dern S.
When neuroscience gets wet and hardcore: Neurocognitive markers obtained during whole body water immersion.
Exp Brain Res. 2014 Jul 1. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/24980790
Note: Water immersion is used to simulate EVA conditions.
 
15
Hirata H, Tatsumi H, Hayakawa K, Sokabe M.
Non-channel mechanosensors working at focal adhesion-stress fiber complex.
Pflugers Arch. 2014 Jun 26. [Epub ahead of print] Review.
http://www.ncbi.nlm.nih.gov/pubmed/24965068
 
16
Dabagh M, Jalali P, Butler PJ, Tarbell JM.
Shear-induced force transmission in a multicomponent, multicell model of the endothelium.
J R Soc Interface. 2014 Sep 6;11(98). pii: 20140431.
http://www.ncbi.nlm.nih.gov/pubmed/24966239
 
17
Beurg M, Kim KX, Fettiplace R.
Conductance and block of hair-cell mechanotransducer channels in transmembrane channel-like protein mutants.
J Gen Physiol. 2014 Jul;144(1):55-69.
http://www.ncbi.nlm.nih.gov/pubmed/24981230
 
18
Poole K, Moroni M, Lewin GR.
Sensory mechanotransduction at membrane-matrix interfaces.
Pflugers Arch. 2014 Jul 2. [Epub ahead of print] Review.
http://www.ncbi.nlm.nih.gov/pubmed/24981693
Note: This article may be obtained online without charge.
 
19
Plant TD.
TRPs in mechanosensing and volume regulation.
Handb Exp Pharmacol. 2014;223:743-66. Review.
http://www.ncbi.nlm.nih.gov/pubmed/24961968
 
20
Nair PM, Chung IM.
Impact of copper oxide nanoparticles exposure on Arabidopsis thaliana growth, root system development, root lignificaion, and molecular level changes.
Environ Sci Pollut Res Int. 2014 Jun 26. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/24965006
Note: From the abstract: “Exposure to CuONPs has resulted in retardation of primary root growth, enhanced lateral root formation, and also resulted in loss of root gravitropism.”
 
21
Hung CY, Aspesi P Jr, Hunter MR, Lomax AW, Perera IY.
Phosphoinositide-signaling is one component of a robust plant defense response.
Front Plant Sci. 2014 Jun 11;5:267.
http://www.ncbi.nlm.nih.gov/pubmed/24966862
Note: This article may be obtained online without charge.
 
22
Yu YT, Li GK, Yang ZL, Hu JG, Zheng JR, Qi XT.
Identification of a major quantitative trait locus for ear size induced by space flight in sweet corn.
Genet Mol Res. 2014 Apr 17;13(2):3069-78.
http://www.ncbi.nlm.nih.gov/pubmed/24782164
Note: Seeds were flown on a recoverable satellite. This article may be obtained online without charge.
 

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